D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 66 Citations 17,679 202 World Ranking 5496 National Ranking 395

Overview

What is he best known for?

The fields of study Thomas Reinheckel is best known for:

  • Gene
  • Enzyme
  • Apoptosis

His research on Biochemistry frequently links to adjacent areas such as In vitro. In vitro and Biochemistry are commonly linked in his work. Thomas Reinheckel integrates Enzyme and Cytosol in his research. Thomas Reinheckel connects Cathepsin with Lysosome in his research. He undertakes multidisciplinary studies into Lysosome and Cathepsin in his work. His work often combines Cell biology and Molecular biology studies. While working on this project, Thomas Reinheckel studies both Molecular biology and Cell biology. He conducted interdisciplinary study in his works that combined Internal medicine and Endocrinology. His study deals with a combination of Endocrinology and Internal medicine.

His most cited work include:

  • The NALP3 inflammasome is involved in the innate immune response to amyloid-β (1928 citations)
  • Degradation of oxidized proteins in mammalian cells (796 citations)
  • Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis (495 citations)

What are the main themes of his work throughout his whole career to date

Cathepsin L, Cathepsin S and Cathepsin H are the main areas of his Cathepsin studies. He integrates several fields in his works, including Cathepsin S and Cathepsin B. In his work, Thomas Reinheckel performs multidisciplinary research in Cathepsin B and Cathepsin D. He incorporates Cathepsin D and Cathepsin in his research. His work on Oxidative stress expands to the thematically related Biochemistry. His study ties his expertise on Biochemistry together with the subject of Oxidative stress. Borrowing concepts from Proteases, Thomas Reinheckel weaves in ideas under Enzyme. In his research, he undertakes multidisciplinary study on Cell biology and Immunology. In his study, he carries out multidisciplinary Immunology and Cell biology research.

Thomas Reinheckel most often published in these fields:

  • Biochemistry (83.64%)
  • Enzyme (72.73%)
  • Cell biology (51.52%)

What were the highlights of his more recent work (between 2019-2022)?

  • Cell biology (81.82%)
  • Biochemistry (72.73%)
  • Enzyme (72.73%)

In recent works Thomas Reinheckel was focusing on the following fields of study:

As part of his studies on Cell biology, Thomas Reinheckel frequently links adjacent subjects like Organoid. His Organoid study frequently draws connections to adjacent fields such as Cell biology. Many of his studies on Biochemistry apply to Proteases as well. He combines Enzyme and Glycosylation in his research. In his research, he performs multidisciplinary study on Glycosylation and Enzyme. Thomas Reinheckel performs multidisciplinary study on Genetics and Mutant in his works. Thomas Reinheckel performs multidisciplinary study in the fields of Cathepsin B and Lysosome via his papers. In his works, Thomas Reinheckel performs multidisciplinary study on Lysosome and Cathepsin B. In his works, he performs multidisciplinary study on Gene and Biomarker.

Between 2019 and 2022, his most popular works were:

  • Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation (42 citations)
  • Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling (29 citations)
  • A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment (17 citations)

In his most recent research, the most cited works focused on:

  • Gene
  • Cancer
  • Enzyme

Thomas Reinheckel incorporates Cell biology and DNA in his research. He undertakes multidisciplinary studies into DNA and Cell biology in his work. His study deals with a combination of Enzyme and Extracellular matrix. With his scientific publications, his incorporates both Extracellular matrix and Cathepsin. Thomas Reinheckel incorporates Cathepsin and Cathepsin D in his research. Cathepsin D is often connected to Enzyme in his work. His Biochemistry study typically links adjacent topics like Matricellular protein. Matricellular protein and Biochemistry are commonly linked in his work. In his works, Thomas Reinheckel undertakes multidisciplinary study on Breast cancer and Triple-negative breast cancer.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.

Annett Halle;Veit Hornung;Gabor C Petzold;Cameron R Stewart.
Nature Immunology (2008)

2321 Citations

Degradation of oxidized proteins in mammalian cells.

Tilman Grune;Thomas Reinheckel;Kelvin J. A. Davies.
The FASEB Journal (1997)

994 Citations

Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

Walter Halangk;Markus M. Lerch;Barbara Brandt-Nedelev;Wera Roth.
Journal of Clinical Investigation (2000)

692 Citations

Distinct roles for cysteine cathepsin genes in multistage tumorigenesis

Vasilena Gocheva;Wei Zeng;Danxia Ke;David Klimstra.
Genes & Development (2006)

562 Citations

Specialized roles for cysteine cathepsins in health and disease

Jochen Reiser;Brian Adair;Thomas Reinheckel.
Journal of Clinical Investigation (2010)

526 Citations

Emerging roles of cysteine cathepsins in disease and their potential as drug targets.

Olga Vasiljeva;Thomas Reinheckel;Christoph Peters;Dusan Turk.
Current Pharmaceutical Design (2007)

499 Citations

Comparative resistance of the 20S and 26S proteasome to oxidative stress.

Thomas Reinheckel;Nicolle Sitte;Oliver Ullrich;Ulrike Kuckelkorn.
Biochemical Journal (1998)

478 Citations

Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome.

Tilman Grune;Thomas Reinheckel;Minakshi Joshi;Kelvin J.A. Davies.
Journal of Biological Chemistry (1995)

458 Citations

Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation

M. Kathryn Liszewski;Martin Kolev;Gaelle Le Friec;Marilyn Leung.
Immunity (2013)

416 Citations

Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment

Georgy Mikhaylov;Ursa Mikac;Anna A. Magaeva;Volya I. Itin.
Nature Nanotechnology (2011)

408 Citations

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