Janko Kos

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Slovenia Leader Award
• 2025 - Research.com Biology and Biochemistry in Slovenia Leader Award
• 2023 - Research.com Biology and Biochemistry in Slovenia Leader Award
• 2022 - Research.com Biology and Biochemistry in Slovenia Leader Award
• Member of the European Academy of Sciences and Arts
• Member of the European Academy of Sciences and Arts
• Member of the European Academy of Sciences and Arts

Overview

Best Publications

• The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases.

  W. Bode;R. Engh;D. Musil;U. Thiele

  836
  Citations

• Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody.

  Petra Kocbek;Nataša Obermajer;Mateja Cegnar;Janko Kos

  564
  Citations

• Cysteine proteinases and their endogenous inhibitors: target proteins for prognosis, diagnosis and therapy in cancer (review).

  J Kos;T T Lah

  383
  Citations

• Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor.

  Boris Brus;Urban Košak;Samo Turk;Anja Pišlar

  291
  Citations

• Cysteine Proteinase Inhibitors Stefin A, Stefin B, and Cystatin C in Sera from Patients with Colorectal Cancer: Relation to Prognosis

  Janko Kos;Marta Krašovec;Nina Cimerman;Hans Jørgen Nielsen

  274
  Citations

• Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer.

  Vito Turk;Boris Turk;Gregor Gunčar;Dušan Turk

  268
  Citations

• Cathepsins B, H, and L and their inhibitors stefin A and cystatin C in sera of melanoma patients.

  J Kos;B Stabuc;A Schweiger;M Krasovec

  260
  Citations

• Serum cystatin C, a potent inhibitor of cysteine proteinases, is elevated in asthmatic patients.

  Nina Cimerman;Pika Meško Brguljan;Marta Krašovec;Stanislav Šuškovič

  256
  Citations

• Cysteine proteinases and their inhibitors in extracellular fluids: markers for diagnosis and prognosis in cancer.

  J Kos;B Werle;T Lah;N Brunner

  235
  Citations

• Cystatins in Immune System

  Špela Magister;Janko Kos

  232
  Citations

• Mechanism of inhibition of papain by chicken egg white cystatin. Inhibition constants of N-terminally truncated forms and cyanogen bromide fragments of the inhibitor.

  Werner Machleidt;Werner Machleidt;Ulrich Thiele;Ulrich Thiele;Bernd Laber;Bernd Laber;Irmgard Assfalg-Machleidt;Irmgard Assfalg-Machleidt

  222
  Citations

• Serum Cystatin C, a New Marker of Glomerular Filtration Rate, Is Increased during Malignant Progression

  Janko Kos;Borut S̆tabuc;Nina Cimerman;Nils Brünner

  212
  Citations

• Proteins of higher fungi – from forest to application

  Jana Erjavec;Janko Kos;Maja Ravnikar;Tanja Dreo

  204
  Citations

• Cysteine cathepsins (proteases)—On the main stage of cancer?

  Vito Turk;Janko Kos;Boris Turk

  197
  Citations

• Microbial and fungal protease inhibitors—current and potential applications

  Jerica Sabotič;Janko Kos

  190
  Citations

• Prognostic significance of cathepsins B and L in primary human breast cancer.

  J. A. Foekens;J. Kos;H. A. Peters;M. Krasovec

  181
  Citations

• Intracellular and extracellular cathepsin B facilitate invasion of MCF-10A neoT cells through reconstituted extracellular matrix in vitro.

  Aleš Premzl;Valentina Zavašnik-Bergant;Vito Turk;Janko Kos

  181
  Citations

• Cysteine proteinases in cancer progression and their clinical relevance for prognosis.

  T T Lah;J Kos

  173
  Citations

• Regulation of the activity of lysosomal cysteine proteinases by pH-induced inactivation and/or endogenous protein inhibitors, cystatins.

  Boris Turk;Joseph G. Bieth;Ingemar Björk;Iztok Dolenc

  166
  Citations

• Cathepsin B immunohistochemical staining in tumor and endothelial cells is a new prognostic factor for survival in patients with brain tumors.

  Strojnik T;Kos J;Zidanik B;Golouh R

  164
  Citations