What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Cathepsin, Cathepsin B, Molecular biology, Biochemistry and Cystatin.
Janko Kos interconnects Cancer, Cancer research, Endogeny and Cell biology in the investigation of issues within Cathepsin.
His Cathepsin B study integrates concerns from other disciplines, such as Cathepsin L and Pathology.
His Molecular biology research integrates issues from Cell culture, Cathepsin O, Cathepsin H, Cathepsin D and Apoptosis.
His Biochemistry research focuses on Stereochemistry and how it connects with Recombinant DNA, Protein secondary structure, Turn and Mutant.
His study in Cystatin is interdisciplinary in nature, drawing from both Proteases, Cysteine, Enzyme inhibitor and PLGA.
His most cited work include:
- The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases. (498 citations)
- Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody. (326 citations)
- Cysteine proteinases and their endogenous inhibitors: target proteins for prognosis, diagnosis and therapy in cancer (review). (252 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Cathepsin, Molecular biology, Biochemistry, Cathepsin B and Cell biology.
He studies Cathepsin, namely Cathepsin S.
His studies in Molecular biology integrate themes in fields like Cathepsin D, Cystatin A, Gene and Antibody, Monoclonal antibody.
His work deals with themes such as Cathepsin L and Pathology, which intersect with Cathepsin B.
His Cell biology research incorporates elements of Cytotoxic T cell, Integrin, Immune system and Jurkat cells.
His biological study spans a wide range of topics, including Cancer and Metastasis.
He most often published in these fields:
- Cathepsin (38.33%)
- Molecular biology (35.00%)
- Biochemistry (30.33%)
What were the highlights of his more recent work (between 2017-2021)?
- Cathepsin (38.33%)
- Biochemistry (30.33%)
- Cancer research (14.33%)
In recent papers he was focusing on the following fields of study:
Janko Kos mainly investigates Cathepsin, Biochemistry, Cancer research, Cytotoxicity and Butyrylcholinesterase.
His Cathepsin study incorporates themes from Cystatin, Molecular biology, Perforin, Granzyme and Stem cell.
His Biochemistry research is multidisciplinary, incorporating perspectives in Chelation and Cell culture.
The various areas that he examines in his Cancer research study include Subventricular zone, Cell, Cellular localization and Immune system.
His research integrates issues of Cancer stem cell, Cancer and Metastasis in his study of Immune system.
Janko Kos regularly links together related areas like Nitroxoline in his Cathepsin B studies.
Between 2017 and 2021, his most popular works were:
- The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity (54 citations)
- Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities. (35 citations)
- Cysteine Cathepsins in Tumor-Associated Immune Cells. (30 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in Immune system, Butyrylcholinesterase, Cathepsin, Cancer and Cancer research.
While the research belongs to areas of Immune system, Janko Kos spends his time largely on the problem of Metastasis, intersecting his research to questions surrounding Cancer stem cell.
The concepts of his Cathepsin study are interwoven with issues in Immunohistochemistry, Angiogenesis, Cystatin and Stem cell, Cell biology.
In his work, Cytotoxic T cell is strongly intertwined with Cathepsin C, which is a subfield of Cystatin.
Janko Kos has researched Stem cell in several fields, including Stromal cell, Cancer cell, Downregulation and upregulation, Molecular biology and Cathepsin B.
His Biochemistry study which covers Cell culture that intersects with Cytotoxicity.
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