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Biology and Biochemistry

D-Index
60
Citations
12210
World Ranking
12010
National Ranking
925

Overview

Paul N. Bishop is affiliated with the University of Manchester in the United Kingdom. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on subfields such as Ophthalmology, Radiology, Nuclear Medicine and Imaging, Molecular Biology, Cancer Research, and Immunology.

The main topics addressed in their work include retinal diseases and treatments, retinal imaging and analysis, glaucoma and retinal disorders, retinal development and disorders, retinal and optic conditions, cancer genomics and diagnostics, and the complement system in diseases.

Paul N. Bishop has contributed to several recent papers, including:

  • A foundation model for generalizable disease detection from retinal images, 2023, Nature
  • Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA, 2023, Nature
  • Genomic-transcriptomic evolution in lung cancer and metastasis, 2023, Nature
  • Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration, 2020, Nature Communications
  • Body composition and lung cancer-associated cachexia in TRACERx, 2023, Nature Medicine

The scientist frequently publishes with co-authors including Paul J. Foster, Anthony P. Khawaja, Sharon Chua, Cathy Williams, and Tünde Pető.

Regular publication venues for their research include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Lung Cancer
  • Nature
  • Nature Communications
  • Nature Medicine

Best Publications

  • Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

    Nicholas McGranahan;Rachel Rosenthal;Crispin T. Hiley;Crispin T. Hiley;Andrew J. Rowan

  • Seven new loci associated with age-related macular degeneration

    Lars G. Fritsche;Lars G. Fritsche;Wei Chen;Wei Chen;Matthew Schu;Brian L. Yaspan

  • Structural macromolecules and supramolecular organisation of the vitreous gel.

    Paul N Bishop

  • Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.

    Frederick Arce Vargas;Andrew J.S. Furness;Andrew J.S. Furness;Isabelle Solomon;Kroopa Joshi;Kroopa Joshi

  • Comprehensive validation of cardiovascular magnetic resonance techniques for the assessment of myocardial extracellular volume.

    Christopher A. Miller;Josephine H. Naish;Paul Bishop;Glyn Coutts

  • Adult vitreous structure and postnatal changes

    M M Le Goff;P N Bishop

  • Comparison of echocardiographic markers of right ventricular function in determining prognosis in chronic pulmonary disease.

    Malcolm I. Burgess;Nesrin Mogulkoc;Rowland J. Bright-Thomas;Paul Bishop

  • Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan

    Paul G. Scott;Paul A. McEwan;Carole M. Dodd;Ernst M. Bergmann

  • Structural correlations in the family of small leucine-rich repeat proteins and proteoglycans.

    Paul A. McEwan;Paul G. Scott;Paul N. Bishop;Jordi Bella

  • Age-Related Changes on the Surface of Vitreous Collagen Fibrils

    Paul N. Bishop;Paul N. Bishop;David F. Holmes;Karl E. Kadler;David McLeod

  • Impaired Binding of the Age-related Macular Degeneration-associated Complement Factor H 402H Allotype to Bruch's Membrane in Human Retina

    Simon J. Clark;Rahat Perveen;Rahat Perveen;Svetlana Hakobyan;B. Paul Morgan

  • Restoration of Vision with Ectopic Expression of Human Rod Opsin.

    Jasmina Cehajic-Kapetanovic;Cyril Eleftheriou;Annette E. Allen;Nina Milosavljevic

  • Tissue-Specific Host Recognition by Complement Factor H Is Mediated by Differential Activities of Its Glycosaminoglycan-Binding Regions

    Simon J. Clark;Liam A. Ridge;Andrew P. Herbert;Svetlana Hakobyan

  • Iron, zinc, and copper in retinal physiology and disease

    Marta Ugarte;Neville N. Osborne;Laurence A. Brown;Paul N. Bishop

  • Molecular findings from 537 individuals with inherited retinal disease

    Jamie M Ellingford;Jamie M Ellingford;Stephanie Barton;Sanjeev Bhaskar;James O'Sullivan;James O'Sullivan

  • Identification in Vitreous and Molecular Cloning of Opticin, a Novel Member of the Family of Leucine-rich Repeat Proteins of the Extracellular Matrix

    Anthony J. Reardon;Anthony J. Reardon;Magali Le Goff;Magali Le Goff;Michael D. Briggs;David McLeod

  • The biochemical structure of mammalian vitreous

    Paul Bishop

  • Matrix metalloproteinase-1 associates with intracellular organelles and confers resistance to lamin A/C Degradation during apoptosis

    G. Astrid Limb;Karl Matter;Gillian Murphy;Alison D. Cambrey

  • Age-related macular degeneration and the role of the complement system.

    Selina McHarg;Simon John Clark;Anthony John Day;Paul Nicholas Bishop;Paul Nicholas Bishop

  • Whole Genome Sequencing Increases Molecular Diagnostic Yield Compared with Current Diagnostic Testing for Inherited Retinal Disease

    Jamie M. Ellingford;Stephanie Barton;Sanjeev Bhaskar;Simon G. Williams

Frequent Co-Authors

Anthony J. Day
Anthony J. Day University of Manchester
Graeme C.M. Black
Graeme C.M. Black University of Manchester
John R.W. Yates
John R.W. Yates University of Cambridge
Robert J. Lucas
Robert J. Lucas University of Manchester
Anthony T. Moore
Anthony T. Moore University of California, San Francisco
Paul G. Scott
Paul G. Scott University of Alberta
Garth J. S. Cooper
Garth J. S. Cooper University of Auckland
Andrew J. Lotery
Andrew J. Lotery University of Southampton
Martin J. Humphries
Martin J. Humphries University of Manchester
John K. Sheehan
John K. Sheehan University of North Carolina at Chapel Hill

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