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Yasushi Okada

Yasushi Okada

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
20375
World Ranking
12923
National Ranking
895

Overview

Yasushi Okada is affiliated with the University of Tokyo in Japan with a research focus spanning biochemistry, genetics, and molecular biology. Their scholarly contributions particularly emphasize molecular biology, cell biology, and biophysics, supported by extensive work in genetics and cellular and molecular neuroscience.

The main topics addressed in Yasushi Okada's work include:

  • RNA Research and Splicing
  • Advanced Fluorescence Microscopy Techniques
  • Microtubule and Mitosis Dynamics
  • RNA Modifications and Cancer
  • Mitochondrial Function and Pathology
  • Photoreceptor and Optogenetics Research
  • Congenital Heart Defects Research

Yasushi Okada's recent scientific papers encompass a range of subjects within cell and molecular biology, including:

  • "Phase separation organizes the site of autophagosome formation," 2020, Nature
  • "A highly photostable and bright green fluorescent protein," 2022, Nature Biotechnology
  • "Immotile cilia mechanically sense the direction of fluid flow for left-right determination," 2023, Science
  • "StayGold variants for molecular fusion and membrane-targeting applications," 2023, Nature Methods
  • "Condensed but liquid-like domain organization of active chromatin regions in living human cells," 2023, Science Advances

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Biophysical Journal, Scientific Reports, Nature Biotechnology, and Communications Biology. The most frequent venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • Scientific Reports
  • Nature Biotechnology
  • Communications Biology

Yasushi Okada collaborates regularly with several coauthors. Frequent collaborators include Sawako Enoki, Takanobu A. Katoh, Hiroshi Hamada, Masahiko Hirano, and Ryoko Ando.

Best Publications

  • Randomization of Left–Right Asymmetry due to Loss of Nodal Cilia Generating Leftward Flow of Extraembryonic Fluid in Mice Lacking KIF3B Motor Protein

    Shigenori Nonaka;Yosuke Tanaka;Yasushi Okada;Sen Takeda

  • A standardized kinesin nomenclature.

    Carolyn J. Lawrence;R. Kelly Dawe;Karen R. Christie;Don W. Cleveland

  • Analysis of the kinesin superfamily: insights into structure and function.

    Harukata Miki;Yasushi Okada;Nobutaka Hirokawa

  • The neuron-specific kinesin superfamily protein KIF1A is a uniqye monomeric motor for anterograde axonal transport of synaptic vesicle precursors

    Yasushi Okada;Hiroto Yamazaki;Yoko Sekine-Aizawa;Nobutaka Hirokawa

  • Targeted Disruption of Mouse Conventional Kinesin Heavy Chain kif5B, Results in Abnormal Perinuclear Clustering of Mitochondria

    Yosuke Tanaka;Yoshimitsu Kanai;Yasushi Okada;Shigenori Nonaka

  • KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria

    Masaomi Nangaku;Reiko Sato-Yoshitake;Yasushi Okada;Yasuko Noda

  • FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left–right determination

    Yosuke Tanaka;Yasushi Okada;Nobutaka Hirokawa

  • Nodal flow and the generation of left-right asymmetry.

    Nobutaka Hirokawa;Yosuke Tanaka;Yasushi Okada;Sen Takeda

  • A Processive Single-Headed Motor: Kinesin Superfamily Protein KIF1A

    Yasushi Okada;Nobutaka Hirokawa

  • Mechanism of Nodal Flow: A Conserved Symmetry Breaking Event in Left-Right Axis Determination

    Yasushi Okada;Sen Takeda;Yosuke Tanaka;Juan-Carlos Izpisúa Belmonte

  • Left-Right Asymmetry and Kinesin Superfamily Protein KIF3A: New Insights in Determination of Laterality and Mesoderm Induction by kif3A−/− Mice Analysis

    Sen Takeda;Yoshiaki Yonekawa;Yosuke Tanaka;Yasushi Okada

  • Abnormal Nodal Flow Precedes Situs Inversus in iv and inv mice

    Yasushi Okada;Shigenori Nonaka;Yosuke Tanaka;Yukio Saijoh

  • A spontaneously blinking fluorophore based on intramolecular spirocyclization for live-cell super-resolution imaging

    Shin Nosuke Uno;Mako Kamiya;Toshitada Yoshihara;Ko Sugawara

  • KINESIN AND DYNEIN SUPERFAMILY PROTEINS IN ORGANELLE TRANSPORT AND CELL DIVISION

    Nobutaka Hirokawa;Yasuko Noda;Yasushi Okada

  • Dynamic Organization of Chromatin Domains Revealed by Super-Resolution Live-Cell Imaging

    Tadasu Nozaki;Ryosuke Imai;Mai Tanbo;Mai Tanbo;Ryosuke Nagashima;Ryosuke Nagashima

  • Switch-based Mechanism of Kinesin Motors

    Masahide Kikkawa;Elena P. Sablin;Yasushi Okada;Hiroaki Yajima

  • Mechanism of the single-headed processivity: Diffusional anchoring between the K-loop of kinesin and the C terminus of tubulin

    Yasushi Okada;Nobutaka Hirokawa

  • KIF5C, a Novel Neuronal Kinesin Enriched in Motor Neurons

    Yoshimitsu Kanai;Yasushi Okada;Yosuke Tanaka;Akihiro Harada

  • Defect in Synaptic Vesicle Precursor Transport and Neuronal Cell Death in KIF1A Motor Protein–deficient Mice

    Yoshiaki Yonekawa;Akihiro Harada;Yasushi Okada;Takeshi Funakoshi

  • KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport.

    H Yamazaki;T Nakata;Y Okada;N Hirokawa

Frequent Co-Authors

Nobutaka Hirokawa
Nobutaka Hirokawa University of Tokyo
Takeharu Nagai
Takeharu Nagai Osaka University
Yukiko Gotoh
Yukiko Gotoh University of Tokyo
Hiroshi Hamada
Hiroshi Hamada RIKEN Center for Biosystems Dynamics Research
Masaomi Nangaku
Masaomi Nangaku University of Tokyo
Robert J. Fletterick
Robert J. Fletterick University of California, San Francisco
Masaru Tomita
Masaru Tomita Keio University
Mikako Shirouzu
Mikako Shirouzu RIKEN Center for Biosystems Dynamics Research
Tetsushi Sakuma
Tetsushi Sakuma Hiroshima University
Hiroyuki Fujita
Hiroyuki Fujita Tokyo City University

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