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D-Index & Metrics

Molecular Biology

D-Index
78
Citations
24233
World Ranking
1072
National Ranking
16

Research.com Recognitions

  • 2017 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Zhimin Lu is affiliated with Zhejiang University in China and has an extensive body of scientific work primarily situated within the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Their research contributions cover a wide range of subfields including Molecular Biology, Cancer Research, Immunology, Physiology, and Epidemiology.

Their main research topics span several interrelated areas:

  • Cancer, Hypoxia, and Metabolism
  • RNA modifications and cancer
  • Metabolism, Diabetes, and Cancer
  • Epigenetics and DNA Methylation
  • Cancer, Lipids, and Metabolism
  • Ubiquitin and proteasome pathways
  • Immune cells in cancer

Zhimin Lu has published numerous papers in prominent scientific venues. Frequent publication outlets include:

  • Molecular Cell
  • Nature Communications
  • Nature Cell Biology
  • Nature Metabolism
  • Cancer Communications

Among the recent papers associated with this scientist are:

  • "Lipid metabolism and cancer," 2020, The Journal of Experimental Medicine
  • "The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis," 2020, Nature
  • "Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα," 2022, Cell Metabolism
  • "Engineered algae: A novel oxygen-generating system for effective treatment of hypoxic cancer," 2020, Science Advances
  • "The Evolving Landscape of Noncanonical Functions of Metabolic Enzymes in Cancer and Other Pathologies," 2021, Cell Metabolism

Collaboration forms a significant part of Zhimin Lu's research activities, with frequent co-authors including Ying Meng, Dong Guo, Daqian Xu, Shudi Luo, and Hongfei Jiang. This collaboration network reflects the interdisciplinary and multifaceted nature of their work.

Zhimin Lu was recognized with the honor of becoming a Fellow of the American Association for the Advancement of Science (AAAS) in 2017.

Best Publications

  • Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

    Weiwei Yang;Yan Xia;Haitao Ji;Yanhua Zheng

  • Phosphorylation of β-Catenin by AKT Promotes β-Catenin Transcriptional Activity *

    Dexing Fang;David Hawke;Yanhua Zheng;Yan Xia

  • ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

    Weiwei Yang;Yanhua Zheng;Yan Xia;Haitao Ji

  • Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion

    Zhimin Lu;Sourav Ghosh;Zhiyong Wang;Tony Hunter

  • PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis.

    Weiwei Yang;Yan Xia;David Hawke;Xinjian Li

  • ERK1/2 MAP kinases in cell survival and apoptosis

    Zhimin Lu;Shuichan Xu

  • Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1

    Bing-Hua Jiang;Guoqiang Jiang;Jenny Z. Zheng;Zhimin Lu

  • New tumor markers: CA125 and beyond

    Robert C. Bast;D. Badgwell;Z. Lu;R. Marquez

  • Lipid metabolism and cancer.

    Xueli Bian;Rui Liu;Ying Meng;Dongming Xing;Dongming Xing

  • Epidermal Growth Factor-Induced Tumor Cell Invasion and Metastasis Initiated by Dephosphorylation and Downregulation of Focal Adhesion Kinase

    Zhimin Lu;Guoqiang Jiang;Peter Blume-Jensen;Tony Hunter

  • Activation of Protein Kinase C Triggers Its Ubiquitination and Degradation

    Zhimin Lu;David Liu;Armand Hornia;Wayne Devonish

  • Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis

    Xinjian Li;Yuhui Jiang;Jill Meisenhelder;Weiwei Yang

  • The PHD Domain of MEKK1 Acts as an E3 Ubiquitin Ligase and Mediates Ubiquitination and Degradation of ERK1/2

    Zhimin Lu;Shuichan Xu;Claudio Joazeiro;Melanie H Cobb

  • KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase.

    Yugang Wang;Yusong R. Guo;Ke Liu;Zheng Yin

  • Regulation of chromatin and gene expression by metabolic enzymes and metabolites

    Xinjian Li;Gabor Egervari;Yugang Wang;Shelley L. Berger

  • Involvement of Ral GTPase in v-Src-induced phospholipase D activation

    Hong Jiang;Jing-Qing Luo;Takeshi Urano;Paul Frankel

  • EGF-Induced ERK Activation Promotes CK2-Mediated Disassociation of α-Catenin from β-Catenin and Transactivation of β-Catenin

    Haitao Ji;Ji Wang;Heinz Nika;David Hawke

  • Tumor promotion by depleting cells of protein kinase C delta.

    Zhimin Lu;Armand Hornia;You Wei Jiang;You Wei Jiang;Qun Zang

  • Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy

    Xinjian Li;Willie Yu;Xu Qian;Yan Xia

  • Erratum: PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis ((Cell (2012) 150 (685â€"696))

    Weiwei Yang;Yan Xia;David Hawke;Xin-Jian Li

Frequent Co-Authors

Xinjian Li
Xinjian Li Zhengzhou University of Light Industry
Tony Hunter
Tony Hunter Salk Institute for Biological Studies
David H. Hawke
David H. Hawke The University of Texas MD Anderson Cancer Center
David A. Foster
David A. Foster City University of New York
Bing-Hua Jiang
Bing-Hua Jiang Zhengzhou University
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Hong Jiang
Hong Jiang Central South University
Larry A. Feig
Larry A. Feig Tufts University
Qianming Chen
Qianming Chen Sichuan University
Gilbert J. Cote
Gilbert J. Cote The University of Texas MD Anderson Cancer Center

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