World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
34759
World Ranking
5196
National Ranking
2470

Overview

Leng Han is affiliated with Indiana University - Purdue University Indianapolis in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with significant contributions to Medicine.

Their work is particularly focused on several subfields including Molecular Biology, Oncology, Cancer Research, Immunology, and Pulmonary and Respiratory Medicine. The major topics of Leng Han's studies involve RNA modifications and cancer, cancer immunotherapy and biomarkers, cancer-related molecular mechanisms research, epigenetics and DNA methylation, RNA research and splicing, ferroptosis and cancer prognosis, and immune cell function and interaction.

Leng Han has published research in various scientific venues. The most frequent publication venues include:

  • Nature Communications
  • Cancer Research
  • Biochemical and Biophysical Research Communications
  • Advanced Science
  • Trends in Cancer

Some of the recent papers associated with Leng Han include:

  • Single-cell and spatial analysis reveal interaction of FAP+ fibroblasts and SPP1+ macrophages in colorectal cancer (2022, Nature Communications)
  • Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein (2020, Autophagy)
  • Comprehensive molecular characterization of mitochondrial genomes in human cancers (2020, Nature Genetics)
  • Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function (2020, Nature Cell Biology)
  • YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis (2020, Cancer Cell)

Throughout their research career, Leng Han has collaborated extensively with several co-authors, including:

  • Youqiong Ye
  • Zhao Zhang
  • Lixia Diao
  • Yuan Liu
  • Ying Jing

Best Publications

  • The cancer genome atlas pan-cancer analysis project

    John N Weinstein;John N Weinstein;Eric A. Collisson;Gordon B Mills;Kenna R Mills Shaw;Kenna R Mills Shaw

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • GSCALite: a web server for gene set cancer analysis.

    Chun Jie Liu;Fei Fei Hu;Meng Xuan Xia;Leng Han

  • Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial Dilated Cardiomyopathy

    Ning Sun;Masayuki Yazawa;Jianwei Liu;Leng Han

  • Abnormal Calcium Handling Properties Underlie Familial Hypertrophic Cardiomyopathy Pathology in Patient-Specific Induced Pluripotent Stem Cells

    Feng Lan;Andrew S. Lee;Ping Liang;Veronica Sanchez-Freire

  • The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer

    Aifu Lin;Chunlai Li;Zhen Xing;Qingsong Hu

  • TANRIC: An Interactive Open Platform to Explore the Function of lncRNAs in Cancer.

    Jun Li;Leng Han;Paul Roebuck;Lixia Diao

  • The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers.

    Leng Han;Lixia Diao;Shuangxing Yu;Xiaoyan Xu;Xiaoyan Xu

  • Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer

    Yumeng Wang;Xiaoyan Xu;Dejan Maglic;Michael T Dill

  • Gene co-expression network analysis reveals common system-level properties of prognostic genes across cancer types

    Yang Yang;Leng Han;Yuan Yuan;Jun Li

  • Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function

    Li Wang;Peng Yu;Bingying Zhou;Jiangping Song

  • CSCD: a database for cancer-specific circular RNAs

    Siyu Xia;Jing Feng;Ke Chen;Yanbing Ma

  • Comprehensive characterization of tissue-specific circular RNAs in the human and mouse genomes

    Siyu Xia;Jing Feng;Lijun Lei;Jun Hu

  • Comprehensive molecular characterization of mitochondrial genomes in human cancers

    Yuan Yuan;Young Seok Ju;Youngwook Kim;Jun Li

  • Assessing the clinical utility of cancer genomic and proteomic data across tumor types

    Yuan Yuan;Eliezer M. Van Allen;Eliezer M. Van Allen;Larsson Omberg;Nikhil Wagle;Nikhil Wagle

  • Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression.

    Qingsong Hu;Youqiong Ye;Li-Chuan Chan;Yajuan Li

  • A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis

    Chunlai Li;Shouyu Wang;Zhen Xing;Aifu Lin

  • YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis

    Guoqiang Chang;Lei Shi;Youqiong Ye;Hailing Shi;Hailing Shi

  • The Cancer Genome Atlas Pan-Cancer analysis project

    Kyle Chang;Chad J Creighton;Caleb Davis;Lawrence Donehower

Frequent Co-Authors

Han Liang
Han Liang The University of Texas MD Anderson Cancer Center
Lixia Diao
Lixia Diao The University of Texas MD Anderson Cancer Center
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Zhongming Zhao
Zhongming Zhao The University of Texas Health Science Center at Houston
Mien Chie Hung
Mien Chie Hung China Medical University
Joseph C. Wu
Joseph C. Wu Stanford University
An-Yuan Guo
An-Yuan Guo Huazhong University of Science and Technology
Yang Xia
Yang Xia The University of Texas Health Science Center at Houston
David H. Hawke
David H. Hawke The University of Texas MD Anderson Cancer Center
John N. Weinstein
John N. Weinstein The University of Texas MD Anderson Cancer Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Leng Han

Trending Scientists

Recently Published Articles