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Molecular Biology

D-Index
55
Citations
16096
World Ranking
2248
National Ranking
152

Overview

Dietmar Pfeifer is affiliated with the University of Freiburg in Germany and focuses primarily on research within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans multiple subfields including Molecular Biology, Hematology, Immunology, Genetics, and Oncology.

The scientist's recent published papers highlight a range of topics related to immunology, hematology, and cellular biology. Key works include:

  • Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation, 2020, Nature Communications
  • Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans, 2020, Blood
  • Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling, 2020, Nature Communications
  • Bile acids regulate intestinal antigen presentation and reduce graft-versus-host disease without impairing the graft-versus-leukemia effect, 2020, Haematologica
  • Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation, 2022, Blood

Frequent co-authors collaborating with Dietmar Pfeifer include Geoffroy Andrieux, Justus Duyster, Robert Zeiser, Melanie Boerries, and Michael Lübbert. This collaboration network indicates a multidisciplinary approach crossing immunology, molecular biology, and clinical research.

The scientist's work has been published predominantly in venues recognized for hematology and molecular biology research. The most frequent publication venues are Blood, Nature Communications, Clinical Epigenetics, bioRxiv (Cold Spring Harbor Laboratory), and Haematologica.

The main research topics explored by Dietmar Pfeifer include:

  • Acute Myeloid Leukemia Research
  • Immune cells in cancer
  • Immune Cell Function and Interaction
  • Hematopoietic Stem Cell Transplantation
  • CAR-T cell therapy research
  • Cancer Genomics and Diagnostics
  • Myeloproliferative Neoplasms: Diagnosis and Treatment

Best Publications

  • Inflammatory bowel disease and mutations affecting the interleukin-10 receptor.

    Erik-Oliver Glocker;Daniel Kotlarz;Kaan Boztug;E. Michael Gertz

  • Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages.

    Christoph S.N. Klose;Christoph S.N. Klose;Melanie Flach;Melanie Flach;Luisa Möhle;Leif Rogell;Leif Rogell;Leif Rogell

  • The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells.

    Thomas Hoyler;Christoph S.N. Klose;Abdallah Souabni;Adriana Turqueti-Neves

  • New member of the winged-helix protein family disrupted in mouse and rat nude mutations

    Michael Nehls;Dietmar Pfeifer;Michael Schorpp;Hans Hedrich;Hans Hedrich

  • A Homozygous CARD9 Mutation in a Family with Susceptibility to Fungal Infections

    Erik-Oliver Glocker;Andre Hennigs;Mohammad Nabavi;Alejandro A. Schäffer

  • Deleterious Mutations in LRBA Are Associated with a Syndrome of Immune Deficiency and Autoimmunity

    Gabriela Lopez-Herrera;Giacomo Tampella;Qiang Pan-Hammarström;Peer Herholz

  • Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome

    Karin R. Engelhardt;Sean McGhee;Sabine Winkler;Atfa Sassi

  • Loss of interleukin-10 signaling and infantile inflammatory bowel disease: implications for diagnosis and therapy.

    Daniel Kotlarz;Daniel Kotlarz;Rita Beier;Dhaarini Murugan;Dhaarini Murugan;Jana Diestelhorst;Jana Diestelhorst

  • The phenotype of human STK4 deficiency

    Hengameh Abdollahpour;Giridharan Appaswamy;Daniel Kotlarz;Daniel Kotlarz;Jana Diestelhorst;Jana Diestelhorst

  • Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

    Nimitha R Mathew;Nimitha R Mathew;Francis Baumgartner;Lukas Braun;David O'Sullivan

  • Genome-wide analysis of DNA copy number changes and LOH in CLL using high-density SNP arrays.

    Dietmar Pfeifer;Milena Pantic;Ilona Skatulla;Justyna Rawluk

  • Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome

    Daniel Kotlarz;Natalia Ziętara;Gulbu Uzel;Thomas Weidemann

  • Campomelic Dysplasia Translocation Breakpoints Are Scattered over 1 Mb Proximal to SOX9: Evidence for an Extended Control Region

    Dietmar Pfeifer;Ralf Kist;Ken Dewar;Keri Devon

  • Oncogenic JAK2 V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms

    Alessandro Prestipino;Alica J. Emhardt;Konrad Aumann;David O’Sullivan

  • Spleen Tyrosine Kinase Is Overexpressed and Represents a Potential Therapeutic Target in Chronic Lymphocytic Leukemia

    Maike Buchner;Simon Fuchs;Gabriele Prinz;Dietmar Pfeifer

  • Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels.

    Atfa Sassi;Sandra Lazaroski;Gang Wu;Stuart M. Haslam

  • The DNA demethylating agent 5-aza-2'-deoxycytidine induces expression of NY-ESO-1 and other cancer/testis antigens in myeloid leukemia cells.

    Maika Almstedt;Nadja Blagitko-Dorfs;Jesús Duque-Afonso;Julia Karbach

  • The IL-33/ST2 axis augments effector T-cell responses during acute GVHD.

    Dawn K. Reichenbach;Vincent Schwarze;Benjamin M. Matta;Victor Tkachev

  • The SOX10/Sox10 gene from human and mouse: sequence, expression, and transactivation by the encoded HMG domain transcription factor.

    C. Pusch;Elisabeth Hustert;Dietmar Pfeifer;Peter Südbeck

  • Silencing of TGFβ signalling in microglia results in impaired homeostasis.

    Tanja Zöller;Artur Schneider;Christian Kleimeyer;Takahiro Masuda

Frequent Co-Authors

Robert Zeiser
Robert Zeiser University of Freiburg
Michael Lübbert
Michael Lübbert University of Freiburg
Marie Follo
Marie Follo University of Freiburg
Bodo Grimbacher
Bodo Grimbacher University of Freiburg
Jürgen Finke
Jürgen Finke University of Freiburg
Melanie Boerries
Melanie Boerries University of Freiburg
Alejandro A. Schäffer
Alejandro A. Schäffer National Institutes of Health
Ulrich Salzer
Ulrich Salzer University of Freiburg
Marco Prinz
Marco Prinz University of Freiburg
Bruce R. Blazar
Bruce R. Blazar University of Minnesota

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