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Karlene A. Cimprich

Karlene A. Cimprich

Stanford University
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
21686
World Ranking
16918
National Ranking
6971

Karlene A. Cimprich publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Karlene A. Cimprich sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 96 publications — 4th percentile

4% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Karlene A. Cimprich D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Karlene A. Cimprich sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 51 D-Index — 14th percentile

14% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2015 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Karlene A. Cimprich is affiliated with Stanford University in the United States. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with significant contributions also in medicine. The focus of their work covers molecular biology, oncology, epidemiology, immunology, and genetics.

The scientist's research topics include:

  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering
  • RNA and protein synthesis mechanisms
  • PARP inhibition in cancer therapy
  • Immune Cell Function and Interaction
  • Cancer-related Molecular Pathways
  • Advanced biosensing and bioanalysis techniques

Recent publications by Karlene A. Cimprich reflect active work in molecular cell biology, focusing on RNA-DNA hybrid formation, genome stability, and replication stress. Selected recent papers include:

  • "R-loop-derived cytoplasmic RNA-DNA hybrids activate an immune response" (2022, Nature)
  • "Walking a tightrope: The complex balancing act of R-loops in genome stability" (2022, Molecular Cell)
  • "HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis" (2020, Molecular Cell)
  • "qDRIP: a method to quantitatively assess RNA-DNA hybrid formation genome-wide" (2020, Nucleic Acids Research)
  • "Catalytically inactive, purified RNase H1: A specific and sensitive probe for RNA-DNA hybrid imaging" (2021, The Journal of Cell Biology)

Frequent publication venues for their work include Molecular Cell, Nature, bioRxiv (Cold Spring Harbor Laboratory), Nucleic Acids Research, and The Journal of Cell Biology.

Karlene A. Cimprich collaborates regularly with several colleagues in the field, including:

  • Magdalena P. Crossley
  • Gongshi Bai
  • Ataya Sathirachinda
  • Joshua R. Brickner
  • Chenlin Song

In recognition of career achievements, Karlene A. Cimprich was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2015.

Best Publications

  • Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

    Christine E. Canman;Dae Sik Lim;Karlene A. Cimprich;Yoichi Taya

  • Causes and consequences of replication stress.

    Michelle K. Zeman;Karlene A. Cimprich

  • ATR: an essential regulator of genome integrity

    Karlene A. Cimprich;David Cortez

  • Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint

    Tony S. Byun;Marcin Pacek;Muh-ching Yee;Johannes C. Walter

  • The essential kinase ATR: ensuring faithful duplication of a challenging genome

    Joshua C. Saldivar;David Cortez;Karlene A. Cimprich

  • Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints.

    William A. Cliby;William A. Cliby;Christopher J. Roberts;Karlene A. Cimprich;Karlene A. Cimprich;Cheri M. Stringer

  • A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability

    Renee D. Paulsen;Deena V. Soni;Roy Wollman;Angela T. Hahn

  • Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses.

    Stephan Hamperl;Michael J. Bocek;Joshua C. Saldivar;Tomek Swigut

  • R-Loops as Cellular Regulators and Genomic Threats.

    Madzia P. Crossley;Michael Bocek;Karlene A. Cimprich

  • Transcription-Coupled Nucleotide Excision Repair Factors Promote R-Loop-Induced Genome Instability

    Julie Sollier;Caroline Townsend Stork;María L. García-Rubio;Renee D. Paulsen

  • Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells

    Gaelen T Hess;Laure Frésard;Kyuho Han;Cameron H Lee

  • An ATR- and Cdc7-Dependent DNA Damage Checkpoint that Inhibits Initiation of DNA Replication

    Vincenzo Costanzo;David Shechter;Patrick J Lupardus;Karlene A Cimprich

  • ATR phosphorylates SMARCAL1 to prevent replication fork collapse

    Frank B. Couch;Carol E. Bansbach;Robert Driscoll;Jessica W. Luzwick

  • Breaking bad: R-loops and genome integrity

    Julie Sollier;Karlene A. Cimprich

  • cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein

    Karlene A. Cimprich;Tae Bum Shin;Curtis T. Keith;Stuart L. Schreiber

  • The ATR pathway: fine-tuning the fork.

    Renee D Paulsen;Karlene A Cimprich

  • The structural determinants of checkpoint activation

    Christina A. MacDougall;Tony S. Byun;Christopher Van;Muh-ching Yee

  • The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability

    Stephan Hamperl;Karlene A. Cimprich

  • Conflict Resolution in the Genome: How Transcription and Replication Make It Work

    Stephan Hamperl;Karlene A. Cimprich

  • Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage

    Caroline Townsend Stork;Michael Bocek;Madzia P Crossley;Julie Sollier

Frequent Co-Authors

David Cortez
David Cortez Vanderbilt University
Tobias Meyer
Tobias Meyer Stanford University
Thomas J. Wandless
Thomas J. Wandless Stanford University
Frédéric Chédin
Frédéric Chédin University of California, Davis
Johannes C. Walter
Johannes C. Walter Harvard University
Rachel H. Giles
Rachel H. Giles Utrecht University
Vincenzo Costanzo
Vincenzo Costanzo University of Catania
Stuart L. Schreiber
Stuart L. Schreiber Harvard University
Jean Gautier
Jean Gautier Columbia University
William A. Cliby
William A. Cliby Mayo Clinic

External Links

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