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Medicine

D-Index
97
Citations
47626
World Ranking
9109
National Ranking
4697

Overview

Galina K. Sukhova is a researcher affiliated with Harvard Medical School in the United States. Their work spans multiple fields, primarily focused on medicine, biochemistry, genetics and molecular biology, and immunology and microbiology. The subfields of study most associated with their research include immunology, molecular biology, cardiology and cardiovascular medicine, cancer research, and hematology.

The main topics explored in Sukhova's research encompass atherosclerosis and cardiovascular diseases, neutrophil, myeloperoxidase and oxidative mechanisms, extracellular vesicles in disease, cardiac fibrosis and remodeling, cell adhesion molecules research, cancer-related molecular mechanisms research, and IL-33, ST2, and ILC pathways.

The scientist's frequent coauthors reflect a network of collaboration in cardiovascular and molecular biology research. These include:

  • Peter Libby (17 publications)
  • Eugenia Shvartz (9 publications)
  • Amélie Vromman (7 publications)
  • Guo-Ping Shi (6 publications)
  • Grasiele Sausen (6 publications)

Publication venues where Sukhova's work appears most often include:

  • Circulation (8 publications)
  • Arteriosclerosis Thrombosis and Vascular Biology (4 publications)
  • Cardiovascular Research (2 publications)
  • Nature Communications (1 publication)
  • JCI Insight (1 publication)

Selected recent papers authored or coauthored by Sukhova are:

  • "Eosinophils improve cardiac function after myocardial infarction," 2020, Nature Communications
  • "Targeted delivery of protein arginine deiminase-4 inhibitors to limit arterial intimal NETosis and preserve endothelial integrity," 2021, Cardiovascular Research
  • "S100A9-RAGE Axis Accelerates Formation of Macrophage-Mediated Extracellular Vesicle Microcalcification in Diabetes Mellitus," 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • "IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation," 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • "LncRNA VINAS regulates atherosclerosis by modulating NF-κB and MAPK signaling," 2020, JCI Insight

Best Publications

  • Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.

    Z S Galis;Galina K. Sukhova;M W Lark;Peter Libby

  • Absence of Monocyte Chemoattractant Protein-1 Reduces Atherosclerosis in Low Density Lipoprotein Receptor–Deficient Mice

    Long Gu;Yoshikatsu Okada;Steven K. Clinton;Craig Gerard

  • Clonal Hematopoiesis and risk of atherosclerotic cardiovascular disease

    Siddhartha Jaiswal;Pradeep Natarajan;Pradeep Natarajan;Alexander J. Silver;Christopher J. Gibson

  • Reduction of atherosclerosis in mice by inhibition of CD40 signalling

    François Mach;Uwe Schönbeck;Galina K. Sukhova;Elizabeth Atkinson

  • Local proliferation dominates lesional macrophage accumulation in atherosclerosis

    Clinton S Robbins;Ingo Hilgendorf;Georg F Weber;Igor Theurl

  • Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis.

    François Mach;Uwe Schönbeck;Galina K. Sukhova;Todd Bourcier

  • Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes.

    Seigo Sugiyama;Yoshikatsu Okada;Galina K. Sukhova;Renu Virmani

  • Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells.

    Galina K. Sukhova;Guo Ping Shi;Daniel I. Simon;Harold A. Chapman

  • Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion.

    Z S Galis;M Muszynski;G K Sukhova;E Simon-Morrissey

  • Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice.

    Jian Liu;Adeline Divoux;Jiusong Sun;Jie Zhang

  • PPARα Activators Inhibit Cytokine-Induced Vascular Cell Adhesion Molecule-1 Expression in Human Endothelial Cells

    Nikolaus Marx;Galina K. Sukhova;Tucker Collins;Peter Libby

  • Evidence for Increased Collagenolysis by Interstitial Collagenases-1 and -3 in Vulnerable Human Atheromatous Plaques

    Sukhova Gk;Schönbeck U;Rabkin E;Schoen Fj

  • Macrophages in Human Atheroma Contain PPARγ: Differentiation-Dependent Peroxisomal Proliferator-Activated Receptor γ (PPARγ) Expression and Reduction of MMP-9 Activity through PPARγ Activation in Mononuclear Phagocytes in Vitro

    Nikolaus Marx;Galina Sukhova;Curran Murphy;Peter Libby

  • Chlamydial Heat Shock Protein 60 Localizes in Human Atheroma and Regulates Macrophage Tumor Necrosis Factor-α and Matrix Metalloproteinase Expression

    Amir Kol;Galina K. Sukhova;Andrew H. Lichtman;Peter Libby

  • Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases.

    Zorina S. Galis;Galina K. Sukhova;Roger Kranzhöfer;Stephen L. Clark

  • Lipid Lowering by Diet Reduces Matrix Metalloproteinase Activity and Increases Collagen Content of Rabbit Atheroma A Potential Mechanism of Lesion Stabilization

    Masanori Aikawa;Elena Rabkin;Yoshikatsu Okada;Sami J. Voglic

  • Macrophages and atherosclerotic plaque stability

    Peter Libby;Yong Jian Geng;Masanori Aikawa;Uwe Schoenbeck

  • Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for atherogenesis.

    Norbert Gerdes;Galina K. Sukhova;Peter Libby;Rebecca S. Reynolds

  • Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells

    François Mach;Alain Sauty;Albert S. Iarossi;Galina K. Sukhova

  • Cystatin C deficiency in human atherosclerosis and aortic aneurysms.

    Guo-Ping Shi;Galina K. Sukhova;Anders Grubb;Anique Ducharme

Frequent Co-Authors

Peter Libby
Peter Libby Brigham and Women's Hospital
Masanori Aikawa
Masanori Aikawa Brigham and Women's Hospital
Matthias Nahrendorf
Matthias Nahrendorf Harvard University
Elena Aikawa
Elena Aikawa Brigham and Women's Hospital
Andrew D. Luster
Andrew D. Luster Harvard University
Richard T. Lee
Richard T. Lee Harvard University
Andrew H. Lichtman
Andrew H. Lichtman Brigham and Women's Hospital
Filip K. Swirski
Filip K. Swirski Icahn School of Medicine at Mount Sinai
Harold A. Chapman
Harold A. Chapman University of California, San Francisco

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