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Biology and Biochemistry

D-Index
78
Citations
18646
World Ranking
4625
National Ranking
2246

Research.com Recognitions

  • 2015 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Ratna K. Vadlamudi is affiliated with The University of Texas at Austin in the United States. Their research spans multiple fields including Biochemistry, Genetics and Molecular Biology, and Medicine, with an emphasis on Molecular Biology, Oncology, Genetics, Cancer Research, and Immunology as subfields.

The scientist's work covers several main topics such as:

  • Estrogen and related hormone effects
  • Cytokine Signaling Pathways and Interactions
  • Cancer Immunotherapy and Biomarkers
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Histone Deacetylase Inhibitors Research
  • Epigenetics and DNA Methylation

Vadlamudi has published extensively in venues that include:

  • Cancer Research
  • Cancers
  • Neuro-Oncology
  • International Journal of Molecular Sciences
  • Molecular Cancer Therapeutics

Notable recent papers comprise:

  • Programmed death ligand 1 signals in cancer cells, 2022, Nature reviews. Cancer
  • Brain-derived estrogen and neural function, 2021, Neuroscience & Biobehavioral Reviews
  • Astrocyte-Derived Estrogen Regulates Reactive Astrogliosis and is Neuroprotective following Ischemic Brain Injury, 2020, Journal of Neuroscience
  • Neuron-Derived Estrogen Is Critical for Astrocyte Activation and Neuroprotection of the Ischemic Brain, 2020, Journal of Neuroscience
  • M6A RNA Methylation Regulates Histone Ubiquitination to Support Cancer Growth and Progression, 2022, Cancer Research

Frequent collaborators include:

  • Suryavathi Viswanadhapalli
  • Uday P. Pratap
  • Gangadhara R. Sareddy
  • Rajeshwar R. Tekmal
  • Manjeet K. Rao

Recognition for their work includes being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2015.

Best Publications

  • Cloning and Expression of a Receptor for an Insecticidal Toxin of Bacillus thuringiensis

    Ratna K. Vadlamudi;Eric Weber;Inhae Ji;Tae H. Ji

  • Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor

    Abhijit Mazumdar;Rui-An Wang;Sandip K. Mishra;Liana Adam

  • NADPH oxidase in brain injury and neurodegenerative disorders.

    Merry W. Ma;Merry W. Ma;Jing Wang;Jing Wang;Quanguang Zhang;Quanguang Zhang;Ruimin Wang;Ruimin Wang

  • Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1

    Ratna K. Vadlamudi;Feng Li;Liana Adam;Diep Nguyen

  • Tumor-intrinsic PD-L1 signals regulate cell growth, pathogenesis and autophagy in ovarian cancer and melanoma

    Curtis A Clark;Harshita Gupta;Gangadhara R. Sareddy;Srilakshmi Pandeswara

  • Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase.

    Liana Adam;Ratna Vadlamudi;Sudhir Babu Kondapaka;Jonathan Chernoff

  • p62, a Phosphotyrosine-independent Ligand of the SH2 Domain of p56lck, Belongs to a New Class of Ubiquitin-binding Proteins

    Ratna K. Vadlamudi;Insil Joung;Jack L. Strominger;Jaekyoon Shin

  • Pak1 phosphorylation of snail, a master regulator of epithelial-to-mesenchyme transition, modulates snail's subcellular localization and functions.

    Zhibo Yang;Suresh Rayala;Diep Nguyen;Ratna K. Vadlamudi

  • Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells.

    Ratna K. Vadlamudi;Liana Adam;Rui-An Wang;Mahitosh Mandal

  • Regulation of cyclooxygenase-2 pathway by HER2 receptor

    Ratna K Vadlamudi;Mahitosh Mandal;Liana Adam;Gideon Steinbach

  • A naturally occurring MTA1 variant sequesters oestrogen receptor-α in the cytoplasm

    Rakesh Kumar;Rui An Wang;Abhijit Mazumdar;Amjad H. Talukder

  • Estrogen attenuates ischemic oxidative damage via an estrogen receptor α-mediated inhibition of NADPH oxidase activation

    Quan Guang Zhang;Limor Raz;Ruimin Wang;Dong Han

  • A specific binding protein from Manduca sexta for the insecticidal toxin of Bacillus thuringiensis subsp. berliner.

    Ratna K. Vadlamudi;Tae H. Ji;Lee A. Bulla

  • p21-activated Kinase-1 Signaling Mediates Cyclin D1 Expression in Mammary Epithelial and Cancer Cells

    Seetharaman Balasenthil;Aysegul A. Sahin;Christopher J. Barnes;Rui An Wang

  • Rapid estrogen signaling in the brain

    Limor Raz;Mohammad M. Khan;Virendra B. Mahesh;Ratna K. Vadlamudi

  • Role of Estrogen Receptor Signaling in Breast Cancer Metastasis

    Sudipa Saha Roy;Ratna K. Vadlamudi

  • P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-α and promotes hyperplasia in mammary epithelium

    Rui An Wang;Abhijit Mazumdar;Ratna K. Vadlamudi;Rakesh Kumar

  • Molecular Cloning and Characterization of PELP1, a Novel Human Coregulator of Estrogen Receptor α

    Ratna K. Vadlamudi;Rui An Wang;Abhijit Mazumdar;Yoon Sok Kim

  • Dynein light chain 1, a p21-activated kinase 1-interacting substrate, promotes cancerous phenotypes.

    Ratna K Vadlamudi;Rozita Bagheri-Yarmand;Zhibo Yang;Seetharaman Balasenthil

  • Regulation of microfilament reorganization and invasiveness of breast cancer cells by kinase dead p21-activated kinase-1.

    Liana Adam;Ratna K Vadlamudi;Mahitosh Mandal;Jonathan Chernoff

Frequent Co-Authors

Rakesh Kumar
Rakesh Kumar The University of Texas MD Anderson Cancer Center
Darrell W. Brann
Darrell W. Brann Augusta University
Quanguang Zhang
Quanguang Zhang Augusta University
Tyler J. Curiel
Tyler J. Curiel The University of Texas at San Antonio
Mahitosh Mandal
Mahitosh Mandal Indian Institute of Technology Kharagpur
Takayoshi Suzuki
Takayoshi Suzuki Osaka University
Aysegul A. Sahin
Aysegul A. Sahin The University of Texas MD Anderson Cancer Center
Anil K. Sood
Anil K. Sood The University of Texas MD Anderson Cancer Center
Lee A. Bulla
Lee A. Bulla The University of Texas at Dallas
Yang Liu
Yang Liu University of Michigan–Ann Arbor

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