John B. Hibbs

Overview

Best Publications

• Nitric oxide: a cytotoxic activated macrophage effector molecule.

  John B. Hibbs;Read R. Taintor;Zdenek Vavrin;Elliot M. Rachlin

  2847
  Citations

• Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite.

  John B. Hibbs;Read R. Taintor;Zdenek Vavrin

  2142
  Citations

• Role of nitric oxide synthesis in macrophage antimicrobial activity.

  Carl F. Nathan;John B. Hibbs;John B. Hibbs

  2113
  Citations

• L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.

  J B Hibbs;Z Vavrin;R R Taintor

  1308
  Citations

• Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism.

  Shawn J Green;Monte S Meltzer;John B Hibbs;Carol A Nacy

  883
  Citations

• EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages.

  J R Lancaster;J B Hibbs

  716
  Citations

• Interferon-γ and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages*

  Jean‐Claude Drapier;Juana Wietzerbin;John B. Hibbs

  673
  Citations

• Evidence for cytokine-inducible nitric oxide synthesis from L-arginine in patients receiving interleukin-2 therapy.

  J B Hibbs;C Westenfelder;R Taintor;Z Vavrin

  650
  Citations

• Measurement of nitrate and nitrite in biological samples using nitrate reductase and Griess reaction.

  Donald L. Granger;Read R. Taintor;Kenneth S. Boockvar;John B. Hibbs

  628
  Citations

• Possible role of macrophage mediated nonspecific cytotoxicity in tumour resistance.

  John B. Hibbs;Lewis H. Lambert;Jack S. Remington

  511
  Citations

• Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages.

  Donald L. Granger;John B. Hibbs;John R. Perfect;David T. Durack

  454
  Citations

• Macrophage tumor killing: influence of the local environment.

  JB Hibbs;RR Taintor;HA Chapman;JB Weinberg

  446
  Citations

• Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages.

  D L Granger;J B Hibbs;J R Perfect;D T Durack

  429
  Citations

• Characterization of the Effects of Endotoxin on Macrophage Tumor Cell Killing

  J. Brice Weinberg;Harold A. Chapman;John B. Hibbs

  368
  Citations

• Synthesis of nitric oxide from a terminal guanidino nitrogen atom of L-arginine: A molecular mechanism regulating cellular proliferation that targets intracellular iron

  J. B. Hibbs;R. R. Taintor;Z. Vavrin;D. L. Granger

  302
  Citations

• Macrophage fibrinolytic activity: identification of two pathways of plasmin formation by intact cells and of a plasminogen activator inhibitor

  Harold A. Chapman;Zdenik Vavrin;John B. Hibbs

  302
  Citations

• Control of Carcinogenesis: A Possible Role for the Activated Macrophage

  John B. Hibbs;Lewis H. Lambert;Jack S. Remington

  298
  Citations

• Injury of neoplastic cells by murine macrophages leads to inhibition of mitochondrial respiration

  D L Granger;R R Taintor;J L Cook;J B Hibbs

  265
  Citations

• Discrimination Between Neoplastic and Non-Neoplastic Cells In Vitro by Activated Macrophages

  John B. Hibbs

  257
  Citations

• Iron depletion: possible cause of tumor cell cytotoxicity induced by activated macrophages.

  John B. Hibbs;John B. Hibbs;Read R. Taintor;Read R. Taintor;Zdenek Vavrin;Zdenek Vavrin

  255
  Citations