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D-Index & Metrics

Molecular Biology

D-Index
59
Citations
13311
World Ranking
2016
National Ranking
1002

Overview

Sergei Y. Sokol is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with specific emphasis on Molecular Biology, Cell Biology, Genetics, Cellular and Molecular Neuroscience, and Ecology.

Their academic focus explores a variety of topics, including:

  • Developmental Biology and Gene Regulation
  • Wnt/β-catenin signaling in development and cancer
  • Cellular Mechanics and Interactions
  • Hippo pathway signaling and YAP/TAZ
  • Renal and related cancers
  • Fibroblast Growth Factor Research
  • Microtubule and mitosis dynamics

Sergei Y. Sokol has published extensively, with research appearing frequently in several venues. The most common publication outlets include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Development
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Nature Communications
  • Biology Open

Recent papers authored or co-authored by Sergei Y. Sokol feature the following titles, years of publication, and venues:

  • Planar cell polarity pathway in kidney development, function and disease, 2021, Nature Reviews Nephrology
  • Lmo7 recruits myosin II heavy chain to regulate actomyosin contractility and apical domain size in Xenopus ectoderm, 2022, Development
  • Rspo2 antagonizes FGF signaling during vertebrate mesoderm formation and patterning, 2020, Development
  • Mechanical control of neural plate folding by apical domain alteration, 2023, Nature Communications
  • The dorsal blastopore lip is a source of signals inducing planar cell polarity in the Xenopus neural plate, 2021, Biology Open

Collaboration is a significant aspect of their research efforts. Frequent co-authors include:

  • Keiji Itoh
  • Olga Ossipova
  • Miho Matsuda
  • Chih-Wen Chu
  • Alice H. Reis

Sergei Y. Sokol's contributions to molecular and developmental biology reflect a broad engagement with the mechanisms underlying cellular processes and developmental signaling pathways. Their work addresses several complex biological systems ranging from kidney development to neural plate dynamics and mesoderm patterning.

Best Publications

  • Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

    Mikhail V Semënov;Keiko Tamai;Barbara K Brott;Michael Kühl

  • Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures.

    G. Thomsen;T. Woolf;M. Whitman;S. Sokol

  • Functional and structural diversity of the human Dickkopf gene family.

    Valery E. Krupnik;John D. Sharp;Chian Jiang;Keith Robison

  • Injected Wnt RNA induces a complete body axis in Xenopus embryos.

    Sergei Sokol;Jan L. Christian;Randall T. Moon;Douglas A. Melton

  • Analysis of Dishevelled signalling pathways during Xenopus development

    Sergei Y. Sokol

  • A two-step model for the localization of maternal mRNA in Xenopus oocytes: involvement of microtubules and microfilaments in the translocation and anchoring of Vg1 mRNA

    J.K. Yisraeli;S. Sokol;D.A. Melton

  • The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early xenopus development

    Terry L Tang;Robert M Freeman;Alana M O'Reilly;Benjamin G Neel

  • Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos

    Isabel Dominguez;Keiji Itoh;Sergei Y. Sokol

  • Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and β-catenin

    Keiji Itoh;Valery E. Krupnik;Sergei Y. Sokol

  • Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.

    Barbara K. Brott;Sergei Y. Sokol;Sergei Y. Sokol

  • Maintaining embryonic stem cell pluripotency with Wnt signaling

    Sergei Y. Sokol

  • The Polycystic Kidney Disease 1 Gene Product Modulates Wnt Signaling

    Emily Kim;Thierry Arnould;Lorenz K. Sellin;Thomas Benzing

  • Nuclear localization is required for Dishevelled function in Wnt/β-catenin signaling

    Keiji Itoh;Barbara K Brott;Gyu-Un Bae;Marianne J Ratcliffe

  • Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled.

    Sergei Y. Sokol;John Klingensmith;Norbert Perrimon;Keiji Itoh

  • PRE-EXISTENT PATTERN IN XENOPUS ANIMAL POLE CELLS REVEALED BY INDUCTION WITH ACTIVIN

    S. Sokol;D. A. Melton

  • Axis determination by inhibition of Wnt signaling in Xenopus

    Keiji Itoh;Sergei Y. Sokol

  • Wnt Signaling in Vertebrate Axis Specification

    Hiroki Hikasa;Sergei Y. Sokol

  • Endostatin is a potential inhibitor of Wnt signaling

    Jun-ichi Hanai;Joachim Gloy;Joachim Gloy;S. Ananth Karumanchi;Sujata Kale

  • Wnt3a-Mediated Formation of Phosphatidylinositol 4,5-Bisphosphate Regulates LRP6 Phosphorylation

    Weijun Pan;Sun-Cheol Choi;He Wang;Yuanbo Qin

  • A mouse macrophage factor induces head structures and organizes a body axis in Xenopus

    S Sokol;GG Wong;DA Melton

Frequent Co-Authors

Douglas A. Melton
Douglas A. Melton Harvard University
Pierre D. McCrea
Pierre D. McCrea The University of Texas MD Anderson Cancer Center
Lei Li
Lei Li The University of Texas MD Anderson Cancer Center
Xi He
Xi He Boston Children's Hospital
Randall T. Moon
Randall T. Moon University of Washington
Marek Mlodzik
Marek Mlodzik Icahn School of Medicine at Mount Sinai
Benjamin G. Neel
Benjamin G. Neel New York University Langone Medical Center
Gerd Walz
Gerd Walz University of Freiburg
Patricia A. D'Amore
Patricia A. D'Amore Massachusetts Eye and Ear Infirmary
Norbert Perrimon
Norbert Perrimon Harvard University

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