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Biology and Biochemistry

D-Index
62
Citations
16480
World Ranking
10652
National Ranking
4630

Overview

David H. Hawke is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research spans multiple fields within biochemistry, genetics, molecular biology, and medicine, focusing extensively on molecular biology and oncology.

The primary areas of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields contributing to their research are:

  • Molecular Biology
  • Oncology
  • Cancer Research
  • Immunology
  • Cell Biology

David H. Hawke's work covers diverse topics such as:

  • Cancer-related molecular mechanisms research
  • Immunotherapy and Immune Responses
  • Vaccines and immunoinformatics approaches
  • Microtubule and mitosis dynamics
  • Muscle Physiology and Disorders
  • RNA Research and Splicing
  • Cancer Immunotherapy and Biomarkers

Their publication record includes articles in leading journals with a notable number of papers published in venues such as:

  • Nature Communications
  • Cancer Research
  • Nature Cell Biology
  • Science
  • Journal for ImmunoTherapy of Cancer

Representative recent papers authored or coauthored by David H. Hawke are:

  • The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin, 2020, Nature Cell Biology
  • A noncoding RNA modulator potentiates phenylalanine metabolism in mice, 2021, Science
  • Neoantigen vaccination induces clinical and immunologic responses in non-small cell lung cancer patients harboring EGFR mutations, 2021, Journal for ImmunoTherapy of Cancer
  • Functional significance of gain-of-function H19 lncRNA in skeletal muscle differentiation and anti-obesity effects, 2021, Genome Medicine
  • Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers, 2020, Nature Communications

Frequent collaborators in their scientific endeavors include:

  • Mien-Chie Hung
  • Chunru Lin
  • Amjad H. Talukder
  • Jason Roszik
  • Gregory Lizée

Best Publications

  • Phosphorylation of β-Catenin by AKT Promotes β-Catenin Transcriptional Activity *

    Dexing Fang;David Hawke;Yanhua Zheng;Yan Xia

  • PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis.

    Weiwei Yang;Yan Xia;David Hawke;Xinjian Li

  • A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response

    Hiroshi Masumoto;David Hawke;Ryuji Kobayashi;Alain Verreault

  • Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation.

    Koji Itahana;Krishna P. Bhat;Aiwen Jin;Yoko Itahana

  • The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer

    Aifu Lin;Chunlai Li;Zhen Xing;Qingsong Hu

  • Endothelial Cells Promote the Colorectal Cancer Stem Cell Phenotype through a Soluble Form of Jagged-1

    Jia Lu;Xiangcang Ye;Fan Fan;Ling Xia

  • LncRNA directs cooperative epigenetic regulation downstream of chemokine signals

    Zhen Xing;Aifu Lin;Chunlai Li;Ke Liang

  • Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis

    Xinjian Li;Yuhui Jiang;Jill Meisenhelder;Weiwei Yang

  • KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase.

    Yugang Wang;Yusong R. Guo;Ke Liu;Zheng Yin

  • Tyrosine phosphorylation controls PCNA function through protein stability.

    Shao Chun Wang;Yusuke Nakajima;Yusuke Nakajima;Yung Luen Yu;Weiya Xia

  • Measurement of DNA concentration as a normalization strategy for metabolomic data from adherent cell lines

    Leslie P. Silva;Philip L. Lorenzi;Preeti Purwaha;Valeda Yong

  • EGF-Induced ERK Activation Promotes CK2-Mediated Disassociation of α-Catenin from β-Catenin and Transactivation of β-Catenin

    Haitao Ji;Ji Wang;Heinz Nika;David Hawke

  • Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression.

    Qingsong Hu;Youqiong Ye;Li-Chuan Chan;Yajuan Li

  • Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes

    Konrad Gabrusiewicz;Xu Li;Jun Wei;Yuuri Hashimoto

  • A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis

    Chunlai Li;Shouyu Wang;Zhen Xing;Aifu Lin

  • Benchtop isolation and characterization of functional exosomes by sequential filtration.

    Mitja L. Heinemann;Matthias Ilmer;Leslie P. Silva;David H. Hawke

  • The amino acid sequence of a fluorescein-labeled peptide from the active site of (Na,K)-ATPase.

    R A Farley;C M Tran;C T Carilli;D Hawke

  • The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to hyperactivate AKT and confer resistance to AKT inhibitors.

    Aifu Lin;Qingsong Hu;Chunlai Li;Zhen Xing

  • Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy

    Xu Qian;Xinjian Li;Qingsong Cai;Chuanbao Zhang

  • Erratum: PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis ((Cell (2012) 150 (685â€"696))

    Weiwei Yang;Yan Xia;David Hawke;Xin-Jian Li

Frequent Co-Authors

Zhimin Lu
Zhimin Lu Zhejiang University
John E. Shively
John E. Shively City Of Hope National Medical Center
Mien Chie Hung
Mien Chie Hung China Medical University
Ryuji Kobayashi
Ryuji Kobayashi The University of Texas MD Anderson Cancer Center
Leng Han
Leng Han Indiana University – Purdue University Indianapolis
Xinjian Li
Xinjian Li Zhengzhou University of Light Industry
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Jason Roszik
Jason Roszik The University of Texas MD Anderson Cancer Center
Patrick Hwu
Patrick Hwu The University of Texas MD Anderson Cancer Center
Han Liang
Han Liang The University of Texas MD Anderson Cancer Center

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