Harold A. Chapman

Overview

Best Publications

• Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix

  Kevin K. Kim;Matthias C. Kugler;Paul J. Wolters;Liliane Robillard

  1469
  Citations

• Pycnodysostosis, a Lysosomal Disease Caused by Cathepsin K Deficiency

  Bruce D. Gelb;Guo-Ping Shi;Harold A. Chapman;Robert J. Desnick

  1456
  Citations

• EMERGING ROLES FOR CYSTEINE PROTEASES IN HUMAN BIOLOGY

  Harold A. Chapman;Richard J. Riese;Guo-Ping Shi

  1107
  Citations

• Regulation of Integrin Function by the Urokinase Receptor

  Ying Wei;Matvey Lukashev;Daniel I. Simon;Sarah C. Bodary

  1086
  Citations

• Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells.

  Galina K. Sukhova;Guo Ping Shi;Daniel I. Simon;Harold A. Chapman

  990
  Citations

• Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function.

  Brigid L.M. Hogan;Christina E. Barkauskas;Harold A. Chapman;Jonathan A. Epstein

  952
  Citations

• Identification of the urokinase receptor as an adhesion receptor for vitronectin.

  Ying Wei;D. A. Waltz;Navaneetha Rao;R. J. Drummond

  833
  Citations

• Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase– and cathepsin-dependent emphysema

  Tao Zheng;Zhou Zhu;Zhongde Wang;Robert J. Homer;Robert J. Homer

  828
  Citations

• The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

  Sarah E. Ewald;Bettina L. Lee;Laura Lau;Katherine E. Wickliffe

  729
  Citations

• Essential Role for Cathepsin S in MHC Class II–Associated Invariant Chain Processing and Peptide Loading

  Richard J Riese;Paula R Wolf;Dieter Brömme;Lisa R Natkin

  713
  Citations

• Plasminogen activators, integrins, and the coordinated regulation of cell adhesion and migration.

  Harold A Chapman

  683
  Citations

• Cathepsin S Required for Normal MHC Class II Peptide Loading and Germinal Center Development

  Guo-Ping Shi;Jose A Villadangos;Glenn Dranoff;Clayton Small

  682
  Citations

• Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury

  Andrew E. Vaughan;Alexis N. Brumwell;Ying Xi;Jeffrey E. Gotts

  665
  Citations

• Cystatin C deficiency in human atherosclerosis and aortic aneurysms.

  Guo-Ping Shi;Galina K. Sukhova;Anders Grubb;Anique Ducharme

  654
  Citations

• TGF-β1 Signaling and Tissue Fibrosis.

  Kevin K. Kim;Dean Sheppard;Harold A. Chapman

  594
  Citations

• A Role for Caveolin and the Urokinase Receptor in Integrin-mediated Adhesion and Signaling

  Ying Wei;Xiuwei Yang;Qiumei Liu;John A. Wilkins

  591
  Citations

• Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice

  Harold A. Chapman;Xiaopeng Li;Jonathan P. Alexander;Alexis Brumwell

  560
  Citations

• Interferon γ induction of pulmonary emphysema in the adult murine lung

  Zhongde Wang;Tao Zheng;Zhou Zhu;Robert J. Homer

  539
  Citations

• Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease: Risk to relatives for airflow obstruction and chronic bronchitis

  Edwin K. Silverman;Harold A. Chapman;Jeffrey M. Drazen;Scott T. Weiss

  499
  Citations

• Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis

  Maximilian Strunz;Lukas M. Simon;Meshal Ansari;Jaymin J. Kathiriya

  497
  Citations