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Biology and Biochemistry

D-Index
52
Citations
12664
World Ranking
16530
National Ranking
6843

Research.com Recognitions

  • 2009 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Linda Wordeman is a researcher affiliated with the University of Washington in the United States. Their work primarily spans the broad field of Biochemistry, Genetics, and Molecular Biology, with significant contributions in Molecular Biology, Cell Biology, Genetics, Biophysics, and Organic Chemistry.

The research topics Linda Wordeman focuses on include:

  • Microtubule and mitosis dynamics
  • Histone Deacetylase Inhibitors Research
  • Glioma Diagnosis and Treatment
  • Cell Image Analysis Techniques
  • Cellular Mechanics and Interactions
  • Ubiquitin and proteasome pathways
  • Protein Degradation and Inhibitors

Recent publications authored or co-authored by Linda Wordeman include:

  • "Microtubule Targeting Agents in Disease: Classic Drugs, Novel Roles," 2021, published in Cancers
  • "A brain-penetrant microtubule-targeting agent that disrupts hallmarks of glioma tumorigenesis," 2020, Neuro-Oncology Advances
  • "Phosphorylation of NMDA receptors by cyclin B/CDK1 modulates calcium dynamics and mitosis," 2020, Communications Biology
  • "KIF2C/MCAK a prognostic biomarker and its oncogenic potential in malignant progression, and prognosis of cancer patients: a systematic review and meta-analysis as biomarker," 2024, Critical Reviews in Clinical Laboratory Sciences
  • "Non-enzymatic Activity of the α-Tubulin Acetyltransferase αTAT Limits Synaptic Bouton Growth in Neurons," 2020, Current Biology

Frequent co-authors collaborating with Linda Wordeman include:

  • Juan Jesus Vicente
  • Michael Wagenbach
  • Nephi Stella
  • John D. Scott
  • Paula Bucko

The researcher has published multiple articles in prominent scientific venues such as:

  • Neuro-Oncology
  • Current Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The FASEB Journal
  • Cell Biology International

Linda Wordeman was recognized as a Fellow of the John Simon Guggenheim Memorial Foundation in 2009.

Best Publications

  • A standardized kinesin nomenclature.

    Carolyn J. Lawrence;R. Kelly Dawe;Karen R. Christie;Don W. Cleveland

  • Preparation of modified tubulins

    Anthony Hyman;David Drechsel;Doug Kellogg;Steve Salser

  • Aurora B Regulates MCAK at the Mitotic Centromere

    Paul D Andrews;Yulia Ovechkina;Nick Morrice;Michael Wagenbach

  • Localization of cytoplasmic dynein to mitotic spindles and kinetochores

    E. R. Steuer;L. Wordeman;T. A. Schroer;Michael Sheetz

  • Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis.

    Linda Wordeman;Timothy J. Mitchison

  • The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends.

    Andrew W. Hunter;Michael Caplow;David L. Coy;William O. Hancock

  • Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends

    Leticia Peris;Manuel Thery;Julien Fauré;Yasmina Saoudi

  • The Kinesin-8 motor, Kif18A, Suppresses Kinetochore Movements to Control Mitotic Chromosome Alignment

    Jason Stumpff;George von Dassow;Michael Wagenbach;Charles Asbury

  • Motor-dependent microtubule disassembly driven by tubulin tyrosination

    Leticia Peris;Michael Wagenbach;Laurence Lafanechère;Laurence Lafanechère;Laurence Lafanechère;Jacques Brocard;Jacques Brocard;Jacques Brocard

  • Mitotic Centromere–associated Kinesin Is Important for Anaphase Chromosome Segregation

    Todd Maney;Andrew W. Hunter;Mike Wagenbach;Linda Wordeman

  • The Ndc80 Kinetochore Complex Forms Load-Bearing Attachments to Dynamic Microtubule Tips via Biased Diffusion

    Andrew F. Powers;Andrew D. Franck;Daniel R. Gestaut;Jeremy Cooper

  • The Kinesin-13 Proteins Kif2a, Kif2b, and Kif2c/MCAK Have Distinct Roles during Mitosis in Human Cells

    Amity L. Manning;Neil J. Ganem;Samuel F. Bakhoum;Michael Wagenbach

  • Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B.

    Jerry F. Tien;Neil T. Umbreit;Daniel R. Gestaut;Andrew D. Franck

  • Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells

    Norman Ertych;Ailine Stolz;Albrecht Stenzinger;Wilko Weichert

  • Molecular dissection of the microtubule depolymerizing activity of mitotic centromere-associated kinesin.

    Todd Maney;Michael Wagenbach;Linda Wordeman

  • Kif18A and Chromokinesins Confine Centromere Movements via Microtubule Growth Suppression and Spatial Control of Kinetochore Tension

    Jason Stumpff;Michael Wagenbach;Andrew Franck;Charles L. Asbury

  • Human centromeres and neocentromeres show identical distribution patterns of >20 functionally important kinetochore-associated proteins.

    Richard Saffery;Danielle V. Irvine;Belinda Griffiths;Paul Kalitsis

  • How kinesin motor proteins drive mitotic spindle function: Lessons from molecular assays.

    Linda Wordeman

  • Phosphoregulation and depolymerization-driven movement of the Dam1 complex do not require ring formation.

    Daniel R. Gestaut;Beth Graczyk;Jeremy Cooper;Per O. Widlund

  • Evidence for kinesin-related proteins in the mitotic apparatus using peptide antibodies

    Kenneth E. Sawin;Timothy J. Mitchison;Linda G. Wordeman

Frequent Co-Authors

John D. Scott
John D. Scott University of Washington
Nephi Stella
Nephi Stella University of Washington
Trisha N. Davis
Trisha N. Davis University of Washington
Timothy J. Mitchison
Timothy J. Mitchison Harvard University
Ernest Hamel
Ernest Hamel National Institutes of Health
Annie Andrieux
Annie Andrieux Grenoble Alpes University
Didier Job
Didier Job Grenoble Alpes University
Christopher J. Staiger
Christopher J. Staiger Purdue University West Lafayette
Eric C. Holland
Eric C. Holland Fred Hutchinson Cancer Research Center
Kent L. McDonald
Kent L. McDonald University of California, Berkeley

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