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Biology and Biochemistry

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Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2013 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Eric R. Fearon is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily focuses on areas related to molecular biology, oncology, cancer research, immunology, and public health.

Their work covers a range of main topics including:

  • Immune cells in cancer
  • Epigenetics and DNA Methylation
  • Gut microbiota and health
  • Cancer, Hypoxia, and Metabolism
  • Ferroptosis and cancer prognosis
  • Cancer-related Molecular Pathways
  • Ovarian cancer diagnosis and treatment

Recent publications by Eric R. Fearon include:

  • "Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance," 2021, Cancer Cell
  • "Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer," 2022, Cell Metabolism
  • "Altering the Microbiome Inhibits Tumorigenesis in a Mouse Model of Oviductal High-Grade Serous Carcinoma," 2021, Cancer Research
  • "Aging accelerates while multiparity delays tumorigenesis in mouse models of high-grade serous carcinoma," 2022, Gynecologic Oncology
  • "Microenvironmental Ammonia Enhances T cell Exhaustion in Colorectal Cancer," 2022, bioRxiv (Cold Spring Harbor Laboratory)

Frequent coauthors associated with Fearon's research are:

  • Ruma Banerjee
  • Lila M. Gierasch
  • F. Peter Guengerich
  • Roger Colbran
  • Peter Cresswell

Their work is often published in the following venues:

  • Journal of Biological Chemistry
  • Cancer Research
  • Journal of Clinical Investigation
  • Clinical Cancer Research
  • Cancers

Eric R. Fearon has been recognized through memberships and fellowships including:

  • Fellow of the American Association for the Advancement of Science (AAAS), 2018
  • Member of the National Academy of Medicine (NAM), 2013
  • Member of the Association of American Physicians

Best Publications

  • A genetic model for colorectal tumorigenesis

    Eric R. Fearon;Bert Vogelstein

  • Genetic alterations during colorectal-tumor development.

    Bert Vogelstein;Eric R. Fearon;Stanley R. Hamilton;Scott E. Kern

  • Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

    Suzanne J. Baker;Eric R. Fearon;Janice M. Nigro;Stanley R. Hamilton

  • Prevalence of ras gene mutations in human colorectal cancers

    Johannes L. Bos;Matty Verlaan de Vries;Alex J. Van Der Eb;Eric R. Fearon

  • Suppression of human colorectal carcinoma cell growth by wild-type p53.

    Suzanne J. Baker;Sanford D Markowitz;Eric R. Fearon;James K V Willson

  • Identification of a chromosome 18q gene that is altered in colorectal cancers

    Eric R. Fearon;Kathleen R. Cho;Janice M. Nigro;Scott E. Kern

  • Molecular Genetics of Colorectal Cancer

    Eric R. Fearon

  • Mitogenic Signaling Mediated by Oxidants in Ras-Transformed Fibroblasts

    Kaikobad Irani;Yong Xia;Jay L. Zweier;Steven J. Sollott

  • Allelotype of colorectal carcinomas

    Bert Vogelstein;Eric R. Fearon;Scott E. Kern;Stanley R. Hamilton

  • p53-Mediated Activation of miRNA34 Candidate Tumor-Suppressor Genes

    Guido T. Bommer;Isabelle Gerin;Ying Feng;Andrew J. Kaczorowski

  • Heterogeneity in Cancer: Cancer Stem Cells versus Clonal Evolution

    Mark Shackleton;Elsa Quintana;Eric R. Fearon;Sean J. Morrison

  • Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth.

    Sergei I. Grivennikov;Kepeng Wang;Daniel Mucida;C. Andrew Stewart

  • The SLUG Zinc-Finger Protein Represses E-Cadherin in Breast Cancer

    Karen M. Hajra;David Y.S. Chen;Eric R. Fearon

  • Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

    Eric R. Fearon;Drew M. Pardoll;Toshiuki Itaya;Paul Golumbek

  • Clonal analysis of human colorectal tumors

    Eric R. Fearon;Stanley R. Hamilton;Bert Vogelstein

  • MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells.

    Qing Ji;Xinbao Hao;Xinbao Hao;Min Zhang;Wenhua Tang

  • Human Cancer Syndromes: Clues to the Origin and Nature of Cancer

    Eric R. Fearon

  • Mutation Spectrum and Genotype-Phenotype Analyses in Cowden Disease and Bannayan-Zonana Syndrome, Two Hamartoma Syndromes With Germline PTEN Mutation

    Debbie J. Marsh;Valérie Coulon;Kathryn L. Lunetta;Philippe Rocca-Serra

  • A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells.

    Jong In Yook;Xiao Yan Li;Ichiro Ota;Casey Hu

  • Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours.

    Eric R. Fearon;Bert Vogelstein;Andrew P. Feinberg

Frequent Co-Authors

Kathleen R. Cho
Kathleen R. Cho University of Michigan–Ann Arbor
Bert Vogelstein
Bert Vogelstein Johns Hopkins University
Rork Kuick
Rork Kuick University of Michigan–Ann Arbor
Thomas J. Giordano
Thomas J. Giordano University of Michigan–Ann Arbor
Joel K. Greenson
Joel K. Greenson University of Michigan–Ann Arbor
Stanley R. Hamilton
Stanley R. Hamilton City Of Hope National Medical Center
Stephen B. Gruber
Stephen B. Gruber City Of Hope National Medical Center
Jeremy M. G. Taylor
Jeremy M. G. Taylor University of Michigan–Ann Arbor
Suzanne J. Baker
Suzanne J. Baker St. Jude Children's Research Hospital
Gad Rennert
Gad Rennert Technion – Israel Institute of Technology

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