World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
64
Citations
12021
World Ranking
1763
National Ranking
51

Overview

Philippe Pasero is affiliated with the University of Montpellier in France, focusing on research within the broad field of Biochemistry, Genetics, and Molecular Biology. Their work spans multiple subfields, including Molecular Biology, Immunology, Cancer Research, Oncology, and Cell Biology.

The scientist's research extensively covers topics such as DNA Repair Mechanisms, Cancer Therapeutics and Mechanisms, Genomics and Chromatin Dynamics, RNA Research and Splicing, Microtubule and Mitosis Dynamics, CRISPR and Genetic Engineering, and Interferon and Immune Responses.

Pasero has contributed to the scientific community through publications in several frequent venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Molecular Cell
  • Comptes Rendus Biologies
  • The EMBO Journal

Among recent papers authored or co-authored by Pasero are:

  • Targeting the DNA damage response in immuno-oncology: developments and opportunities, 2021, Nature Reviews. Cancer
  • Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites, 2020, Nature Communications
  • Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability, 2020, Nature Communications
  • TDP-43 dysfunction results in R-loop accumulation and DNA replication defects, 2020, Journal of Cell Science
  • Ethanol exposure increases mutation rate through error-prone polymerases, 2020, Nature Communications

Their collaborative efforts include frequent co-authors such as:

  • Yea-Lih Lin
  • Jérôme Moreaux
  • Armelle Lengronne
  • Benjamin Pardo
  • Sara Ovejero

Best Publications

  • Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

    Sandie Tuduri;Sandie Tuduri;Laure Crabbé;Chiara Conti;Hélène Tourrière

  • Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing

    Nicola Crosetto;Abhishek Mitra;Maria Joao Silva;Magda Bienko;Magda Bienko

  • SAMHD1 acts at stalled replication forks to prevent interferon induction

    Flavie Coquel;Maria-Joao Silva;Maria-Joao Silva;Hervé Técher;Karina Zadorozhny

  • dNTP pools determine fork progression and origin usage under replication stress.

    Jérôme Poli;Olga Tsaponina;Laure Crabbé;Andrea Keszthelyi

  • Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations.

    Sarah Cohen;Nadine Puget;Yea-Lih Lin;Thomas Clouaire

  • Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53.

    Hélène Tourrière;Gwennaëlle Versini;Violeta Cordón-Preciado;Constance Alabert

  • ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase

    Kenji Shimada;Philippe Pasero;Susan M. Gasser

  • Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locus

    Philippe Pasero;Aaron Bensimon;Etienne Schwob

  • SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage

    Ruth Clifford;Tania Louis;Pauline Robbe;Sam Ackroyd

  • Rescuing Stalled or Damaged Replication Forks

    Joseph T.P. Yeeles;Jérôme Poli;Kenneth J. Marians;Philippe Pasero

  • Mitotic Remodeling of the Replicon and Chromosome Structure

    Jean-Marc Lemaitre;Etienne Danis;Philippe Pasero;Yegor Vassetzky

  • Monitoring S phase progression globally and locally using BrdU incorporation in TK(+) yeast strains.

    Armelle Lengronne;Philippe Pasero;Aaron Bensimon;Etienne Schwob

  • Targeting the DNA damage response in immuno-oncology: developments and opportunities.

    Roman M. Chabanon;Roman M. Chabanon;Mathieu Rouanne;Mathieu Rouanne;Christopher J. Lord;Jean-Charles Soria;Jean-Charles Soria

  • Signaling pathways of replication stress in yeast

    Benjamin Pardo;Laure Crabbé;Philippe Pasero

  • New histone supply regulates replication fork speed and PCNA unloading

    Jakob Mejlvang;Yunpeng Feng;Constance Alabert;Kai J. Neelsen

  • A role for the Cdc7 kinase regulatory subunit Dbf4p in the formation of initiation-competent origins of replication.

    Philippe Pasero;Bernard P. Duncker;Etienne Schwob;Susan M. Gasser

  • Maintenance of fork integrity at damaged DNA and natural pause sites

    Hélène Tourrière;Philippe Pasero

  • Anaphase Onset Before Complete DNA Replication with Intact Checkpoint Responses

    Jordi Torres-Rosell;Giacomo De Piccoli;Violeta Cordon-Preciado;Sarah Farmer

  • The causes of replication stress and their consequences on genome stability and cell fate.

    Indiana Magdalou;Bernard S. Lopez;Philippe Pasero;Sarah A.E. Lambert

  • Genetic and epigenetic determinants of DNA replication origins, position and activation.

    Marcel Méchali;Kazumasa Yoshida;Philippe Coulombe;Philippe Pasero

Frequent Co-Authors

Krzysztof Ginalski
Krzysztof Ginalski University of Warsaw
Susan M. Gasser
Susan M. Gasser Friedrich Miescher Institute
Monsef Benkirane
Monsef Benkirane University of Montpellier
Marcel Méchali
Marcel Méchali Centre national de la recherche scientifique, CNRS
Matthias Peter
Matthias Peter ETH Zurich
Michael Lisby
Michael Lisby University of Copenhagen
Alessandro Vindigni
Alessandro Vindigni Washington University in St. Louis
Roberto Chiarle
Roberto Chiarle Harvard University
Kay Hofmann
Kay Hofmann University of Cologne

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