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Medicine

D-Index
86
Citations
29269
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14064
National Ranking
7135

Overview

Celina G. Kleer is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine.

Their work predominantly focuses on the following fields of study:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Kleer has contributed extensively to several subfields, including:

  • Molecular Biology
  • Cancer Research
  • Oncology
  • Biomedical Engineering
  • Genetics

The main research topics covered in their publications include:

  • Epigenetics and DNA Methylation
  • Cancer Cells and Metastasis
  • RNA modifications and cancer
  • Breast Cancer Treatment Studies
  • Nanoplatforms for cancer theranostics
  • Cancer Genomics and Diagnostics
  • Cancer, Hypoxia, and Metabolism

Celina G. Kleer has published numerous papers, with several recent notable ones listed below:

  • Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors, 2020, Nature Communications
  • Inhibition of 2-hydroxyglutarate elicits metabolic reprogramming and mutant IDH1 glioma immunity in mice, 2020, Journal of Clinical Investigation
  • Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression, 2022, Nature Communications
  • Noncanonical Functions of the Polycomb Group Protein EZH2 in Breast Cancer, 2021, American Journal Of Pathology
  • Regulation of EZH2 protein stability: new mechanisms, roles in tumorigenesis, and roads to the clinic, 2024, EBioMedicine

The scientist frequently publishes in the following venues:

  • Cancer Research
  • Nature Communications
  • EBioMedicine
  • Advanced Healthcare Materials
  • Applied immunohistochemistry & molecular morphology

Celina G. Kleer has collaborated extensively with several co-authors, including:

  • Maria E. González
  • Ahmad Eido
  • Sabra Djomehri
  • Sebastiano Andò
  • Shilpa R. Tekula

Best Publications

  • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome.

    Christophe Ginestier;Min Hee Hur;Emmanuelle Charafe-Jauffret;Florence Monville

  • EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

    Celina G. Kleer;Qi Cao;Sooryanarayana Varambally;Ronglai Shen

  • Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity

    Christine L. Chaffer;Nemanja D. Marjanovic;Tony Lee;George Bell

  • CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature

    Zhenhua Miao;Kathryn E. Luker;Bretton C. Summers;Rob Berahovich

  • Breast Cancer Stem Cells Are Regulated by Mesenchymal Stem Cells through Cytokine Networks

    Suling Liu;Christophe Ginestier;Sing J. Ou;Shawn G. Clouthier

  • Repression of E-cadherin by the polycomb group protein EZH2 in cancer

    Qi Cao;J. Yu;S. M. Dhanasekaran;J. H. Kim

  • BRCA1 regulates human mammary stem/progenitor cell fate

    Suling Liu;Christophe Ginestier;Emmanuelle Charafe-Jauffret;Hailey Foco

  • E-cadherin expression in primary carcinomas of the breast and its distant metastases.

    Paul J Kowalski;Mark A Rubin;Celina G Kleer

  • Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis.

    Quintin Pan;Celina G. Kleer;Kenneth L. Van Golen;Jennifer Irani

  • Discoidin domain receptor tyrosine kinases: new players in cancer progression.

    Rajeshwari R. Valiathan;Marta Marco;Birgit Leitinger;Celina G. Kleer

  • Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer

    Dan R. Robinson;Shanker Kalyana-Sundaram;Shanker Kalyana-Sundaram;Yi Mi Wu;Sunita Shankar

  • Alpha-Methylacyl-CoA racemase: a novel tumor marker over-expressed in several human cancers and their precursor lesions.

    Ming Zhou;Arul M. Chinnaiyan;Celina G. Kleer;Peter C. Lucas

  • Identification of GATA3 as a Breast Cancer Prognostic Marker by Global Gene Expression Meta-analysis

    Rohit Mehra;Sooryanarayana Varambally;Lei Ding;Ronglai Shen

  • Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression

    Zhao Qiu Wu;Xiao Yan Li;Casey Yuexian Hu;Michael Ford

  • An Absence of Stromal Caveolin-1 Expression Predicts Early Tumor Recurrence and Poor Clinical Outcome in Human Breast Cancers

    Agnieszka K. Witkiewicz;Abhijit Dasgupta;Federica Sotgia;Isabelle Mercier

  • Protocol for the Examination of Specimens From Patients With Invasive Carcinoma of the Breast

    Susan C. Lester;Shikha Bose;Yunn Yi Chen;James L. Connolly

  • Changes in surgical management resulting from case review at a breast cancer multidisciplinary tumor board

    Erika A. Newman;Amy B. Guest;Mark A. Helvie;Marilyn A. Roubidoux

  • Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer

    Wei Li;Takashi Tanikawa;Ilona Kryczek;Houjun Xia

  • Characterization of RhoC expression in benign and malignant breast disease: A potential new marker for small breast carcinomas with metastatic ability

    Celina G. Kleer;Kenneth L. Van Golen;Yanhong Zhang;Zhi Fen Wu

  • Molecular biology of breast cancer metastasis: Inflammatory breast cancer: clinical syndrome and molecular determinants

    Celina G Kleer;Kenneth L van Golen;Sofia D Merajver

Frequent Co-Authors

Sofia D. Merajver
Sofia D. Merajver University of Michigan–Ann Arbor
Lisa A. Newman
Lisa A. Newman Cornell University
Daniel F. Hayes
Daniel F. Hayes University of Michigan–Ann Arbor
Max S. Wicha
Max S. Wicha University of Michigan–Ann Arbor
Arul M. Chinnaiyan
Arul M. Chinnaiyan University of Michigan–Ann Arbor
Kent A. Griffith
Kent A. Griffith University of Michigan–Ann Arbor
Sooryanarayana Varambally
Sooryanarayana Varambally University of Alabama at Birmingham
Alfred E. Chang
Alfred E. Chang University of Michigan–Ann Arbor
Lori J. Pierce
Lori J. Pierce University of Michigan–Ann Arbor
Jun Yao
Jun Yao The University of Texas MD Anderson Cancer Center

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