2017 - Fellow of the American Association for the Advancement of Science (AAAS)
Zhimin Lu focuses on Cancer research, Cell biology, PKM2, Epidermal growth factor and Phosphorylation. His work carried out in the field of Cancer research brings together such families of science as Histone H3, Ubiquitin, Histone methyltransferase, Histone deacetylase 5 and Histone H2A. His study in Cell biology is interdisciplinary in nature, drawing from both Molecular biology and Warburg effect.
His PKM2 research incorporates themes from Phosphoglycerate kinase 1 and Pyruvate dehydrogenase kinase, Pyruvate dehydrogenase phosphatase, Pyruvate dehydrogenase lipoamide kinase isozyme 1, Pyruvate dehydrogenase complex. His Epidermal growth factor study integrates concerns from other disciplines, such as Signal transduction and Downregulation and upregulation. His research in Phosphorylation intersects with topics in Beta-catenin, Wnt signaling pathway and Catenin.
Cell biology, Cancer research, Phosphorylation, Protein kinase A and Kinase are his primary areas of study. His Cell biology research includes elements of Molecular biology, Downregulation and upregulation, Cell growth and PKM2. His research integrates issues of Epidermal growth factor, Cancer cell, Carcinogenesis, Transactivation and Signal transduction in his study of Cancer research.
His Transactivation research includes themes of Wnt signaling pathway and Catenin. His Phosphorylation research is multidisciplinary, incorporating elements of Anaerobic glycolysis and Phosphoglycerate kinase 1. His Kinase study combines topics in areas such as Fructokinase and Mitosis.
His primary scientific interests are in Cell biology, Cancer research, Phosphorylation, Protein kinase A and Cancer cell. Zhimin Lu studies Reactive oxygen species which is a part of Cell biology. His work deals with themes such as Immunohistochemistry, Cancer, CRISPR, Telomerase and Hedgehog signaling pathway, which intersect with Cancer research.
The concepts of his Phosphorylation study are interwoven with issues in Glycolysis, Phosphoglycerate kinase 1, Kinase and PTEN. His Protein kinase A research focuses on subjects like PCK1, which are linked to Lipogenesis, Sterol regulatory element-binding protein, Protein kinase B, Protein phosphorylation and Epidermal growth factor receptor. His Downregulation and upregulation course of study focuses on Promoter and Wnt signaling pathway and Catenin.
His main research concerns Protein kinase A, Cell biology, Cancer cell, Cancer research and Kinase. His Protein kinase A research integrates issues from Protein kinase B, PCK1, Sterol regulatory element-binding protein and Golgi apparatus, Endoplasmic reticulum. Zhimin Lu studies Cell biology, focusing on Transport protein in particular.
His Cancer research research is multidisciplinary, relying on both Tumor progression, Cancer, Cancer stem cell and Regulation of gene expression. His Kinase research incorporates elements of Glycolysis, Phosphoglycerate kinase 1, PTEN and Phosphorylation. His Phosphorylation research includes elements of Carcinogenesis and Cell growth.
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Phosphorylation of β-Catenin by AKT Promotes β-Catenin Transcriptional Activity *
Dexing Fang;David Hawke;Yanhua Zheng;Yan Xia.
Journal of Biological Chemistry (2007)
Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
Weiwei Yang;Yan Xia;Haitao Ji;Yanhua Zheng.
Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion
Zhimin Lu;Sourav Ghosh;Zhiyong Wang;Tony Hunter.
Cancer Cell (2003)
Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1
Bing-Hua Jiang;Guoqiang Jiang;Jenny Z. Zheng;Zhimin Lu.
Cell Growth & Differentiation (2001)
ERK1/2 MAP kinases in cell survival and apoptosis
Zhimin Lu;Shuichan Xu.
Iubmb Life (2006)
ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
Weiwei Yang;Yanhua Zheng;Yan Xia;Haitao Ji.
Nature Cell Biology (2012)
PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis.
Weiwei Yang;Yan Xia;David Hawke;Xinjian Li.
New tumor markers: CA125 and beyond
Robert C. Bast;D. Badgwell;Z. Lu;R. Marquez.
International Journal of Gynecological Cancer (2005)
Epidermal Growth Factor-Induced Tumor Cell Invasion and Metastasis Initiated by Dephosphorylation and Downregulation of Focal Adhesion Kinase
Zhimin Lu;Guoqiang Jiang;Peter Blume-Jensen;Tony Hunter.
Molecular and Cellular Biology (2001)
Activation of Protein Kinase C Triggers Its Ubiquitination and Degradation
Zhimin Lu;David Liu;Armand Hornia;Wayne Devonish.
Molecular and Cellular Biology (1998)
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