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Biology and Biochemistry

D-Index
63
Citations
17943
World Ranking
10055
National Ranking
360

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Monsef Benkirane is affiliated with the University of Montpellier in France and has a research focus encompassing immunology, microbiology, medicine, biochemistry, genetics, and molecular biology. Their work spans molecular biology, immunology, virology, epidemiology, and infectious diseases, emphasizing a multidisciplinary approach.

Their main research topics include:

  • HIV Research and Treatment
  • Interferon and Immune Responses
  • Cytomegalovirus and Herpesvirus Research
  • Genomics and Chromatin Dynamics
  • HIV/AIDS Drug Development and Treatment
  • RNA Research and Splicing
  • RNA and Protein Synthesis Mechanisms

Frequent coauthors collaborating with Monsef Benkirane include:

  • Shinichi Machida
  • Suzie Thenin-Houssier
  • Lucie Bonnet-Madin
  • Heng-Chang Chen
  • Olivier Cuvier

Monsef Benkirane has published regularly in a variety of scientific venues, notably:

  • UNC Libraries
  • Proceedings of the National Academy of Sciences
  • PLoS Pathogens
  • Comptes Rendus Biologies
  • Molecular Cell

Recent publication examples include:

  • "Hair follicle stem cell replication stress drives IFI16/STING-dependent inflammation in hidradenitis suppurativa" (2020, Journal of Clinical Investigation)
  • "Exploring histone loading on HIV DNA reveals a dynamic nucleosome positioning between unintegrated and integrated viral genome" (2020, Proceedings of the National Academy of Sciences)
  • "SAMHD1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity" (2020, PLoS Pathogens)
  • "POLE3 is a repressor of unintegrated HIV-1 DNA required for efficient virus integration and escape from innate immune sensing" (2023, Science Advances)
  • "KAP1 targets actively transcribed genomic loci to exert pleomorphic effects on RNA polymerase II activity" (2020, Philosophical Transactions of the Royal Society B Biological Sciences)

Among recognitions, Monsef Benkirane is a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

    Nadine Laguette;Bijan Sobhian;Nicoletta Casartelli;Mathieu Ringeard

  • SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates.

    Hichem Lahouassa;Waaqo Daddacha;Henning Hofmann;Diana Ayinde;Diana Ayinde;Diana Ayinde

  • Suppression of MicroRNA-Silencing Pathway by HIV-1 During Virus Replication

    Robinson Triboulet;Bernard Mari;Yea-Lih Lin;Christine Chable-Bessia

  • Post-activation Turn-off of NF-κB-dependent Transcription Is Regulated by Acetylation of p65

    Rosemary E. Kiernan;Vanessa Bres;Raymond W.M. Ng;Marie-Pierre Coudart

  • Towards an HIV cure: a global scientific strategy

    Steven G Deeks;Brigitte Autran;Ben Berkhout;Monsef Benkirane

  • Evidence that HIV-1 Encodes an siRNA and a Suppressor of RNA Silencing

    Yamina Bennasser;Shu-Yun Le;Monsef Benkirane;Kuan-Teh Jeang

  • HIV-1 tat transcriptional activity is regulated by acetylation.

    Rosemary E. Kiernan;Caroline Vanhulle;Lou Schiltz;Emmanuelle Adam

  • International AIDS Society global scientific strategy: towards an HIV cure 2016

    Steven G Deeks;Sharon R Lewin;Anna Laura Ross;Jintanat Ananworanich

  • Mechanism of Transdominant Inhibition of CCR5-mediated HIV-1 Infection by ccr5Δ32

    Monsef Benkirane;Dong-Yan Jin;Rene F. Chun;Richard A. Koup

  • Selective CXCR4 antagonism by Tat: Implications for in vivo expansion of coreceptor use by HIV-1

    Hua Xiao;Christine Neuveut;H. Lee Tiffany;Monsef Benkirane

  • HIV-1 Tat Assembles a Multifunctional Transcription Elongation Complex and Stably Associates with the 7SK snRNP

    Bijan Sobhian;Nadine Laguette;Ahmad Yatim;Mirai Nakamura

  • Phosphorylation of SAMHD1 by Cyclin A2/CDK1 Regulates Its Restriction Activity toward HIV-1

    Alexandra Cribier;Benjamin Descours;Ana Luiza Chaves Valadão;Nadine Laguette

  • SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells.

    Benjamin Descours;Alexandra Cribier;Christine Chable-Bessia;Diana Ayinde

  • SAMHD1 acts at stalled replication forks to prevent interferon induction

    Flavie Coquel;Maria-Joao Silva;Maria-Joao Silva;Hervé Técher;Karina Zadorozhny

  • Activation of Integrated Provirus Requires Histone Acetyltransferase p300 AND P/CAF ARE COACTIVATORS FOR HIV-1 Tat

    Monsef Benkirane;Rene F. Chun;Hua Xiao;Vasily V. Ogryzko

  • Suv39H1 and HP1γ are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency

    Isaure du Chéné;Euguenia Basyuk;Yea-Lih Lin;Robinson Triboulet

  • Towards an HBV cure: state-of-the-art and unresolved questions—report of the ANRS workshop on HBV cure

    Mirjam B. Zeisel;Julie Lucifora;William S. Mason;Camille Sureau

  • Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA‐dependent protein kinase PKR

    Monsef Benkirane;Christine Neuveut;Rene F. Chun;Stephen M. Smith

  • NOTCH1 Nuclear Interactome Reveals Key Regulators of Its Transcriptional Activity and Oncogenic Function

    Ahmad Yatim;Clarisse Benne;Bijan Sobhian;Sabine Laurent-Chabalier

  • CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses

    Benjamin Descours;Gaël Petitjean;José-Luis López-Zaragoza;José-Luis López-Zaragoza;Timothée Bruel;Timothée Bruel

Frequent Co-Authors

Jacques Reynes
Jacques Reynes University of Montpellier
Kuan-Teh Jeang
Kuan-Teh Jeang National Institutes of Health
Olivier Schwartz
Olivier Schwartz Université Paris Cité
Carine Van Lint
Carine Van Lint Université Libre de Bruxelles
Ben Berkhout
Ben Berkhout University of Amsterdam
Bernard Mari
Bernard Mari Centre national de la recherche scientifique, CNRS
Pascal Barbry
Pascal Barbry Centre national de la recherche scientifique, CNRS
Arsène Burny
Arsène Burny Université Libre de Bruxelles
Hua Xiao
Hua Xiao Michigan State University
Philippe Pasero
Philippe Pasero Centre national de la recherche scientifique, CNRS

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