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Melanie Boerries

Melanie Boerries

D-Index & Metrics

Molecular Biology

D-Index
56
Citations
9802
World Ranking
2215
National Ranking
149

Overview

Melanie Boerries is affiliated with the University of Freiburg in Germany. Their research focuses primarily on molecular biology, oncology, immunology, and cancer research, spanning a broad range of topics related to cancer genomics and diagnostics, immune cell function and interaction, cancer cells and metastasis, immune cells in cancer, cancer immunotherapy and biomarkers, pancreatic and hepatic oncology research, and acute myeloid leukemia research.

Boerries has authored numerous publications, with recurring contributions in several prominent scientific journals. Frequent publication venues include Blood, bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Nature Communications, and Cancers. These venues reflect a consistent engagement with cancer biology and immunological aspects of disease.

Frequent collaborators with Boerries include Geoffroy Andrieux, Anna Lena Illert, Justus Duyster, Robert Zeiser, and Patrick Metzger, indicating a network of coauthors with whom multiple studies and projects have been conducted. Their collaborations span across different areas of biomedical research, particularly those involving cancer and immune system studies.

Notable recent papers authored or coauthored by Boerries are:

  • Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma, 2022, Cancer Cell
  • Spatially confined sub-tumor microenvironments in pancreatic cancer, 2021, Cell
  • T-cell dysfunction in the glioblastoma microenvironment is mediated by myeloid cells releasing interleukin-10, 2022, Nature Communications
  • Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers, 2021, Cancer Discovery
  • HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice, 2020, Nature Communications

Their research integrates molecular and cellular insights to address tumor microenvironments, immune regulation in cancer, and genomic and transcriptomic analyses to guide therapeutic decisions. This multidisciplinary approach aligns with their extensive work in both biochemistry, genetics, and molecular biology as well as medicine, reflecting a broad expert domain.

Best Publications

  • The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

    Angela M. Krebs;Julia Mitschke;María Lasierra Losada;Otto Schmalhofer

  • Spatially confined sub-tumor microenvironments in pancreatic cancer.

    Barbara T. Grünwald;Antoine Devisme;Geoffroy Andrieux;Foram Vyas

  • Cardiac adenoviral S100A1 gene delivery rescues failing myocardium

    Patrick Most;Sven T. Pleger;Mirko Völkers;Beatrix Heidt

  • Oncogenic JAK2 V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms

    Alessandro Prestipino;Alica J. Emhardt;Konrad Aumann;David O’Sullivan

  • Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers

    Peter Horak;Christoph Heining;Simon Kreutzfeldt;Barbara Hutter

  • HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice.

    Rouven Hoefflin;Sabine Harlander;Silvia Schäfer;Patrick Metzger

  • Conformation-specific antibodies reveal distinct actin structures in the nucleus and the cytoplasm.

    C.-A. Schoenenberger;S. Buchmeier;M. Boerries;R. Sütterlin

  • Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks

    Melanie Boerries;Florian Grahammer;Sven Eiselein;Moritz Buck

  • Combination of Lenvatinib and Pembrolizumab Is an Effective Treatment Option for Anaplastic and Poorly Differentiated Thyroid Carcinoma.

    Christine Dierks;Christine Dierks;Jochen Seufert;Konrad Aumann;Juri Ruf

  • From a Traditional Medicinal Plant to a Rational Drug: Understanding the Clinically Proven Wound Healing Efficacy of Birch Bark Extract

    Sandra Ebeling;Katrin Naumann;Simone Pollok;Tina Wardecki

  • Quantitative evaluation of chromosomal rearrangements in gene-edited human stem cells by CAST-Seq.

    Giandomenico Turchiano;Geoffroy Andrieux;Geoffroy Andrieux;Julia Klermund;Georges Blattner

  • The expansion of human T-bet high CD21 low B cells is T cell dependent

    Baerbel Keller;Valentina Strohmeier;Valentina Strohmeier;Ina Harder;Susanne Unger

  • Ca2+-Dependent Interaction of S100A1 with F1-ATPase Leads to an Increased ATP Content in Cardiomyocytes

    Melanie Boerries;Patrick Most;Patrick Most;Jonathan R. Gledhill;John E. Walker

  • Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation

    Shaima’A Hamarsheh;Lena Osswald;Benedikt S. Saller;Benedikt S. Saller;Susanne Unger

  • RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia

    Daniel B Lipka;Daniel B Lipka;Tania Witte;Reka Toth;Jing Yang

  • Variant classification in precision oncology.

    Jonas Leichsenring;Peter Horak;Simon Kreutzfeldt;Christoph Heining

  • Constitutional SAMD9L mutations cause familial myelodysplastic syndrome and transient monosomy 7.

    Victor B. Pastor;Sushree S. Sahoo;Jessica Boklan;Georg C. Schwabe

  • mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress

    Florian Grahammer;Nora Haenisch;Frederic Steinhardt;Lukas Sandner

  • Extracellular S100A1 Protein Inhibits Apoptosis in Ventricular Cardiomyocytes via Activation of the Extracellular Signal-regulated Protein Kinase 1/2 (ERK1/2)

    Patrick Most;Melanie Boerries;Carmen Eicher;Christopher Schweda

  • Spatially Resolved Multi-Omics Deciphers Bidirectional Tumor-Host Interdependence in Glioblastoma

    Vidhya Ravi;Paulina Will;Jan Kueckelhaus;Na Sun

Frequent Co-Authors

Robert Zeiser
Robert Zeiser University of Freiburg
Marie Follo
Marie Follo University of Freiburg
Dietmar Pfeifer
Dietmar Pfeifer University of Freiburg
Charlotte M. Niemeyer
Charlotte M. Niemeyer University of Freiburg
Tobias B. Huber
Tobias B. Huber Universität Hamburg
Hugo A. Katus
Hugo A. Katus Heidelberg University
Peter Schirmacher
Peter Schirmacher University Hospital Heidelberg
Thomas Kislinger
Thomas Kislinger University of Toronto
Thomas Reinheckel
Thomas Reinheckel University of Freiburg
Rama Khokha
Rama Khokha Princess Margaret Cancer Centre

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