2022 - Research.com Biology and Biochemistry in Slovenia Leader Award
Member of the European Academy of Sciences and Arts
The scientist’s investigation covers issues in Cathepsin, Cathepsin B, Molecular biology, Biochemistry and Cystatin. Janko Kos interconnects Cancer, Cancer research, Endogeny and Cell biology in the investigation of issues within Cathepsin. His Cathepsin B study integrates concerns from other disciplines, such as Cathepsin L and Pathology.
His Molecular biology research integrates issues from Cell culture, Cathepsin O, Cathepsin H, Cathepsin D and Apoptosis. His Biochemistry research focuses on Stereochemistry and how it connects with Recombinant DNA, Protein secondary structure, Turn and Mutant. His study in Cystatin is interdisciplinary in nature, drawing from both Proteases, Cysteine, Enzyme inhibitor and PLGA.
His primary areas of investigation include Cathepsin, Molecular biology, Biochemistry, Cathepsin B and Cell biology. He studies Cathepsin, namely Cathepsin S. His studies in Molecular biology integrate themes in fields like Cathepsin D, Cystatin A, Gene and Antibody, Monoclonal antibody.
His work deals with themes such as Cathepsin L and Pathology, which intersect with Cathepsin B. His Cell biology research incorporates elements of Cytotoxic T cell, Integrin, Immune system and Jurkat cells. His biological study spans a wide range of topics, including Cancer and Metastasis.
Janko Kos mainly investigates Cathepsin, Biochemistry, Cancer research, Cytotoxicity and Butyrylcholinesterase. His Cathepsin study incorporates themes from Cystatin, Molecular biology, Perforin, Granzyme and Stem cell. His Biochemistry research is multidisciplinary, incorporating perspectives in Chelation and Cell culture.
The various areas that he examines in his Cancer research study include Subventricular zone, Cell, Cellular localization and Immune system. His research integrates issues of Cancer stem cell, Cancer and Metastasis in his study of Immune system. Janko Kos regularly links together related areas like Nitroxoline in his Cathepsin B studies.
His scientific interests lie mostly in Immune system, Butyrylcholinesterase, Cathepsin, Cancer and Cancer research. While the research belongs to areas of Immune system, Janko Kos spends his time largely on the problem of Metastasis, intersecting his research to questions surrounding Cancer stem cell. The concepts of his Cathepsin study are interwoven with issues in Immunohistochemistry, Angiogenesis, Cystatin and Stem cell, Cell biology.
In his work, Cytotoxic T cell is strongly intertwined with Cathepsin C, which is a subfield of Cystatin. Janko Kos has researched Stem cell in several fields, including Stromal cell, Cancer cell, Downregulation and upregulation, Molecular biology and Cathepsin B. His Biochemistry study which covers Cell culture that intersects with Cytotoxicity.
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The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases.
W. Bode;R. Engh;D. Musil;U. Thiele.
The EMBO Journal (1988)
Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody.
Petra Kocbek;Nataša Obermajer;Mateja Cegnar;Janko Kos.
Journal of Controlled Release (2007)
Cysteine proteinases and their endogenous inhibitors: target proteins for prognosis, diagnosis and therapy in cancer (review).
J Kos;T T Lah.
Oncology Reports (1998)
Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer.
Vito Turk;Boris Turk;Gregor Gunčar;Dušan Turk.
Advances in Enzyme Regulation (2002)
Cysteine Proteinase Inhibitors Stefin A, Stefin B, and Cystatin C in Sera from Patients with Colorectal Cancer: Relation to Prognosis
Janko Kos;Marta Krašovec;Nina Cimerman;Hans Jørgen Nielsen.
Clinical Cancer Research (2000)
Cathepsins B, H, and L and their inhibitors stefin A and cystatin C in sera of melanoma patients.
J Kos;B Stabuc;A Schweiger;M Krasovec.
Clinical Cancer Research (1997)
Serum cystatin C, a potent inhibitor of cysteine proteinases, is elevated in asthmatic patients.
Nina Cimerman;Pika Meško Brguljan;Marta Krašovec;Stanislav Šuškovič.
Clinica Chimica Acta (2000)
Cysteine proteinases and their inhibitors in extracellular fluids: markers for diagnosis and prognosis in cancer.
J Kos;B Werle;T Lah;N Brunner.
International Journal of Biological Markers (2000)
Mechanism of inhibition of papain by chicken egg white cystatin. Inhibition constants of N-terminally truncated forms and cyanogen bromide fragments of the inhibitor.
Werner Machleidt;Werner Machleidt;Ulrich Thiele;Ulrich Thiele;Bernd Laber;Bernd Laber;Irmgard Assfalg-Machleidt;Irmgard Assfalg-Machleidt.
FEBS Letters (1989)
Serum Cystatin C, a New Marker of Glomerular Filtration Rate, Is Increased during Malignant Progression
Janko Kos;Borut S̆tabuc;Nina Cimerman;Nils Brünner.
Clinical Chemistry (1998)
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