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Yukiko Gotoh

Yukiko Gotoh

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Biology and Biochemistry
Japan
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
42431
World Ranking
2276
National Ranking
140

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Yukiko Gotoh is a researcher affiliated with the University of Tokyo in Japan, specializing in the field of Biochemistry, Genetics and Molecular Biology. Their work encompasses a wide range of subfields including Molecular Biology, Immunology, Genetics, Developmental Neuroscience, and Plant Science.

Their research addresses several key topics such as:

  • Epigenetics and DNA Methylation
  • RNA Research and Splicing
  • Neurogenesis and Neuroplasticity Mechanisms
  • Genetics and Neurodevelopmental Disorders
  • Genomics and Chromatin Dynamics
  • Interferon and Immune Responses
  • Pluripotent Stem Cells Research

Yukiko Gotoh has contributed to a number of scientific publications across various respected journals. Their recent papers include:

  • "Setd1a Insufficiency in Mice Attenuates Excitatory Synaptic Function and Recapitulates Schizophrenia-Related Behavioral Abnormalities" (2020, Cell Reports)
  • "Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module" (2021, Nature Communications)
  • "The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon" (2020, Nature Communications)
  • "Maintenance of Neural Stem-Progenitor Cells by the Lysosomal Biosynthesis Regulators TFEB and TFE3 in the Embryonic Mouse Telencephalon" (2021, Stem Cells)
  • "Role of the imprinted allele of the Cdkn1c gene in mouse neocortical development" (2020, Scientific Reports)

The venues in which Yukiko Gotoh frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Aging Cell
  • Scientific Reports
  • STAR Protocols

Collaboration is a component of their work, with frequent co-authors including:

  • Yusuke Kishi
  • Hiroki Sugishita
  • Daichi Kawaguchi
  • Mai Saeki
  • Yujin Harada

The breadth of Yukiko Gotoh's work spans molecular mechanisms governing neurodevelopment, epigenetic regulation, and immune responses, reflecting a multidisciplinary approach to understanding biological complexity.

Best Publications

  • Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

    Sandeep Robert Datta;Henryk Dudek;Xu Tao;Shane Masters

  • Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

    Shigeaki Kato;Hideki Endoh;Yoshikazu Masuhiro;Takuya Kitamoto

  • Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

    Hidenori Ichijo;Eisuke Nishida;Kenji Irie;Peter ten Dijke

  • The MAP kinase cascade is essential for diverse signal transduction pathways.

    Eisuke Nishida;Yukiko Gotoh

  • Akt Enhances Mdm2-mediated Ubiquitination and Degradation of p53 *

    Yoko Ogawara;Shohei Kishishita;Toshiyuki Obata;Yuko Isazawa

  • TAB1: An activator of the TAK1 MAPKKK in TGF-β signal transduction

    Hiroshi Shibuya;Kyoko Yamaguchi;Kyoko Shirakabe;Akane Tonegawa

  • The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells.

    Yusuke Hirabayashi;Yasuhiro Itoh;Hidenori Tabata;Kazunori Nakajima;Kazunori Nakajima

  • β-Amyloid Induces Neuronal Apoptosis Via a Mechanism that Involves the c-Jun N-Terminal Kinase Pathway and the Induction of Fas Ligand

    Yoshiyuki Morishima;Yukiko Gotoh;Janine Zieg;Tamera Barrett

  • JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins

    Fuminori Tsuruta;Jun Sunayama;Yasunori Mori;Seisuke Hattori

  • A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3.

    Tetsuo Moriguchi;Noriyo Kuroyanagi;Kyoko Yamaguchi;Yukiko Gotoh

  • Activation and Involvement of p38 Mitogen-activated Protein Kinase in Glutamate-induced Apoptosis in Rat Cerebellar Granule Cells *

    Hiroshi Kawasaki;Takaya Morooka;Shun Shimohama;Jun Kimura

  • Hes binding to STAT3 mediates crosstalk between Notch and JAK–STAT signalling

    Sachiko Kamakura;Koji Oishi;Takeshi Yoshimatsu;Masato Nakafuku

  • Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells : identity with the mitogen-activated MAP kinase of fibroblastic cells

    Yukiko Gotoh;Eisuke Nishida;Takashi Yamashita;Minako Hoshi

  • The Phosphatidylinositol 3-Kinase (PI3K)-Akt Pathway Suppresses Bax Translocation to Mitochondria

    Fuminori Tsuruta;Norihisa Masuyama;Yukiko Gotoh;Yukiko Gotoh

  • Reactive Oxygen Species- and Dimerization-induced Activation of Apoptosis Signal-regulating Kinase 1 in Tumor Necrosis Factor-α Signal Transduction

    Yukiko Gotoh;Jonathan A. Cooper

  • Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition.

    Yusuke Hirabayashi;Nao Suzki;Masafumi Tsuboi;Takaho A. Endo

  • A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C.

    K S Lee;K Irie;Y Gotoh;Y Watanabe

  • Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase

    Makoto Fukuda;Yukiko Gotoh;Eisuke Nishida

  • In vitro effects on microtubule dynamics of purified Xenopus M phase-activated MAP kinase.

    Yukiko Gotoh;Eisuke Nishida;Satoshi Matsuda;Nobuyuki Shiina

  • Caspase‐mediated activation and induction of apoptosis by the mammalian Ste20‐like kinase Mst1

    Jonathan D. Graves;Yukiko Gotoh;Yukiko Gotoh;Kevin E. Draves;Diane Ambrose

Frequent Co-Authors

Hidetaka Kosako
Hidetaka Kosako University of Tokushima
Kunihiro Matsumoto
Kunihiro Matsumoto Nagoya University
Haruhiko Koseki
Haruhiko Koseki RIKEN Center for Integrative Medical Sciences
Hikoichi Sakai
Hikoichi Sakai University of Tokyo
Kenji Irie
Kenji Irie University of Tsukuba
Yasushi Okada
Yasushi Okada University of Tokyo
Akihiro Iwamatsu
Akihiro Iwamatsu Osaka University
Kazunori Nakajima
Kazunori Nakajima Keio University
Kunihiro Ohta
Kunihiro Ohta University of Tokyo

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