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Microbiology

D-Index
42
Citations
10082
World Ranking
5319
National Ranking
2020

Overview

Janis J. Weis is affiliated with the University of Utah in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology. Within these broad areas, their work focuses on subfields such as Parasitology, Molecular Biology, Infectious Diseases, Immunology, and Rehabilitation.

The scientist's main research topics include Vector-borne infectious diseases, Viral Infections and Vectors, Exercise and Physiological Responses, Muscle Physiology and Disorders, interferon and immune responses, Dermatology and Skin Diseases, and Autoimmune and Inflammatory Disorders Research.

Recent publications authored or co-authored by Janis J. Weis include:

  • Lyme arthritis: linking infection, inflammation and autoimmunity (2021, Nature Reviews Rheumatology)
  • Association of Persistent Symptoms after Lyme Neuroborreliosis and Increased Levels of Interferon-α in Blood (2023, Emerging infectious diseases)
  • The Cdkn2a gene product p19 alternative reading frame (p19ARF) is a critical regulator of IFNβ-mediated Lyme arthritis (2022, PLoS Pathogens)
  • Genetic mechanisms contributing to IFNβ regulation of Lyme Arthritis: involvement of the Borrelia burgdorferi arthritis associated locus 1 (Bbaa1) (2020, The Journal of Immunology)
  • The Cdkn2a gene product p19ARF (alternative reading frame) is a critical regulator of IFNβ-mediated Lyme arthritis (2022, The Journal of Immunology)

Janis J. Weis has frequently published in journals such as The Journal of Immunology, Physiology, Nature Reviews Rheumatology, Emerging infectious diseases, and PLoS Pathogens.

Collaborations are an important aspect of their research, with frequent co-authors including Jinze Li, Ying Ma, Jackie K. Paquette, Cory Teuscher, and James F. Zachary.

Best Publications

  • Quantification of low-copy transcripts by continuous SYBR® Green I monitoring during amplification

    Tom B. Morrison;Janis J. Weis;Carl T. Wittwer

  • Cutting Edge: Repurification of Lipopolysaccharide Eliminates Signaling Through Both Human and Murine Toll-Like Receptor 2

    Matthew Hirschfeld;Ying Ma;John H. Weis;Stefanie N. Vogel

  • Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2.

    J D Fingeroth;J J Weis;T F Tedder;J L Strominger

  • Signaling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages.

    Matthew Hirschfeld;Janis J. Weis;Vladimir Toshchakov;Cindy A. Salkowski

  • Cutting Edge: Inflammatory Signaling by Borrelia burgdorferi Lipoproteins Is Mediated by Toll-Like Receptor 2

    M Hirschfeld;C J Kirschning;R Schwandner;H Wesche

  • Epstein-Barr Virus gp350/220 Binding to the B Lymphocyte C3d Receptor Mediates Adsorption, Capping, and Endocytosis

    Jerome Tanner;Janis Weis;Janis Weis;Douglas Fearon;Douglas Fearon;Young Whang

  • Toll-Like Receptor 2 Is Required for Innate, But Not Acquired, Host Defense to Borrelia burgdorferi

    R. Mark Wooten;Ying Ma;R. Alyson Yoder;Jeanette P. Brown

  • Identification of a 145,000 Mr membrane protein as the C3d receptor (CR2) of human B lymphocytes.

    Janis J. Weis;Thomas F. Tedder;Douglas T. Fearon

  • Rapid and sensitive quantification of Borrelia burgdorferi-infected mouse tissues by continuous fluorescent monitoring of PCR.

    Tom B. Morrison;Ying Ma;John H. Weis;Janis J. Weis

  • Borrelia burgdorferi outer surface lipoproteins OspA and OspB possess B-cell mitogenic and cytokine-stimulatory properties.

    Ying Ma;J. J. Weis

  • Intracellular localization of Borrelia burgdorferi within human endothelial cells.

    Ying Ma;A. Sturrock;J. J. Weis

  • Distinct Characteristics of Resistance to Borrelia burgdorferi-Induced Arthritis in C57BL/6N Mice

    Ying Ma;Kathleen Petri Seiler;Ernst J. Eichwald;John H. Weis

  • Dual role of interleukin-10 in murine Lyme disease: regulation of arthritis severity and host defense.

    Jeanette P. Brown;James F. Zachary;Cory Teuscher;Janis J. Weis

  • Heritable susceptibility to severe Borrelia burgdorferi-induced arthritis is dominant and is associated with persistence of large numbers of spirochetes in tissues.

    Liming Yang;J. H. Weis;E. Eichwald;C. P. Kolbert

  • MyD88 Plays a Unique Role in Host Defense but Not Arthritis Development in Lyme Disease

    Devin D. Bolz;Rhianna S. Sundsbak;Ying Ma;Shizuo Akira

  • Outer surface lipoproteins of Borrelia burgdorferi stimulate nitric oxide production by the cytokine-inducible pathway.

    Ying Ma;Kathleen Petri Seiler;Kuei-Fang Tai;Liming Yang

  • Saliva of the tick Ixodes dammini inhibits neutrophil function.

    JoséM.C. Ribeiro;Janis J. Weis;Sam R. Telford

  • Structure of the human B lymphocyte receptor for C3d and the Epstein-Barr virus and relatedness to other members of the family of C3/C4 binding proteins.

    J J Weis;L E Toothaker;J A Smith;J H Weis

  • The role of CD14 in signaling mediated by outer membrane lipoproteins of Borrelia burgdorferi

    R M Wooten;T B Morrison;J H Weis;S D Wright

  • Biological activities of native and recombinant Borrelia burgdorferi outer surface protein A: dependence on lipid modification.

    J. J. Weis;Ying Ma;L. F. Erdile

  • Resistance to Lyme disease in decorin-deficient mice

    Eric L. Brown;R. Mark Wooten;Barbara J.B. Johnson;Renato V. Iozzo

  • Delineating the Requirement for the Borrelia burgdorferi Virulence Factor OspC in the Mammalian Host

    Philip E. Stewart;Xiaohui Wang;Dawn M. Bueschel;Dawn R. Clifton

  • Identification of Quantitative Trait Loci Governing Arthritis Severity and Humoral Responses in the Murine Model of Lyme Disease

    Janis J. Weis;Barbara A. McCracken;Ying Ma;Daryl Fairbairn

  • Borrelia burgdorferi outer surface protein A (OspA) activates and primes human neutrophils.

    Tom B. Morrison;John H. Weis;Janis J. Weis

  • Host-pathogen interactions promoting inflammatory Lyme arthritis: use of mouse models for dissection of disease processes.

    R.Mark Wooten;Janis J Weis

Frequent Co-Authors

Douglas T. Fearon
Douglas T. Fearon Cold Spring Harbor Laboratory
Cory Teuscher
Cory Teuscher University of Vermont
Carsten J. Kirschning
Carsten J. Kirschning University of Duisburg-Essen
Robert B. Weiss
Robert B. Weiss University of Utah
Thomas F. Tedder
Thomas F. Tedder Duke University
Gerald J. Spangrude
Gerald J. Spangrude University of Utah
John A. Smith
John A. Smith University of Alabama at Birmingham
Diane M. Dunn
Diane M. Dunn University of Utah
Stefanie N. Vogel
Stefanie N. Vogel University of Maryland, Baltimore
Rebecca W. Doerge
Rebecca W. Doerge Carnegie Mellon University

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