World's Best Scientists 2026 revealed!
Jonathon Howard

Jonathon Howard

D-Index & Metrics

Biology and Biochemistry

D-Index
96
Citations
36068
World Ranking
1806
National Ranking
997

Research.com Recognitions

  • 1996 - Fellow of John Simon Guggenheim Memorial Foundation
  • 1990 - Fellow of Alfred P. Sloan Foundation

Overview

Jonathon Howard is affiliated with Yale University in the United States and has made contributions primarily in the field of Biochemistry, Genetics, and Molecular Biology, with a particular emphasis on Cell Biology and Molecular Biology. Their research spans several interconnected subfields including Cellular and Molecular Neuroscience, Condensed Matter Physics, and Biophysics.

The main topics of Jonathon Howard's work encompass a range of cellular and molecular processes. These include:

  • Microtubule and mitosis dynamics
  • Cellular Mechanics and Interactions
  • Neurobiology and Insect Physiology Research
  • Micro and Nano Robotics
  • Cellular transport and secretion
  • Advanced Fluorescence Microscopy Techniques
  • Photoreceptor and optogenetics research

Their recent publications demonstrate a focus on cellular structures and mechanisms related to microtubules, cilia, and motor proteins, often examined with biophysical and biochemical approaches. Notable papers include:

  • "Physical bioenergetics: Energy fluxes, budgets, and constraints in cells" (2021), published in Proceedings of the National Academy of Sciences
  • "Cilia function as calcium-mediated mechanosensors that instruct left-right asymmetry" (2023), published in Science
  • "Cutting, Amplifying, and Aligning Microtubules with Severing Enzymes" (2020), published in Trends in Cell Biology
  • "Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism" (2021), published in Nature Structural & Molecular Biology
  • "Radial-velocity discovery of a second planet in the TOI-1338/BEBOP-1 circumbinary system" (2023), published in Nature Astronomy

Jonathon Howard has frequently collaborated with several coauthors, illustrating ongoing research partnerships in their scientific endeavors. Frequent coauthors include:

  • Yin-Wei Kuo
  • Sabyasachi Sutradhar
  • Yazgan Tuna
  • Maijia Liao
  • Sonal Shree

Their research has been published in a variety of venues, reflecting the interdisciplinary nature of their work. Some of the most common publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • arXiv (Cornell University)
  • Brain stimulation

Recognition of their scientific contributions includes awards such as Fellowships from prestigious organizations:

  • Fellow of John Simon Guggenheim Memorial Foundation, 1996
  • Fellow of Alfred P. Sloan Foundation, 1990

Best Publications

  • Mechanics of Motor Proteins and the Cytoskeleton

    J Howard;RL Clark

  • Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape.

    Frederick Gittes;Brian Mickey;Jilda Nettleton;Jonathon Howard

  • Correction: Corrigendum: A doublecortin containing microtubule-associated protein is implicated in mechanotransduction in Drosophila sensory cilia

    S. Bechstedt;J. T. Albert;D. P. Kreil;T. Müller-Reichert

  • Movement of microtubules by single kinesin molecules

    J. Howard;A. J. Hudspeth;R. D. Vale

  • A standardized kinesin nomenclature.

    Carolyn J. Lawrence;R. Kelly Dawe;Karen R. Christie;Don W. Cleveland

  • Compliance of the hair bundle associated with gating of mechanoelectrical transduction channels in the Bullfrog's saccular hair cell

    J. Howard;A.J. Hudspeth

  • A Self-Organized Vortex Array of Hydrodynamically Entrained Sperm Cells

    Ingmar H. Riedel;Karsten Kruse;Jonathon Howard

  • XMAP215 Is a Processive Microtubule Polymerase

    Gary J. Brouhard;Jeffrey H. Stear;Tim L. Noetzel;Jawdat Al-Bassam

  • The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends

    Jonne Helenius;Gary Brouhard;Yannis Kalaidzidis;Stefan Diez

  • A Measurement of the Cosmic Microwave Background B-Mode Polarization Power Spectrum at Sub-Degree Scales with POLARBEAR

    P.A.R. Ade;Y. Akiba;A.E. Anthony

  • Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner

    Vladimir Varga;Jonne Helenius;Kozo Tanaka;Anthony A. Hyman

  • Kinesin takes one 8-nm step for each ATP that it hydrolyzes.

    David L. Coy;Michael Wagenbach;Jonathon Howard

  • Mechanical relaxation of the hair bundle mediates adaptation in mechanoelectrical transduction by the bullfrog's saccular hair cell

    J Howard;A J Hudspeth

  • The force exerted by a single kinesin molecule against a viscous load

    A.J. Hunt;F. Gittes;J. Howard

  • The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends.

    Andrew W. Hunter;Michael Caplow;David L. Coy;William O. Hancock

  • Kinesin follows the microtubule's protofilament axis.

    Sanghamitra Ray;Edgar Meyhöfer;Ronald A. Milligan;Jonathon Howard

  • Light-Controlled Molecular Shuttles Made from Motor Proteins Carrying Cargo on Engineered Surfaces

    Henry Hess;John Clemmens;Dong Qin;Jonathon Howard

  • The distribution of active force generators controls mitotic spindle position.

    Stephan W. Grill;Jonathon Howard;Erik Schäffer;Ernst H. K. Stelzer

  • Kinesin’s tail domain is an inhibitory regulator of the motor domain

    David L. Coy;William O. Hancock;Michael Wagenbach;Jonathon Howard

  • Rigidity of microtubules is increased by stabilizing agents.

    Brian Mickey;Jonathon Howard

Frequent Co-Authors

Anthony A. Hyman
Anthony A. Hyman Max Planck Institute of Molecular Cell Biology and Genetics
Frank Jülicher
Frank Jülicher Max Planck Society
Henry Hess
Henry Hess Columbia University
Karla M. Neugebauer
Karla M. Neugebauer Yale University
A. J. Hudspeth
A. J. Hudspeth Howard Hughes Medical Institute
Stephan W. Grill
Stephan W. Grill Max Planck Society
Wolfgang Pompe
Wolfgang Pompe TU Dresden
Douglas B. Chrisey
Douglas B. Chrisey Tulane University
Alfons van Blaaderen
Alfons van Blaaderen Utrecht University

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