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Neuroscience

D-Index
54
Citations
13884
World Ranking
4863
National Ranking
405

Overview

Thomas Misgeld is affiliated with the Technical University of Munich in Germany. Their research output encompasses a broad range of topics predominantly situated within the fields of Biochemistry, Genetics and Molecular Biology, as well as Neuroscience.

Their scientific work includes contributions to several subfields such as Molecular Biology, Neurology, Cellular and Molecular Neuroscience, Developmental Neuroscience, and Cell Biology. These areas reflect a deep engagement with the molecular and cellular mechanisms underlying neurological functions and disorders.

Key topics of their research focus on:

  • Neurogenesis and neuroplasticity mechanisms
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Advanced Electron Microscopy Techniques and Applications
  • Axon Guidance and Neuronal Signaling
  • Microtubule and mitosis dynamics
  • Multiple Sclerosis Research Studies
  • Mitochondrial Function and Pathology

Misgeld has been published extensively in scientific venues, with frequent contributions to bioRxiv (Cold Spring Harbor Laboratory) where 13 publications are recorded. Other notable venues include Nature Immunology, eLife, Nature Communications, and Neuron, indicating active participation in high-impact journals related to immunology and neuroscience.

Their recent papers include:

  • Novel Hexb-based tools for studying microglia in the CNS, 2020, Nature Immunology
  • Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal, 2020, Nature Immunology
  • Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation, 2021, Nature Neuroscience
  • Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease, 2023, Science
  • Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS, 2020, Acta Neuropathologica

Misgeld's work has also involved collaboration with multiple coauthors frequently contributing alongside them. These coauthors include Martina Schifferer, Martin Kerschensteiner, Monika S. Brill, Georg Kislinger, and Nicolas Snaidero, who have appeared in significant numbers of joint publications.

Best Publications

  • Activated Human T Cells, B Cells, and Monocytes Produce Brain-derived Neurotrophic Factor In Vitro and in Inflammatory Brain Lesions: A Neuroprotective Role of Inflammation?

    Martin Kerschensteiner;Eike Gallmeier;Lüder Behrens;Vivian Vargas Leal

  • A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

    Ivana Nikić;Doron Merkler;Doron Merkler;Catherine Sorbara;Mary Brinkoetter

  • In vivo imaging of axonal degeneration and regeneration in the injured spinal cord.

    Martin Kerschensteiner;Martin E Schwab;Jeff W Lichtman;Thomas Misgeld

  • Mitostasis in Neurons: Maintaining Mitochondria in an Extended Cellular Architecture

    Thomas Misgeld;Thomas L. Schwarz;Thomas L. Schwarz

  • BDNF and gp145trkB in multiple sclerosis brain lesions: neuroprotective interactions between immune and neuronal cells?

    Christine Stadelmann;Martin Kerschensteiner;Thomas Misgeld;Wolfgang Brück

  • Imaging axonal transport of mitochondria in vivo.

    Thomas Misgeld;Thomas Misgeld;Martin Kerschensteiner;Martin Kerschensteiner;Florence M Bareyre;Florence M Bareyre;Robert W Burgess

  • Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic T H 17 cells

    Sylvia Heink;Nir Yogev;Christoph Garbers;Marina Herwerth

  • Roles of neurotransmitter in synapse formation: development of neuromuscular junctions lacking choline acetyltransferase.

    Thomas Misgeld;Robert W Burgess;Renate M Lewis;Jeanette M Cunningham

  • Neurotrophins inhibit major histocompatibility class II inducibility of microglia: Involvement of the p75 neurotrophin receptor

    Harald Neumann;Thomas Misgeld;Kenji Matsumuro;Hartmut Wekerle

  • TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.

    Fargol Mazaheri;Nicolas Snaidero;Nicolas Snaidero;Gernot Kleinberger;Charlotte Madore

  • Assembly of the postsynaptic membrane at the neuromuscular junction: paradigm lost

    Terrance T Kummer;Thomas Misgeld;Joshua R Sanes

  • Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity

    Caroline Fecher;Caroline Fecher;Caroline Fecher;Laura Trovò;Laura Trovò;Stephan A. Müller;Stephan A. Müller;Nicolas Snaidero;Nicolas Snaidero

  • Axon branch removal at developing synapses by axosome shedding.

    Derron L. Bishop;Thomas Misgeld;Thomas Misgeld;Mark K. Walsh;Wen-Biao Gan

  • Novel Hexb-based tools for studying microglia in the CNS.

    Takahiro Masuda;Takahiro Masuda;Lukas Amann;Roman Sankowski;Ori Staszewski

  • In vivo imaging reveals a phase-specific role of STAT3 during central and peripheral nervous system axon regeneration.

    Florence M. Bareyre;Natalie Garzorz;Claudia Lang;Thomas Misgeld

  • Transgenic labeling of the corticospinal tract for monitoring axonal responses to spinal cord injury

    Florence M Bareyre;Martin Kerschensteiner;Thomas Misgeld;Joshua R Sanes

  • In vivo imaging of the diseased nervous system

    Thomas Misgeld;Martin Kerschensteiner;Martin Kerschensteiner

  • Agrin promotes synaptic differentiation by counteracting an inhibitory effect of neurotransmitter.

    Thomas Misgeld;Terrance T. Kummer;Jeff W. Lichtman;Joshua R. Sanes

  • Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies

    Robert Adalbert;Antal Nogradi;Elisabetta Babetto;Lucie Janeckova

  • Multiparametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo

    Michael O Breckwoldt;Franz M J Pfister;Peter M Bradley;Petar Marinković

  • Nerve-independent formation of a topologically complex postsynaptic apparatus

    Terrance T. Kummer;Thomas Misgeld;Jeff W. Lichtman;Joshua R. Sanes

  • Effects of neurotoxic and neuroprotective agents on peripheral nerve regeneration assayed by time-lapse imaging in vivo

    Y. Albert Pan;Thomas Misgeld;Jeff W. Lichtman;Joshua R. Sanes

Frequent Co-Authors

Jeff W. Lichtman
Jeff W. Lichtman Harvard University
Joshua R. Sanes
Joshua R. Sanes Harvard University
Arthur Konnerth
Arthur Konnerth Technical University of Munich
Christian Haass
Christian Haass Ludwig-Maximilians-Universität München
Martin E. Schwab
Martin E. Schwab University of Zurich
Fred Wolf
Fred Wolf Max Planck Society
Andreas Vlachos
Andreas Vlachos University of Freiburg
Binhai Zheng
Binhai Zheng University of California, San Diego
Robert W. Burgess
Robert W. Burgess The Jackson Laboratory
Karl-Klaus Conzelmann
Karl-Klaus Conzelmann Ludwig-Maximilians-Universität München

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