D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 73 Citations 19,139 183 World Ranking 2518 National Ranking 1342

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

Bonnie F. Sloane mostly deals with Cathepsin B, Cathepsin S, Cathepsin, Cell biology and Cancer research. In his research, Annexin A2 is intimately related to Molecular biology, which falls under the overarching field of Cathepsin B. His Cathepsin S study deals with the bigger picture of Cathepsin D.

His biological study spans a wide range of topics, including Extracellular matrix, Cysteine and Proteolysis. His Cell biology research is multidisciplinary, incorporating perspectives in Proteases, Secretion, Cell culture and Angiogenesis. His Cancer research research includes themes of Immunohistochemistry and Metastasis.

His most cited work include:

  • Cysteine cathepsins: multifunctional enzymes in cancer (980 citations)
  • Acidity generated by the tumor microenvironment drives local invasion (645 citations)
  • Unraveling the role of proteases in cancer. (472 citations)

What are the main themes of his work throughout his whole career to date?

Bonnie F. Sloane mainly investigates Cathepsin B, Cancer research, Molecular biology, Cathepsin and Cell biology. Much of his study explores Cathepsin B relationship to Cathepsin D. His Cancer research research is multidisciplinary, relying on both Cancer, Breast cancer, Metastasis and Pathology.

The Molecular biology study combines topics in areas such as Gene expression, Cystatin and Transfection. His research in Cathepsin intersects with topics in Cell culture, Cysteine and Secretion. His work carried out in the field of Cell biology brings together such families of science as Proteases, Protease and Proteolysis.

He most often published in these fields:

  • Cathepsin B (44.18%)
  • Cancer research (31.73%)
  • Molecular biology (26.51%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cancer research (31.73%)
  • Tumor microenvironment (13.65%)
  • Breast cancer (12.05%)

In recent papers he was focusing on the following fields of study:

Cancer research, Tumor microenvironment, Breast cancer, Cancer and Metastasis are his primary areas of study. His Cancer research study combines topics from a wide range of disciplines, such as Immunohistochemistry, Immunology, Cancer cell, Phenotype and Breast carcinoma. The various areas that Bonnie F. Sloane examines in his Tumor microenvironment study include Cell type, Pathology, Inflammatory breast cancer, Cell biology and Myoepithelial cell.

His Cancer research includes elements of Protease and Live cell imaging. His research integrates issues of Proteases, Molecular biology, Cathepsin B and Paracrine signalling in his study of Metastasis. Bonnie F. Sloane interconnects Cathepsin D and Cysteine protease in the investigation of issues within Cathepsin B.

Between 2012 and 2021, his most popular works were:

  • Acidity generated by the tumor microenvironment drives local invasion (645 citations)
  • Cathepsin B: multiple roles in cancer. (153 citations)
  • Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progression (68 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

Bonnie F. Sloane mostly deals with Cancer research, Cathepsin B, Metastasis, Pathology and Breast cancer. His Cancer research research focuses on Cancer and how it connects with Protein degradation, Macrophage and Signal transduction. His Cathepsin B study combines topics in areas such as Carcinogenesis, Molecular biology, Cathepsin and Proteases.

His study focuses on the intersection of Metastasis and fields such as Immunology with connections in the field of Paracrine signalling. His work deals with themes such as Tumor microenvironment, Ductal carcinoma and Transdifferentiation, which intersect with Pathology. His Cathepsin C research incorporates themes from Cathepsin S, Cathepsin L1, Cathepsin E, Cathepsin A and Cathepsin H.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Cysteine cathepsins: multifunctional enzymes in cancer

Mona Mostafa Mohamed;Bonnie F. Sloane.
Nature Reviews Cancer (2006)

1526 Citations

Acidity generated by the tumor microenvironment drives local invasion

Veronica Estrella;Tingan Chen;Mark Lloyd;Jonathan Wojtkowiak.
Cancer Research (2013)

877 Citations

Unraveling the role of proteases in cancer.

Jennifer E Koblinski;Mamoun Ahram;Bonnie F Sloane.
Clinica Chimica Acta (2000)

719 Citations

Bicarbonate increases tumor pH and inhibits spontaneous metastases

Ian F. Robey;Brenda K. Baggett;Nathaniel D. Kirkpatrick;Denise J. Roe.
Cancer Research (2009)

611 Citations

Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues.

M R Buck;D G Karustis;N A Day;K V Honn.
Biochemical Journal (1992)

493 Citations

Lysosomal cathepsin B: correlation with metastatic potential.

Bonnie F. Sloane;John R. Dunn;Kenneth V. Honn.
Science (1981)

450 Citations

Pericellular pH Affects Distribution and Secretion of Cathepsin B in Malignant Cells

Jurij Rozhin;Mansoureh Sameni;Grace Ziegler;Bonnie F. Sloane.
Cancer Research (1994)

394 Citations

Cysteine cathepsins in human cancer.

Christopher Jedeszko;Bonnie F Sloane.
Biological Chemistry (2004)

359 Citations

Dynamic imaging of protease activity with fluorescently quenched activity-based probes

Galia Blum;Stefanie R Mullins;Kinneret Keren;Marko Fonovic;Marko Fonovic.
Nature Chemical Biology (2005)

346 Citations

Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples.

Michael R. Emmert-Buck;Mark J. Roth;Zhenping Zhuang;Elias Campo.
American Journal of Pathology (1994)

295 Citations

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