World's Best Scientists 2026 revealed!
Tetsu Akiyama

Tetsu Akiyama

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
34012
World Ranking
3256
National Ranking
202

Overview

Tetsu Akiyama is affiliated with the University of Tokyo in Japan. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with considerable work also intersecting Medicine. Key subfields in their work include Molecular Biology, Infectious Diseases, Cancer Research, Immunology, and Dermatology.

Their research output encompasses a variety of main topics such as SARS-CoV-2 and COVID-19 research, COVID-19 clinical research studies, single-cell and spatial transcriptomics, inflammasome and immune disorders, contact dermatitis and allergies, phagocytosis and immune regulation, and the role of gut microbiota in health.

Frequent coauthors collaborating with Akiyama include:

  • Yasunari Kageyama
  • Tsutomu Nakamura
  • Koichi Aida
  • Tomoatsu Hayashi
  • Kimihiko Kawauchi

Akiyama has published papers in several scientific journals, among which the most recurrent venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Science
  • Scientific Reports
  • World Academy of Sciences Journal
  • Current Issues in Molecular Biology

Recent publications include:

  • Metalloproteinase-Dependent and TMPRSS2-Independent Cell Surface Entry Pathway of SARS-CoV-2 Requires the Furin Cleavage Site and the S2 Domain of Spike Protein, 2022, mBio
  • Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells, 2020, Oncogene
  • Lactobacillus plantarum induces innate cytokine responses that potentially provide a protective benefit against COVID-19: A single-arm, double-blind, prospective trial combined with an in vitro cytokine response assay, 2021, Experimental and Therapeutic Medicine
  • PHOSPHATE exporter XPR1/SLC53A1 is required for the tumorigenicity of epithelial ovarian cancer, 2022, Cancer Science
  • FXYD3 functionally demarcates an ancestral breast cancer stem cell subpopulation with features of drug-tolerant persisters, 2023, Journal of Clinical Investigation

Best Publications

  • Genistein, a specific inhibitor of tyrosine-specific protein kinases.

    T Akiyama;J Ishida;S Nakagawa;H Ogawara

  • Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor.

    Tadashi Yamamoto;Shuntaro Ikawa;Tetsu Akiyama;Tetsu Akiyama;Kentaro Semba

  • The product of the human c-erbB-2 gene: a 185-kilodalton glycoprotein with tyrosine kinase activity.

    Tetsu Akiyama;Chie Sudo;Hiroshi Ogawara;Kumao Toyoshima

  • The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells.

    Yusuke Hirabayashi;Yasuhiro Itoh;Hidenori Tabata;Kazunori Nakajima;Kazunori Nakajima

  • Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

    Tohru Kiyono;Atsuro Hiraiwa;Masatoshi Fujita;Yasuyuki Hayashi

  • Rapid Colorectal Adenoma Formation Initiated by Conditional Targeting of the Apc Gene

    Hiroyuki Shibata;Kaoru Toyama;Hisashi Shioya;Masaki Ito

  • DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway.

    Atsushi Niida;Takatoshi Hiroko;Mana Kasai;Yoichi Furukawa

  • Helicobacter pylori CagA interacts with E-cadherin and deregulates the β-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells

    N Murata-Kamiya;Y Kurashima;Y Teishikata;Y Yamahashi

  • Wnt/beta-catenin signaling.

    Tetsu Akiyama

  • Binding of APC to the Human Homolog of the Drosophila Discs Large Tumor Suppressor Protein

    Akihiko Matsumine;Akiko Ogai;Takao Senda;Nobuaki Okumura

  • Use and specificity of genistein as inhibitor of protein-tyrosine kinases.

    Tetsu Akiyama;Hiroshi Ogawara

  • Interaction with IQGAP1 Links APC to Rac1, Cdc42, and Actin Filaments during Cell Polarization and Migration

    Takashi Watanabe;Shujie Wang;Jun Noritake;Kazumasa Sato

  • The muscle protein Dok-7 is essential for neuromuscular synaptogenesis.

    Kumiko Okada;Akane Inoue;Momoko Okada;Yoji Murata

  • Asef, a link between the tumor suppressor APC and G-protein signaling.

    Yoshihiro Kawasaki;Takao Senda;Takao Ishidate;Ryo Koyama

  • In vitro effects on microtubule dynamics of purified Xenopus M phase-activated MAP kinase.

    Yukiko Gotoh;Eisuke Nishida;Satoshi Matsuda;Nobuyuki Shiina

  • PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-d-aspartate receptor subunit NR2A

    Tohru Tezuka;Hisashi Umemori;Tetsu Akiyama;Shigetada Nakanishi

  • Inhibition of Wnt signaling by ICAT, a novel β-catenin-interacting protein

    Ken-ichi Tago;Tsutomu Nakamura;Michiru Nishita;Junko Hyodo

  • Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level

    Tsutomu Nakamura;Fumihiko Hamada;Fumihiko Hamada;Takao Ishidate;Takao Ishidate;Ken-ichi Anai

  • Identification of a link between the tumour suppressor APC and the kinesin superfamily

    Takeshi Jimbo;Yoshihiro Kawasaki;Ryo Koyama;Rina Sato

  • Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: implications for the involvement of WT1 in leukemogenesis

    T Yamagami;H Sugiyama;K Inoue;H Ogawa

Frequent Co-Authors

Tadashi Yamamoto
Tadashi Yamamoto Okinawa Institute of Science and Technology
Kumao Toyoshima
Kumao Toyoshima Osaka University
Katsuhiko Shirahige
Katsuhiko Shirahige University of Tokyo
Hiroyuki Aburatani
Hiroyuki Aburatani University of Tokyo
Yasuyuki Morishita
Yasuyuki Morishita University of Tokyo
Tomoki Todo
Tomoki Todo University of Tokyo
Mikako Shirouzu
Mikako Shirouzu RIKEN Center for Biosystems Dynamics Research
Shigeaki Kato
Shigeaki Kato University of Tokyo

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Biology and Biochemistry in the USA opens doors to a wide variety of online degrees and professional pathways. Many students expand their expertise or shift careers by pursuing healthcare, nutrition, research, or education-focused qualifications online.

For those seeking a faster route to advanced clinical practice, the shortest online nurse practitioner program options can be an efficient way to enter or enhance a nursing career. Similarly, professionals interested in nutrition and wellness can benefit from the cheapest online nutrition degree programs to build relevant skills without incurring high tuition costs.

Registered nurses aiming to elevate their qualifications should explore online rn to bsn programs designed for working professionals, making the transition to a bachelor’s degree more accessible. Also, those interested in health administration may consider the online masters healthcare management options for leadership roles.

Best Scientists Citing Tetsu Akiyama

Trending Scientists

Recently Published Articles