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Jan M. Deussing

Jan M. Deussing

D-Index & Metrics

Neuroscience

D-Index
66
Citations
17215
World Ranking
2993
National Ranking
259

Overview

Jan M. Deussing is affiliated with the Max Planck Society in Germany. Their research spans multiple disciplines with a focus primarily on neuroscience, biochemistry, genetics, molecular biology, and medicine.

The scientist's main fields of study include:

  • Neuroscience
  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their work extends into specialized subfields such as behavioral neuroscience, physiology, biological psychiatry, molecular biology, and social psychology.

  • Behavioral Neuroscience
  • Physiology
  • Biological Psychiatry
  • Molecular Biology
  • Social Psychology

The principal topics addressed in Jan M. Deussing's research encompass diverse biological systems and mechanisms, including:

  • Stress Responses and Cortisol
  • Tryptophan and brain disorders
  • Neuroendocrine regulation and behavior
  • Adenosine and Purinergic Signaling
  • Adipose Tissue and Metabolism
  • Circadian rhythm and melatonin
  • Hormonal Regulation and Hypertension

Selected recent papers by Jan M. Deussing include:

  • "The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice", 2021, Molecular Psychiatry
  • "Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2", 2022, Neuron
  • "Introducing a depression-like syndrome for translational neuropsychiatry: a plea for taxonomical validity and improved comparability between humans and mice", 2022, Molecular Psychiatry
  • "Opposite effects of stress on effortful motivation in high and low anxiety are mediated by CRHR1 in the VTA", 2022, Science Advances
  • "P2X7R antagonists in chronic stress-based depression models: a review", 2021, European Archives of Psychiatry and Clinical Neuroscience

Jan M. Deussing has published extensively in several venues across the fields they study. The most frequent publication venues are:

  • Molecular Psychiatry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science Advances
  • European Archives of Psychiatry and Clinical Neuroscience
  • Cell Reports

The scientist collaborates regularly with several researchers, including:

  • Mathias V. Schmidt
  • Joeri Bordes
  • Lea M. Brix
  • Alon Chen
  • Lotte van Doeselaar

Best Publications

  • Ultramicroscopy: three-dimensional visualization of neuronal networks in the whole mouse brain.

    Hans-Ulrich Dodt;Ulrich Leischner;Anja Schierloh;Nina Jährling;Nina Jährling

  • Cathepsin B contributes to TNF-α–mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

    M. Eugenia Guicciardi;Jan Deussing;Hideyuki Miyoshi;Steven F. Bronk

  • Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus.

    Terry Nakagawa;Wera Roth;Phillip Wong;Andrew Nelson

  • Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

    Walter Halangk;Markus M. Lerch;Barbara Brandt-Nedelev;Wera Roth

  • Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress.

    Marianne B Müller;Stephan Zimmermann;Inge Sillaber;Thomas P Hagemeyer

  • Tumor Cell–Derived and Macrophage-Derived Cathepsin B Promotes Progression and Lung Metastasis of Mammary Cancer

    Olga Vasiljeva;Anna Papazoglou;Achim Krüger;Harald Brodoefel

  • Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling

    Wera Roth;Wera Roth;Jan Deussing;Vladimir A. Botchkarev;Meike Pauly-Evers;Meike Pauly-Evers

  • The Role of m6A/m-RNA Methylation in Stress Response Regulation

    Mareen Engel;Carola Eggert;Paul M. Kaplick;Matthias Eder

  • Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells.

    Daniel H. Ebert;Jan Deussing;Christoph Peters;Terence S. Dermody

  • Identification of Glyoxalase-I as a Protein Marker in a Mouse Model of Extremes in Trait Anxiety

    Simone A. Krömer;Melanie S. Keßler;Dale Milfay;Isabel N. Birg

  • Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1

    Damian Refojo;Martin Schweizer;Claudia Kuehne;Stefanie Ehrenberg

  • Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation

    Jan Deussing;Wera Roth;Paul Saftig;Christoph Peters

  • Proteases involved in MHC class II antigen presentation.

    Jose A. Villadangos;Rebecca A. R. Bryant;Jan Deussing;Christoph Driessen

  • Thyroid functions of mouse cathepsins B, K, and L

    Bianca Friedrichs;Carmen Tepel;Thomas Reinheckel;Jan Deussing

  • The Corticotropin-Releasing Factor Family: Physiology of the Stress Response.

    Jan M. Deussing;Alon Chen

  • Region-specific roles of the corticotropin-releasing factor-urocortin system in stress

    Marloes J. A. G. Henckens;Jan M. Deussing;Alon Chen

  • Corticotropin-Releasing Hormone Drives Anandamide Hydrolysis in the Amygdala to Promote Anxiety

    J. Megan Gray;Haley A. Vecchiarelli;Maria Morena;Tiffany T. Y. Lee

  • Towards specific functions of lysosomal cysteine peptidases: phenotypes of mice deficient for cathepsin B or cathepsin L.

    Thomas Reinheckel;Jan Deussing;Wera Roth;Christoph Peters

  • Animal models of depression

    Jan M. Deussing

  • Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients.

    Andreas Menke;Janine Arloth;Benno Pütz;Peter Weber

  • Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices

    Gerhard Rammes;Anne Hasenjäger;Kamila Sroka-Saidi;Jan M. Deussing

  • TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies.

    A. Erhardt;L. Czibere;D. Roeske;S. Lucae

  • Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice

    Lisa Sevenich;Uta Schurigt;Kathrin Sachse;Mieczyslaw Gajda

  • Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans

    Nils C. Gassen;Jakob Hartmann;Jürgen Zschocke;Jens Stepan

  • Forebrain CRF₁ modulates early-life stress-programmed cognitive deficits.

    Xiao-Dong Wang;Gerhard Rammes;Igor Kraev;Miriam Wolf

Frequent Co-Authors

Alon Chen
Alon Chen Weizmann Institute of Science
Carsten T. Wotjak
Carsten T. Wotjak Max Planck Society
Matthias Eder
Matthias Eder Max Planck Society
Marianne B. Müller
Marianne B. Müller Johannes Gutenberg University of Mainz
Elisabeth B. Binder
Elisabeth B. Binder Max Planck Society
Gerhard Rammes
Gerhard Rammes Technical University of Munich
Kerry J. Ressler
Kerry J. Ressler Harvard University
Günter K. Stalla
Günter K. Stalla Ludwig-Maximilians-Universität München
Bertram Müller-Myhsok
Bertram Müller-Myhsok Max Planck Society
Nicolas Singewald
Nicolas Singewald University of Innsbruck

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