Ingemar Björk

Overview

Best Publications

• Role of the antithrombin-binding pentasaccharide in heparin acceleration of antithrombin-proteinase reactions. Resolution of the antithrombin conformational change contribution to heparin rate enhancement.

  S.T. Olson;I Björk;R Sheffer;P.A. Craig

  666
  Citations

• Mechanism of the anticoagulant action of heparin

  I. Björk;U. Lindahl

  661
  Citations

• Anticoagulant activity of heparin: Separation of high-activity and low-activity heparin species by affinity chromatography on immobilized antithrombin

  Magnus Höök;Ingemar Björk;John Hopwood;Ulf Lindahl

  539
  Citations

• Extension and structural variability of the antithrombin-binding sequence in heparin.

  Ulf Lindahl;Lennart Thunberg;Gudrun Backstrom;Johan Riesenfeld

  463
  Citations

• Kinetic characterization of heparin-catalyzed and uncatalyzed inhibition of blood coagulation proteinases by antithrombin

  Steven T. Olson;Ingemar Björk;Joseph D. Shore

  365
  Citations

• Role of ternary complexes, in which heparin binds both antithrombin and proteinase, in the acceleration of the reactions between antithrombin and thrombin or factor Xa.

  A Danielsson;E Raub;U Lindahl;I Björk

  332
  Citations

• Binding of high affinity heparin to antithrombin III. Stopped flow kinetic studies of the binding interaction.

  S.T. Olson;K.R. Srinivasan;I. Björk;J.D. Shore

  316
  Citations

• Mechanism of Heparin Activation of Antithrombin ROLE OF INDIVIDUAL RESIDUES OF THE PENTASACCHARIDE ACTIVATING SEQUENCE IN THE RECOGNITION OF NATIVE AND ACTIVATED STATES OF ANTITHROMBIN

  Umesh R. Desai;Maurice Petitou;Ingemar Björk;Steven T. Olson

  275
  Citations

• Quantitative characterization of the thrombin-heparin interaction. Discrimination between specific and nonspecific binding models.

  Unknown

  218
  Citations

• Predominant contribution of surface approximation to the mechanism of heparin acceleration of the antithrombin-thrombin reaction. Elucidation from salt concentration effects.

  Unknown

  209
  Citations

• Some Physicochemical Properties of Protein A from Staphylococcus aureus

  Unknown

  204
  Citations

• The size and shape of human and bovine antithrombin III.

  Unknown

  190
  Citations

• The binding of low-affinity and high-affinity heparin to antithrombin. Fluorescence studies.

  Birgitta Nordenman;Åke Danielsson;Ingemar Björk

  188
  Citations

• Regulation of Thrombin Activity by Antithrombin and Heparin

  Steven T. Olson;Ingemar Björk

  186
  Citations

• Binding of low-affinity and high-affinity heparin to antithrombin. Ultraviolet difference spectroscopy and circular dichroism studies.

  Birgitta Nordenman;Ingemar Bjork

  180
  Citations

• Accelerating ability of synthetic oligosaccharides on antithrombin inhibition of proteinases of the clotting and fibrinolytic systems Comparison with heparin and low-molecular-weight heparin

  Steven T. Olson;Richard Swanson;Elke Raub-Segall;Tina Bedsted

  177
  Citations

• The active site of antithrombin. Release of the same proteolytically cleaved form of the inhibitor from complexes with factor IXa, factor Xa, and thrombin.

  I Björk;C M Jackson;H Jörnvall;K K Lavine

  174
  Citations

• Regulation of the activity of lysosomal cysteine proteinases by pH-induced inactivation and/or endogenous protein inhibitors, cystatins.

  Boris Turk;Joseph G. Bieth;Ingemar Björk;Iztok Dolenc

  166
  Citations

• Evidence for similar conformational changes in α2-macroglobulin on reaction with primary amines or proteolytic enzymes

  Ingemar Björk;Wayne W. Fish

  162
  Citations

• Reinvestigation of some physicochemical and chemical properties of human ceruloplasmin (ferroxidase).

  Lars Ryden;Ingemar Bjork

  161
  Citations

• Conversion of antithrombin from an inhibitor of thrombin to a substrate with reduced heparin affinity and enhanced conformational stability by binding of a tetradecapeptide corresponding to the P1 to P14 region of the putative reactive bond loop of the inhibitor.

  I Björk;K Ylinenjärvi;S T Olson;P E Bock

  161
  Citations

• Heparin and related polysaccharides

  D. A. Lane;Ingemar Björk;Ulf Lindahl

  154
  Citations

• A fragment of histidine-rich glycoprotein is a potent inhibitor of tumor vascularization.

  Anna-Karin Olsson;Helena Larsson;Johan Dixelius;Irja Johansson

  146
  Citations

• Structure and Antithrombin-Binding Properties of Heparin Isolated From the Clams Anomalocardia Brasiliana and Tivela Mactroides

  Gunnar Pejler;Ake Danielsson;Ingemar Bjork;Ulf Lindahl

  137
  Citations