World's Best Scientists 2026 revealed!
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Best Female Scientists
2025

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Best Female Scientists

D-Index
121
Citations
51135
World Ranking
535
National Ranking
319

Medicine

D-Index
122
Citations
51967
World Ranking
3493
National Ranking
1922

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award

Overview

Aysegul A. Sahin is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily focuses on medical and molecular biology fields, with a significant emphasis on oncology and cancer research.

Their recent publications cover a range of topics related to cancer biology and pathology, including the classification and markers of breast carcinoma and mechanisms of tumor immune regulation. Notable papers include:

  • "The 2019 World Health Organization classification of tumours of the breast," 2020, Histopathology
  • "TRPS1: a highly sensitive and specific marker for breast carcinoma, especially for triple-negative breast cancer," 2020, Modern Pathology
  • "TRPS1, GATA3, and SOX10 expression in triple-negative breast carcinoma," 2022, Human Pathology
  • "CD8+ T cells inhibit metastasis and CXCL4 regulates its function," 2021, British Journal of Cancer
  • "Tumor-associated nonmyelinating Schwann cell-expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion," 2023, Science Advances

The scientist collaborates frequently with several researchers, including:

  • Lei Huo
  • Qingqing Ding
  • Hui Chen
  • Constance T. Albarracin
  • Kelly K. Hunt

Publications by Aysegul A. Sahin often appear in the following venues:

  • Cancer Research
  • Human Pathology
  • Cancers
  • Modern Pathology
  • Clinical Cancer Research

Their research spans multiple fields of study, predominantly:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields of focus include:

  • Oncology
  • Cancer Research
  • Pathology and Forensic Medicine
  • Pulmonary and Respiratory Medicine
  • Molecular Biology

Major research topics covered by their work are:

  • Breast Cancer Treatment Studies
  • Breast Lesions and Carcinomas
  • HER2/EGFR in Cancer Research
  • Cancer and Skin Lesions
  • Cancer Cells and Metastasis
  • Cancer Genomics and Diagnostics
  • Metastasis and carcinoma case studies

Best Publications

  • PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients

    Yoichi Nagata;Keng Hsueh Lan;Xiaoyan Zhou;Ming Tan

  • Significantly Higher Pathologic Complete Remission Rate After Neoadjuvant Therapy With Trastuzumab, Paclitaxel, and Epirubicin Chemotherapy: Results of a Randomized Trial in Human Epidermal Growth Factor Receptor 2–Positive Operable Breast Cancer

    Aman U. Buzdar;Nuhad K. Ibrahim;Deborah Francis;Daniel J. Booser

  • Tumour amplified kinase STK15 / BTAK induces centrosome amplification, aneuploidy and transformation

    Hongyi Zhou;Jian Kuang;Ling Zhong;Wen Lin Kuo

  • An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer.

    Katherine Stemke-Hale;Ana Maria Gonzalez-Angulo;Ana Lluch;Richard M. Neve

  • Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

    Lin Zhang;Siyuan Zhang;Siyuan Zhang;Jun Yao;Frank J. Lowery

  • Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics.

    Bryan T. Hennessy;Ana Maria Gonzalez-Angulo;Katherine Stemke-Hale;Michael Z. Gilcrease

  • Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

    Chia Wei Li;Seung Oe Lim;Weiya Xia;Heng Huan Lee

  • IKKβ Suppression of TSC1 Links Inflammation and Tumor Angiogenesis via the mTOR Pathway

    Dung Fang Lee;Hsu Ping Kuo;Hsu Ping Kuo;Chun Te Chen;Chun Te Chen;Jung Mao Hsu;Jung Mao Hsu

  • ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

    Jer Yen Yang;Cong S. Zong;Weiya Xia;Hirohito Yamaguchi

  • Deubiquitination and Stabilization of PD-L1 by CSN5

    Seung Oe Lim;Chia Wei Li;Weiya Xia;Jong Ho Cha

  • AKT-Independent Signaling Downstream of Oncogenic PIK3CA Mutations in Human Cancer

    Krishna M. Vasudevan;David A. Barbie;David A. Barbie;Michael A. Davies;Rosalia Rabinovsky

  • Benign Breast Diseases: Classification, Diagnosis, and Management

    Merih Guray;Aysegul A. Sahin

  • The 2019 World Health Organization classification of tumours of the breast.

    Puay Hoon Tan;Ian Ellis;Kimberly Allison;Edi Brogi

  • Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways

    Siyuan Zhang;Wen Chien Huang;Ping Li;Hua Guo

  • Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance

    Eswaran Devarajan;Aysegul A. Sahin;Jack S. Chen;Raghu R. Krishnamurthy

  • High risk of recurrence for patients with breast cancer who have human epidermal growth factor receptor 2-positive, node-negative tumors 1 cm or smaller.

    Ana Maria Gonzalez-Angulo;Jennifer K Litton;Kristine R Broglio;Funda Meric-Bernstam

  • Cyclooxygenase-2 expression in human breast cancers and adjacent ductal carcinoma in situ

    Elizabeth Half;Xi Ming Tang;Karin Gwyn;Aysegul A Sahin

  • Weekly Paclitaxel Improves Pathologic Complete Remission in Operable Breast Cancer When Compared With Paclitaxel Once Every 3 Weeks

    Marjorie C. Green;Aman U. Buzdar;Terry Smith;Nuhad K. Ibrahim

  • Outcome After Pathologic Complete Eradication of Cytologically Proven Breast Cancer Axillary Node Metastases Following Primary Chemotherapy

    Bryan T. Hennessy;Gabriel N. Hortobagyi;Roman Rouzier;Henry Kuerer

  • PTEN activation contributes to tumor inhibition by trastuzumab and loss of PTEN predicts trastuzumab resistance in patients.

    Keng-Hsueh Lan;Yoichi Nagata;Xiaoyan Zhou;Francisco J. Esteva

Frequent Co-Authors

Gabriel N. Hortobagyi
Gabriel N. Hortobagyi The University of Texas MD Anderson Cancer Center
Kelly K. Hunt
Kelly K. Hunt The University of Texas MD Anderson Cancer Center
Funda Meric-Bernstam
Funda Meric-Bernstam The University of Texas MD Anderson Cancer Center
Henry Mark Kuerer
Henry Mark Kuerer The University of Texas MD Anderson Cancer Center
Thomas A. Buchholz
Thomas A. Buchholz The University of Texas MD Anderson Cancer Center
Nour Sneige
Nour Sneige The University of Texas MD Anderson Cancer Center
Ana M. Gonzalez-Angulo
Ana M. Gonzalez-Angulo The University of Texas MD Anderson Cancer Center
Elizabeth A. Mittendorf
Elizabeth A. Mittendorf Brigham and Women's Hospital
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Melissa L. Bondy
Melissa L. Bondy Stanford University

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