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Immunology

D-Index
78
Citations
21104
World Ranking
1756
National Ranking
14

Overview

Rui Sun is affiliated with the University of Science and Technology of China. Their research primarily covers areas within medicine, immunology and microbiology, and biochemistry, genetics, and molecular biology. The main subfields of their scientific work include immunology, molecular biology, oncology, epidemiology, and infectious diseases.

Their work spans key topics such as immune cell function and interaction, immunotherapy and immune responses, CAR-T cell therapy research, T-cell and B-cell immunology, IL-33, ST2, and ILC pathways, immune cells in cancer, and cancer immunotherapy and biomarkers.

Prominent recent papers by Rui Sun include:

  • Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients (2020, National Science Review)
  • Aberrant pathogenic GM-CSF+T cells and inflammatory CD14+CD16+monocytes in severe pulmonary syndrome patients of a new coronavirus (2020, bioRxiv [Cold Spring Harbor Laboratory])
  • METTL3-mediated m6A RNA methylation promotes the anti-tumour immunity of natural killer cells (2021, Nature Communications)
  • Pyroptotic macrophages stimulate the SARS-CoV-2-associated cytokine storm (2021, Cellular and Molecular Immunology)
  • Liver type 1 innate lymphoid cells develop locally via an interferon-γ-dependent loop (2021, Science)

Rui Sun has frequently published in venues such as Nature Communications, Frontiers in Immunology, bioRxiv (Cold Spring Harbor Laboratory), Cancer Biology and Medicine, and SSRN Electronic Journal.

Collaborations have been significant in Rui Sun's career, with frequent co-authors including Zhigang Tian, Haiming Wei, Binqing Fu, Haoyu Sun, and Xiaohu Zheng.

Best Publications

  • Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients

    Yonggang Zhou;Binqing Fu;Xiaohu Zheng;Dongsheng Wang

  • Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity.

    Qing Zhang;Jiacheng Bi;Xiaodong Zheng;Yongyan Chen

  • NK cell-based immunotherapy for malignant diseases

    Min Cheng;Yongyan Chen;Weihua Xiao;Rui Sun

  • Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners

    Svetlana Radaeva;Rui Sun;Barbara Jaruga;Van T. Nguyen

  • Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation.

    Svetlana Radaeva;Rui Sun;Hong-na Pan;Feng Hong

  • Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell–dependent inflammation

    Jian Wang;Fengqi Li;Haiming Wei;Zhe-Xiong Lian

  • Liver-resident NK cells confer adaptive immunity in skin-contact inflammation.

    Hui Peng;Xiaojun Jiang;Yonglin Chen;Dorothy K. Sojka

  • Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression

    Jingjing Cong;Xianwei Wang;Xiaohu Zheng;Dong Wang

  • Impaired natural killer (NK) cell activity in leptin receptor deficient mice: leptin as a critical regulator in NK cell development and activation.

    Zhigang Tian;Rui Sun;Rui Sun;Rui Sun;Haiming Wei;Haiming Wei;Bin Gao

  • Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors

    Binqing Fu;Yonggang Zhou;Xiang Ni;Xianhong Tong

  • Natural Killer Cells Promote Immune Tolerance by Regulating Inflammatory TH17 Cells at the Human Maternal-Fetal Interface

    Binqing Fu;Xian Chang Li;Xian Chang Li;Rui Sun;Xianhong Tong

  • Mitochondrial fragmentation limits NK cell-based tumor immunosurveillance.

    Xiaohu Zheng;Yeben Qian;Binqing Fu;Defeng Jiao

  • High NKG2A expression contributes to NK cell exhaustion and predicts a poor prognosis of patients with liver cancer.

    Cheng Sun;Jing Xu;Qiang Huang;Mei Huang

  • Expression of leptin receptors and response to leptin stimulation of human natural killer cell lines

    Yueran Zhao;Rui Sun;Rui Sun;Li You;Chunyi Gao

  • Human CD96 Correlates to Natural Killer Cell Exhaustion and Predicts the Prognosis of Human Hepatocellular Carcinoma.

    Haoyu Sun;Qiang Huang;Mei Huang;Hao Wen

  • Aberrant pathogenic GM-CSF+ T cells and inflammatory CD14+CD16+ monocytes in severe pulmonary syndrome patients of a new coronavirus

    Yonggang Zhou;Binqing Fu;Xiaohu Zheng;Dongsheng Wang

  • Bacterial colonization dampens influenza-mediated acute lung injury via induction of M2 alveolar macrophages

    Jian Wang;Fengqi Li;Rui Sun;Xiang Gao

  • Negative regulation of liver regeneration by innate immunity (natural killer cells/interferon-γ)

    Rui Sun;Bin Gao

  • CD11b and CD27 reflect distinct population and functional specialization in human natural killer cells.

    Binqing Fu;Fuyan Wang;Rui Sun;Bin Ling

  • High-mobility group box 1 (HMGB1)-Toll-like receptor (TLR)4-interleukin (IL)-23-IL-17A axis in drug-induced damage-associated lethal hepatitis: Interaction of γδ T cells with macrophages.

    Xuefu Wang;Rui Sun;Haiming Wei;Zhigang Tian

  • TGF-β1 Down-Regulation of NKG2D/DAP10 and 2B4/SAP Expression on Human NK Cells Contributes to HBV Persistence

    Cheng Sun;Binqing Fu;Yufeng Gao;Xiaofeng Liao

  • The roles of innate immune cells in liver injury and regeneration.

    Zhongjun Dong;Haiming Wei;Rui Sun;Zhigang Tian

Frequent Co-Authors

Zhigang Tian
Zhigang Tian University of Science and Technology of China
Haiming Wei
Haiming Wei University of Science and Technology of China
Xiang Gao
Xiang Gao Nanjing University
Xian Chang Li
Xian Chang Li Cornell University
Zhe-Xiong Lian
Zhe-Xiong Lian University of Science and Technology of China
Wayne M. Yokoyama
Wayne M. Yokoyama Washington University in St. Louis
Yuzhang Wu
Yuzhang Wu Third Military Medical University
Nan Shen
Nan Shen Shanghai Jiao Tong University
Xiu-Wu Bian
Xiu-Wu Bian Third Military Medical University
Lanjuan Li
Lanjuan Li Zhejiang University

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