Rafael Fridman

Overview

Best Publications

• A Highly Specific Inhibitor of Matrix Metalloproteinase-9 Rescues Laminin from Proteolysis and Neurons from Apoptosis in Transient Focal Cerebral Ischemia

  Zezong Gu;Jiankun Cui;Stephen Brown;Rafael Fridman

  565
  Citations

• Discoidin domain receptor tyrosine kinases: new players in cancer progression.

  Rajeshwari R. Valiathan;Marta Marco;Birgit Leitinger;Celina G. Kleer

  405
  Citations

• Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro

  H. William Schnaper;H. William Schnaper;Derrick S. Grant;William G. Stetler-Stevenson;Rafael Fridman

  363
  Citations

• Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and -9.

  Josiah Ochieng;Rafael Fridman;Pratima Nangia-Makker;David E. Kleiner

  330
  Citations

• Interaction of endothelial cells with a laminin A chain peptide (SIKVAV) in vitro and induction of angiogenic behavior in vivo.

  Derrick S. Grant;James L. Kinsella;Rafael Fridman;Robert Auerbach

  292
  Citations

• Domain structure of human 72-kDa gelatinase/Type IV collagenase: Characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase-2 (TIMP-2) binding regions

  Rafael Fridman;Thomas R. Fuerst;Robert E. Bird;Matti Hoyhtya

  289
  Citations

• Processing, shedding, and endocytosis of membrane type 1-matrix metalloproteinase (MT1-MMP).

  Pamela Osenkowski;Marta Toth;Rafael Fridman

  273
  Citations

• Pro-MMP-9 activation by the MT1-MMP/MMP-2 axis and MMP-3: role of TIMP-2 and plasma membranes.

  Marta Toth;Irina Chvyrkova;M.Margarida Bernardo;Sonia Hernandez-Barrantes

  250
  Citations

• MMP-2 colocalizes with caveolae on the surface of endothelial cells.

  Alain Puyraimond;Rafael Fridman;Monique Lemesle;Brigitte Arbeille

  245
  Citations

• Tissue inhibitor of metalloproteinase-1 protects human breast epithelial cells against intrinsic apoptotic cell death via the focal adhesion kinase/phosphatidylinositol 3-kinase and MAPK signaling pathway.

  Xu Wen Liu;M. Margarida Bernardo;Rafael Fridman;Hyeong Reh Choi Kim

  244
  Citations

• TIMP-2 (tissue inhibitor of metalloproteinase-2) regulates MMP-2 (matrix metalloproteinase-2) activity in the extracellular environment after pro-MMP-2 activation by MT1 (membrane type 1)-MMP.

  M Margarida Bernardo;Rafael Fridman

  243
  Citations

• Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence

  Daniel W. Visscher;Matti Höyhtyä;Susan K. Ottosen;Chi‐Ming ‐M Liang

  239
  Citations

• Regulation of membrane type-matrix metalloproteinases.

  Sonia Hernandez-Barrantes;Margarida Bernardo;Marta Toth;Rafael Fridman

  219
  Citations

• Cell surface association of matrix metalloproteinase-9 (gelatinase B)

  Rafael Fridman;Marta Toth;Irina Chvyrkova;Samy O. Meroueh

  216
  Citations

• Characterization of the Monomeric and Dimeric Forms of Latent and Active Matrix Metalloproteinase-9 DIFFERENTIAL RATES FOR ACTIVATION BY STROMELYSIN 1

  Matthew W. Olson;M. Margarida Bernardo;Martin Pietila;David C. Gervasi

  214
  Citations

• Differential inhibition of membrane type 3 (MT3)-matrix metalloproteinase (MMP) and MT1-MMP by tissue inhibitor of metalloproteinase (TIMP)-2 and TIMP-3 regulates pro-MMP-2 activation

  Huiren Zhao;M. Margarida Bernardo;Pamela Osenkowski;Anjum Sohail

  205
  Citations

• High Affinity Binding of Latent Matrix Metalloproteinase-9 to the α2(IV) Chain of Collagen IV

  Matthew W. Olson;Marta Toth;David C. Gervasi;Yoshikazu Sado

  201
  Citations

• Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergistically with synthetic matrix metalloproteinase (MMP) inhibitors but not with TIMP-4 to enhance the (Membrane type 1)-MMP-dependent activation of pro-MMP-2.

  Marta Toth;M. Margarida Bernardo;David C. Gervasi;Paul D. Soloway

  199
  Citations

• Maspin expression inhibits osteolysis, tumor growth, and angiogenesis in a model of prostate cancer bone metastasis.

  Michael L. Cher;Hector R. Biliran;Sunita Bhagat;Yonghong Meng

  199
  Citations

• Proteolysis of Aβ Peptide from Alzheimer Disease Brain by Gelatinase A

  A.E. Roher;T.C. Kasunic;A.S. Woods;R.J. Cotter

  189
  Citations