World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
18767
World Ranking
12296
National Ranking
5258

Overview

Jun Yao is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily spans Medicine and Biochemistry, Genetics and Molecular Biology, with a focused emphasis on Molecular Biology, Immunology, and Oncology. The scientist's body of work includes investigations into cancer research, cell biology, and the mechanisms underlying immune responses.

The main topics of Jun Yao's research include:

  • Immune Cell Function and Interaction
  • Cancer-related molecular mechanisms research
  • RNA modifications and cancer
  • Pancreatic and Hepatic Oncology Research
  • Epigenetics and DNA Methylation
  • Ubiquitin and proteasome pathways
  • Immunotherapy and Immune Responses

Among recent publications, several notable papers reflect the scientist's contributions to cancer and immunotherapy fields:

  • "Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy," published in 2021 in Nature Communications
  • "TYRO3 induces anti-PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis," published in 2021 in Journal of Clinical Investigation
  • "The allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H1," published in 2021 in Cancer Cell
  • "TRPS1: a highly sensitive and specific marker for breast carcinoma, especially for triple-negative breast cancer," published in 2020 in Modern Pathology
  • "Targeting Glycosylated PD-1 Induces Potent Antitumor Immunity," published in 2020 in Cancer Research

Jun Yao frequently collaborates with other researchers, including:

  • Mien-Chie Hung
  • Dihua Yu
  • Haoqiang Ying
  • Yongkun Wei
  • Wantong Yao

The scientist's work is predominantly published in the following venues:

  • Cancer Research (13 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (6 publications)
  • Nature Communications (5 publications)
  • Journal of Clinical Investigation (4 publications)
  • Blood (3 publications)

Best Publications

  • The cancer genome atlas pan-cancer analysis project

    John N Weinstein;John N Weinstein;Eric A. Collisson;Gordon B Mills;Kenna R Mills Shaw;Kenna R Mills Shaw

  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways

    Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir

  • Molecular Definition of Breast Tumor Heterogeneity

    Michail Shipitsin;Lauren L. Campbell;Pedram Argani;Stanislawa Weremowicz

  • Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

    Lin Zhang;Siyuan Zhang;Siyuan Zhang;Jun Yao;Frank J. Lowery

  • Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

    Chia Wei Li;Seung Oe Lim;Weiya Xia;Heng Huan Lee

  • Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer.

    Chenfang Dong;Tingting Yuan;Yadi Wu;Yifan Wang

  • Integrative genomic approaches identify IKBKE as a breast cancer oncogene.

    Jesse S. Boehm;Jean J. Zhao;Jun Yao;So Young Kim

  • Distinct epigenetic changes in the stromal cells of breast cancers.

    Min Hu;Jun Yao;Li Cai;Kurt E Bachman

  • Regulation of In Situ to Invasive Breast Carcinoma Transition

    Min Qi Hu;Jun Yao;Danielle K. Carroll;Stanislawa Weremowicz

  • Disrupting the Interaction of BRD4 With Diacetylated Twist Suppresses Tumorigenesis in Basal-Like Breast Cancer

    Jian Shi;Yifan Wang;Yifan Wang;Lei Zeng;Yadi Wu

  • Overexpression of ErbB2 Blocks Taxol-Induced Apoptosis by Upregulation of p21Cip1, which Inhibits p34Cdc2 Kinase

    Dihua Yu;Tong Jing;Bolin Liu;Jun Yao

  • G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer

    Chenfang Dong;Yadi Wu;Jun Yao;Yifan Wang

  • Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1.

    Chia Wei Li;Seung Oe Lim;Ezra M. Chung;Yong Soo Kim

  • Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy.

    Riyao Yang;Linlin Sun;Linlin Sun;Ching Fei Li;Yu Han Wang;Yu Han Wang

  • Overexpression of the c-erbB-2 Gene Enhanced Intrinsic Metastasis Potential in Human Breast Cancer Cells without Increasing Their Transformation Abilities

    Ming Tan;Jun Yao;Dihua Yu

  • Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression.

    Qingsong Hu;Youqiong Ye;Li-Chuan Chan;Yajuan Li

  • A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis

    Chunlai Li;Shouyu Wang;Zhen Xing;Aifu Lin

  • Cell type-specific DNA methylation patterns in the human breast

    Noga Bloushtain-Qimron;Noga Bloushtain-Qimron;Jun Yao;Eric L. Snyder;Michail Shipitsin

  • Combined cDNA array comparative genomic hybridization and serial analysis of gene expression analysis of breast tumor progression

    Jun Yao;Stanislawa Weremowicz;Bin Feng;Robert C. Gentleman

  • Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-β1 in human breast cancer cells

    Jun Yao;Shunbin Xiong;Kristine Klos;Nina Nguyen

Frequent Co-Authors

Mien Chie Hung
Mien Chie Hung China Medical University
Dihua Yu
Dihua Yu The University of Texas MD Anderson Cancer Center
Kornelia Polyak
Kornelia Polyak Harvard University
Gabriel N. Hortobagyi
Gabriel N. Hortobagyi The University of Texas MD Anderson Cancer Center
Yongkun Wei
Yongkun Wei The University of Texas MD Anderson Cancer Center
Weiya Xia
Weiya Xia The University of Texas MD Anderson Cancer Center
Aysegul A. Sahin
Aysegul A. Sahin The University of Texas MD Anderson Cancer Center
Haoqiang Ying
Haoqiang Ying The University of Texas MD Anderson Cancer Center
Jihye Paik
Jihye Paik Cornell University
Leng Han
Leng Han Indiana University – Purdue University Indianapolis

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