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D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
43496
World Ranking
9945
National Ranking
4352

Research.com Recognitions

  • 2023 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Boyi Gan is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these domains, they have contributed extensively to Molecular Biology, Pulmonary and Respiratory Medicine, Cancer Research, Oncology, and Epidemiology.

Their research focuses on several main topics, including:

  • Ferroptosis and cancer prognosis
  • RNA modifications and cancer
  • Cancer, Lipids, and Metabolism
  • Epigenetics and DNA Methylation
  • Cancer, Hypoxia, and Metabolism
  • Cancer-related molecular mechanisms research
  • Autophagy in Disease and Therapy

Boyi Gan's work has been published frequently in several notable venues. The most recurrent journals include:

  • Nature Communications
  • Cancer Research
  • Protein & Cell
  • Nature Cell Biology
  • Molecular Cell

Among their recent publications are:

  • "Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy" (2020, Protein & Cell)
  • "Targeting ferroptosis as a vulnerability in cancer" (2022, Nature reviews. Cancer)
  • "DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer" (2021, Nature)
  • "The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression" (2020, Cell Research)
  • "Energy-stress-mediated AMPK activation inhibits ferroptosis" (2020, Nature Cell Biology)

They have collaborated frequently with several co-authors, notably:

  • Guang Lei
  • Xiaoguang Liu
  • Chao Mao
  • Hyemin Lee
  • Li Zhuang

Best Publications

  • Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

    Haoqiang Ying;Alec C. Kimmelman;Costas A. Lyssiotis;Sujun Hua

  • Targeting ferroptosis as a vulnerability in cancer

    Unknown

  • Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy

    Pranavi Koppula;Li Zhuang;Boyi Gan;Boyi Gan

  • DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer.

    Chao Mao;Xiaoguang Liu;Yilei Zhang;Guang Lei

  • The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression.

    Guang Lei;Guang Lei;Yilei Zhang;Pranavi Koppula;Xiaoguang Liu

  • Energy-stress-mediated AMPK activation inhibits ferroptosis.

    Hyemin Lee;Fereshteh Zandkarimi;Yilei Zhang;Jitendra Kumar Meena

  • BAP1 links metabolic regulation of ferroptosis to tumour suppression.

    Yilei Zhang;Jiejun Shi;Xiaoguang Liu;Li Feng

  • Long noncoding RNA MALAT1 suppresses breast cancer metastasis

    Jongchan Kim;Hai Long Piao;Hai Long Piao;Beom Jun Kim;Fan Yao

  • Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer.

    Pranavi Koppula;Pranavi Koppula;Yilei Zhang;Li Zhuang;Boyi Gan;Boyi Gan

  • Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis

  • AMPK modulates Hippo pathway activity to regulate energy homeostasis.

    Wenqi Wang;Zhen Dong Xiao;Xu Li;Kathryn E. Aziz

  • mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation

    Yilei Zhang;Robert V. Swanda;Litong Nie;Xiaoguang Liu

  • Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells

    Boyi Gan;Jian Hu;Shan Jiang;Yingchun Liu

  • Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis

    Huijun Wei;Shuang Wei;Boyi Gan;Xu Peng;Xu Peng

  • A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers

    Unknown

  • Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer.

    Xiaoguang Liu;Kellen Olszewski;Yilei Zhang;Esther W Lim

  • Mitochondrial regulation of ferroptosis.

    Boyi Gan

  • Antitelomerase Therapy Provokes ALT and Mitochondrial Adaptive Mechanisms in Cancer

    Jian Hu;Soyoon Sarah Hwang;Soyoon Sarah Hwang;Marc Liesa;Boyi Gan

  • PLAGL2 Regulates Wnt Signaling to Impede Differentiation in Neural Stem Cells and Gliomas

    Hongwu Zheng;Haoqiang Ying;Ruprecht Wiedemeyer;Haiyan Yan

  • A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

    Unknown

Frequent Co-Authors

Jun-Lin Guan
Jun-Lin Guan University of Cincinnati Medical Center
Ronald A. DePinho
Ronald A. DePinho The University of Texas MD Anderson Cancer Center
Haoqiang Ying
Haoqiang Ying The University of Texas MD Anderson Cancer Center
Wei Li
Wei Li Harvard University
Jihye Paik
Jihye Paik Cornell University
Alexei Protopopov
Alexei Protopopov The University of Texas MD Anderson Cancer Center
Han Liang
Han Liang The University of Texas MD Anderson Cancer Center
Lynda Chin
Lynda Chin The University of Texas Health Science Center at Houston
Leng Han
Leng Han Indiana University – Purdue University Indianapolis
Jianhua Zhang
Jianhua Zhang The University of Texas MD Anderson Cancer Center

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