Elena I. Deryugina

Overview

Best Publications

• Matrix metalloproteinases and tumor metastasis

  Elena I. Deryugina;James P. Quigley

  2732
  Citations

• Compensation mechanism in tumor cell migration: mesenchymal–amoeboid transition after blocking of pericellular proteolysis

  Katarina Wolf;Irina Mazo;Harry Leung;Katharina Engelke

  1809
  Citations

• Collagen-based cell migration models in vitro and in vivo

  Katarina Wolf;Stephanie Alexander;Vivien Schacht;Lisa M. Coussens

  812
  Citations

• Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis.

  Veronica C. Ardi;Tatyana A. Kupriyanova;Elena I. Deryugina;James P. Quigley

  693
  Citations

• MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells.

  Elena I. Deryugina;Boris Ratnikov;Edward Monosov;Tanya I. Postnova

  517
  Citations

• Tumor angiogenesis: MMP-mediated induction of intravasation- and metastasis-sustaining neovasculature.

  Elena I. Deryugina;James P. Quigley

  463
  Citations

• Tumor-Recruited Neutrophils and Neutrophil TIMP-Free MMP-9 Regulate Coordinately the Levels of Tumor Angiogenesis and Efficiency of Malignant Cell Intravasation

  Erin M. Bekes;Bernhard Schweighofer;Tatyana A. Kupriyanova;Ewa Zajac

  369
  Citations

• Chick embryo chorioallantoic membrane model systems to study and visualize human tumor cell metastasis.

  Elena I. Deryugina;James P. Quigley

  321
  Citations

• Tissue-infiltrating neutrophils constitute the major in vivo source of angiogenesis-inducing MMP-9 in the tumor microenvironment.

  Elena I. Deryugina;Ewa Zajac;Anna Juncker-Jensen;Tatyana A. Kupriyanova

  320
  Citations

• Matrix-dependent Proteolysis of Surface Transglutaminase by Membrane-type Metalloproteinase Regulates Cancer Cell Adhesion and Locomotion

  Alexey M. Belkin;Sergey S. Akimov;Liubov S. Zaritskaya;Boris I. Ratnikov

  310
  Citations

• Processing of Integrin αv Subunit by Membrane Type 1 Matrix Metalloproteinase Stimulates Migration of Breast Carcinoma Cells on Vitronectin and Enhances Tyrosine Phosphorylation of Focal Adhesion Kinase

  Elena I. Deryugina;Boris I. Ratnikov;Tanya I. Postnova;Dmitri V. Rozanov

  305
  Citations

• Pleiotropic Roles of Matrix Metalloproteinases in Tumor Angiogenesis: Contrasting, Overlapping and Compensatory Functions

  Elena I. Deryugina;James P. Quigley

  297
  Citations

• Angiogenic capacity of M1- and M2-polarized macrophages is determined by the levels of TIMP-1 complexed with their secreted proMMP-9

  Ewa Zajac;Bernhard Schweighofer;Tatyana A. Kupriyanova;Anna Juncker-Jensen

  279
  Citations

• Stromal cells in long-term cultures: keys to the elucidation of hematopoietic development?

  Deryugina Ei;Müller-Sieburg Ce

  243
  Citations

• Remodeling of Collagen Matrix by Human Tumor Cells Requires Activation and Cell Surface Association of Matrix Metalloproteinase-2

  Elena I. Deryugina;Mario A. Bourdon;Ralph A. Reisfeld;Alex Strongin

  242
  Citations

• Mutation Analysis of Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) THE ROLE OF THE CYTOPLASMIC TAIL CYS574, THE ACTIVE SITE GLU240, AND FURIN CLEAVAGE MOTIFS IN OLIGOMERIZATION, PROCESSING, AND SELF-PROTEOLYSIS OF MT1-MMP EXPRESSED IN BREAST CARCINOMA CELLS

  Dmitry V. Rozanov;Elena I. Deryugina;Boris I. Ratnikov;Edward Z. Monosov

  230
  Citations

• Functional activation of integrin alpha V beta 3 in tumor cells expressing membrane-type 1 matrix metalloproteinase.

  Elena I. Deryugina;Mario A. Bourdon;Karli Jungwirth;Jeffrey W. Smith

  228
  Citations

• Up-Regulation of Vascular Endothelial Growth Factor by Membrane-type 1 Matrix Metalloproteinase Stimulates Human Glioma Xenograft Growth and Angiogenesis

  Elena I. Deryugina;Liliana Soroceanu;Alex Y. Strongin

  225
  Citations

• Cell surface remodeling by plasmin: a new function for an old enzyme.

  Elena I. Deryugina;James P. Quigley

  223
  Citations

• Matrix metalloproteinase-2 activation modulates glioma cell migration

  Elena I. Deryugina;Mario A. Bourdon;Guang-Xiang Luo;Ralph A. Reisfeld

  219
  Citations