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Medicine

D-Index
123
Citations
69213
World Ranking
3299
National Ranking
1816

Research.com Recognitions

  • 2020 - Fellow, National Academy of Inventors
  • 2008 - Distinguished Scientist Award, American Heart Association
  • 2002 - Member of the National Academy of Medicine (NAM)
  • 1999 - Member of the National Academy of Sciences
  • 1999 - Fellow of the American Academy of Arts and Sciences
  • 1998 - Nobel Prize for their discoveries concerning nitric oxide as a signalling molecule in the cardiovascular system

Overview

Louis J. Ignarro is affiliated with the University of California, Los Angeles in the United States. Their research primarily spans the field of Medicine, with a particular focus on several subfields including Oncology, Hepatology, Behavioral Neuroscience, Infectious Diseases, and Psychiatry and Mental Health.

They have contributed notably to topics such as Cancer Treatment and Pharmacology, Stress Responses and Cortisol, COVID-19 Clinical Research Studies, Cancer, Stress, Anesthesia, and Immune Response, Heme Oxygenase-1 and Carbon Monoxide, Nitric Oxide and Endothelin Effects, and High Altitude and Hypoxia.

Recent publications by Louis J. Ignarro include the following:

  • Inhaled NO and COVID-19, 2020, British Journal of Pharmacology
  • May Mangafodipir or Other SOD Mimetics Contribute to Better Care in COVID-19 Patients?, 2020, Antioxidants
  • The Damaging Outcome of the POLAR Phase III Trials Was Due to Avoidable Time-Dependent Redox Interaction between Oxaliplatin and PledOx, 2021, Antioxidants
  • Exacerbated Neuropathy in POLAR A and M Trials Due to Redox Interaction of PledOx-Associated Mn2+ and Oxaliplatin-Associated Pt2+, 2023, Antioxidants
  • Joint statement in support of hepatitis C human challenge studies, 2023, The Lancet. Gastroenterology & hepatology

Frequent co-authors working alongside Louis J. Ignarro include J. Karlsson, Per Jynge, Harvey J. Alter, Eleanor Barnes, and Mia J. Biondi.

The venues where they have commonly published their work include the journals Antioxidants, British Journal of Pharmacology, The Lancet. Gastroenterology & Hepatology, Science Advances, and Journal of Cancer Research.

Louis J. Ignarro's professional achievements are recognized through several awards. These include the Nobel Prize in 1998 for discoveries concerning nitric oxide as a signalling molecule in the cardiovascular system, membership in the National Academy of Sciences since 1999, fellowship in the American Academy of Arts and Sciences since 1999, membership in the National Academy of Medicine since 2002, the Distinguished Scientist Award from the American Heart Association in 2008, and fellowship in the National Academy of Inventors since 2020.

Best Publications

  • Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

    Louis J. Ignarro;Georgette M. Buga;Keith S. Wood;Russell E. Byrns

  • Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

    L J Ignarro;H Lippton;J C Edwards;W H Baricos

  • Biosynthesis and Metabolism of Endothelium-Derived Nitric Oxide

    Louis J. Ignarro

  • Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.

    L J Ignarro;R E Byrns;G M Buga;K S Wood

  • Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein.

    L J Ignarro

  • Nitric oxide : biology and pathobiology

    Louis J. Ignarro

  • Nitric Oxide as a Mediator of Relaxation of the Corpus Cavernosum in Response to Nonadrenergic, Noncholinergic Neurotransmission

    Jacob Rajfer;William J. Aronson;Peggy A. Bush;Frederick J. Dorey

  • Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle

    Louis J. Ignarro;Peggy A. Bush;Georgette M. Buga;Keith S. Wood

  • Nitric oxide as a signaling molecule in the vascular system: an overview.

    Louis J. Ignarro;Giuseppe Cirino;Alessandro Casini;Claudio Napoli

  • Endothelium-derived nitric oxide: actions and properties.

    Louis J. Ignarro

  • Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide.

    Jean E. Merrill;Louis J. Ignarro;Michael P. Sherman;Judy Melinek

  • NITRIC OXIDE AS A UNIQUE SIGNALING MOLECULE IN THE VASCULAR SYSTEM: A HISTORICAL OVERVIEW

    Louis J. Ignarro

  • Evidence for the inhibitory role of guanosine 3', 5'-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators

    BT Mellion;LJ Ignarro;EH Ohlstein;EG Pontecorvo

  • Signal transduction mechanisms involving nitric oxide

    Louis J. Ignarro

  • Relationship between cyclic guanosine 3':5'-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin.

    C A Gruetter;D Y Gruetter;J E Lyon;P J Kadowitz

  • Shear stress-induced release of nitric oxide from endothelial cells grown on beads.

    G M Buga;M E Gold;J M Fukuto;L J Ignarro

  • Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis

    Toshio Hayashi;Jon M. Fukuto;Louis J. Ignarro;Gautam Chaudhuri

  • Phase II Study of Pomegranate Juice for Men with Rising Prostate-Specific Antigen following Surgery or Radiation for Prostate Cancer

    Allan J. Pantuck;John T. Leppert;Nazy Zomorodian;William Aronson

  • Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: an overview.

    Louis J. Ignarro;Claudio Napoli;Joseph Loscalzo

  • Nutrition, physical activity, and cardiovascular disease: an update.

    Louis J. Ignarro;Maria Luisa Balestrieri;Claudio Napoli

Frequent Co-Authors

Claudio Napoli
Claudio Napoli University of Campania "Luigi Vanvitelli"
Gautam Chaudhuri
Gautam Chaudhuri University of California, Los Angeles
Jon M. Fukuto
Jon M. Fukuto Sonoma State University
Gerald D. Buckberg
Gerald D. Buckberg University of California, Los Angeles
Lilach O. Lerman
Lilach O. Lerman Mayo Clinic
Giuseppe Cirino
Giuseppe Cirino University of Naples Federico II
Antonio Giordano
Antonio Giordano Temple University
Michael S. Wolin
Michael S. Wolin New York Medical College
Jean E. Merrill
Jean E. Merrill University of California, Los Angeles
William J. Aronson
William J. Aronson University of California, Los Angeles

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