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Christian Betzel

Christian Betzel

D-Index & Metrics

Chemistry

D-Index
63
Citations
14272
World Ranking
8418
National Ranking
609

Overview

Christian Betzel is affiliated with Universität Hamburg in Germany, where their research spans several areas within biochemistry, genetics, and molecular biology. Their work covers a wide array of subfields including molecular biology, materials chemistry, infectious diseases, biotechnology, and biomedical engineering.

The scientist's research interests are reflected in the main topics of their publications, which focus on enzyme structure and function, SARS-CoV-2 and COVID-19 research, RNA research and splicing, antimicrobial peptides and activities, interferon and immune responses, advanced X-ray imaging techniques, and broader biochemical and molecular research.

Christian Betzel has contributed to multiple publication venues. The most frequent venues include:

  • Scientific Reports
  • Communications Biology
  • IUCrJ
  • Toxins
  • Soft Matter

Their recent papers demonstrate involvement in diverse cutting-edge topics. Notable publications include:

  • Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates (2022, The EMBO Journal)
  • Structural characterization and antibacterial activity of silver nanoparticles synthesized using a low-molecular-weight Royal Jelly extract (2022, Scientific Reports)
  • Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease (2022, Communications Biology)
  • The XBI BioLab for life science experiments at the European XFEL (2020, Journal of Applied Crystallography)
  • Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive (2022, IUCrJ)

Christian Betzel collaborates regularly with a core group of coauthors. Frequent collaborators include:

  • Sven Falke
  • H. Brognaro
  • Robin Schubert
  • Markus Perbandt
  • Carsten Wrenger

This broad and interdisciplinary scope reflects a research profile deeply engaged in structural and functional biochemical studies, with applications relevant to infectious diseases and advanced imaging methods.

Best Publications

  • Molecular structure of the acyl-enzyme intermediate in β-lactam hydrolysis at 1.7 Å resolution

    Natalie C. J. Strynadka;Hiroyuki Adachi;Susan E. Jensen;Kathy Johns

  • Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser

    Lars Redecke;Lars Redecke;Karol Nass;Daniel P. DePonte;Thomas A. White

  • Topography of cyclodextrin inclusion complexes, part 20. Circular and flip-flop hydrogen bonding in .beta.-cyclodextrin undecahydrate: a neutron diffraction study

    Christian Betzel;Wolfram Saenger;Brian E. Hingerty;George M. Brown

  • Three-dimensional structure of system I of photosynthesis at 6 Å resolution

    Norbert Krauss;Winfried Hinrichs;Ingrid Witt;Ingrid Witt;Petra Fromme

  • Synthesis of stoichiometric nano crystalline hydroxyapatite by ethanol-based sol–gel technique at low temperature

    T.Anee Kuriakose;S.Narayana Kalkura;M. Palanichamy;D. Arivuoli

  • Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis.

    Tse Siang Kang;Dessislava Georgieva;Nikolay Genov;Mário T. Murakami

  • X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease.

    Sebastian Günther;Patrick Y. A. Reinke;Yaiza Fernández-García;Julia Lieske

  • Room-temperature macromolecular serial crystallography using synchrotron radiation.

    Francesco Stellato;Dominik Oberthür;Mengning Liang;Richard Bean

  • Serial crystallography on in vivo grown microcrystals using synchrotron radiation

    Cornelius Gati;Gleb Bourenkov;Marco Klinge;Dirk Rehders

  • Three-dimensional structure of proteinase K at 0.15-nm resolution

    Christian Betzel;Gour P. Pal;Wolfram Saenger

  • Crystal structure of the alkaline proteinase Savinase from Bacillus lentus at 1.4 A resolution.

    Christian Betzel;Silke Klupsch;Gerlind Papendorf;Sven Hastrup

  • In vivo protein crystallization opens new routes in structural biology

    Rudolf Koopmann;Karolina Cupelli;Lars Redecke;Karol Nass

  • Megahertz serial crystallography

    Max O. Wiedorn;Dominik Oberthür;Richard Bean;Robin Schubert;Robin Schubert

  • Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta-mediated neurotoxicity.

    Clemens Falker;Alexander Hartmann;Inga Guett;Frank Dohler

  • Structure of a serine protease proteinase K from Tritirachium album limber at 0.98 A resolution.

    Christian Betzel;S. Gourinath;Pravindra Kumar;Punit Kaur

  • Structure of catalase-A from Saccharomyces cerevisiae.

    Maria J. Maté;Marcel Zamocky;Leena M. Nykyri;Christian Herzog

  • Crystal structure of catalase HPII from Escherichia coli

    Jerónimo Bravo;Núria Verdaguer;José Tormo;Christian Betzel

  • Snake Venom Peptides: Tools of Biodiscovery.

    Aisha Munawar;Syed Abid Ali;Ahmed Akrem;Christian Betzel

  • The refined crystal structure of Pseudomonas putida lipoamide dehydrogenase complexed with NAD+ at 2.45 A resolution.

    Andrea Mattevi;Galya Obmolova;John R. Sokatch;Christian Betzel

  • X-ray structure of lipoamide dehydrogenase from Azotobacter vinelandii determined by a combination of molecular and isomorphous replacement techniques

    A.J. Schierbeek;M.B.A. Swarte;B.W. Dijkstra;G. Vriend

  • Flip-flop hydrogen bonding in a partially disordered system

    W. Saenger;W. Saenger;Ch. Betzel;B. Hingerty;G. M. Brown

Frequent Co-Authors

Henry N. Chapman
Henry N. Chapman Universität Hamburg
Rolf Hilgenfeld
Rolf Hilgenfeld University of Lübeck
Matthias Rarey
Matthias Rarey Universität Hamburg
Volker A. Erdmann
Volker A. Erdmann Freie Universität Berlin
Dušan Turk
Dušan Turk Jožef Stefan Institute
Keith S. Wilson
Keith S. Wilson University of York
Wolfgang Voelter
Wolfgang Voelter University of Tübingen
Wolfram Saenger
Wolfram Saenger Freie Universität Berlin
Martin von Bergen
Martin von Bergen Helmholtz Centre for Environmental Research
Dmitri I. Svergun
Dmitri I. Svergun European Bioinformatics Institute

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