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Immunology

D-Index
69
Citations
27386
World Ranking
2467
National Ranking
1179

Overview

Tyler J. Curiel is affiliated with The University of Texas at San Antonio in the United States and has a significant research footprint in the fields of Medicine and Immunology and Microbiology. Their work covers notable subfields such as Oncology, Immunology, Molecular Biology, Surgery, and Radiology, Nuclear Medicine and Imaging.

Curiel's research primarily focuses on topics related to cancer and immune system interactions. These main topics include:

  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Bladder and Urothelial Cancer Treatments
  • Monoclonal and Polyclonal Antibodies Research
  • T-cell and B-cell Immunology

Their publication record spans multiple journals, with frequent contributions to venues such as:

  • The Journal of Immunology (19 publications)
  • Regular and Young Investigator Award Abstracts (11 publications)
  • Cancer Research (10 publications)
  • Journal for ImmunoTherapy of Cancer (6 publications)
  • Immunity (3 publications)

Some of Tyler J. Curiel's recent papers include:

  • "Programmed death ligand 1 signals in cancer cells," 2022, Nature reviews. Cancer
  • "Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion," 2021, Nature
  • "TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures," 2022, Immunity
  • "Resident memory CD8+ T cells in regional lymph nodes mediate immunity to metastatic melanoma," 2021, Immunity
  • "Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells," 2022, Cancer Cell

Curiel collaborates regularly with a number of researchers, including:

  • Harshita B. Gupta (26 coauthored papers)
  • Yilun Deng (25 coauthored papers)
  • Álvaro Padrón (23 coauthored papers)
  • Anand Kornepati (22 coauthored papers)
  • Ryan M. Reyes (18 coauthored papers)

Best Publications

  • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival.

    Tyler J Curiel;George Coukos;Linhua Zou;Xavier Alvarez

  • Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity.

    Tyler J Curiel;Shuang Wei;Haidong Dong;Xavier Alvarez

  • Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes.

    T. H. Finkel;G. Tudor-Williams;N. K. Banda;M. F. Cotton

  • B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

    Ilona Kryczek;Ilona Kryczek;Linhua Zou;Linhua Zou;Paulo Rodriguez;Gefeng Zhu

  • Safety and Efficacy of Durvalumab (MEDI4736), an Anti–Programmed Cell Death Ligand-1 Immune Checkpoint Inhibitor, in Patients With Advanced Urothelial Bladder Cancer

    Christophe Massard;Michael S. Gordon;Sunil Sharma;Saeed Rafii

  • Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells.

    Weiping Zou;Weiping Zou;Véronique Machelon;Aurore Coulomb-L'Hermin;Jozef Borvak

  • Tregs and rethinking cancer immunotherapy

    Tyler J. Curiel

  • Interventions to Slow Aging in Humans: Are We Ready?

    Valter D. Longo;Adam Antebi;Andrzej Bartke;Nir Barzilai

  • CXCL12 and Vascular Endothelial Growth Factor Synergistically Induce Neoangiogenesis in Human Ovarian Cancers

    Ilona Kryczek;Andrzej Lange;Peter Mottram;Xavier Alvarez

  • Transplantation of enriched CD34-positive autologous marrow into breast cancer patients following high-dose chemotherapy: influence of CD34-positive peripheral-blood progenitors and growth factors on engraftment.

    E J Shpall;R B Jones;S I Bearman;W A Franklin

  • Bone marrow is a reservoir for CD4+CD25+ regulatory T cells that traffic through CXCL12/CXCR4 signals.

    Linhua Zou;Brian Barnett;Hana Safah;Vincent F. LaRussa

  • Programmed death ligand 1 signals in cancer cells

    Unknown

  • CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression

    Dachuan Jin;Jie Fan;Long Wang;Linda F. Thompson

  • Plasmacytoid Dendritic Cells Induce CD8+ Regulatory T Cells In Human Ovarian Carcinoma

    Shuang Wei;Ilona Kryczek;Ilona Kryczek;Linhua Zou;Ben Daniel

  • Cross-Talk in the Innate Immune System: Neutrophils Instruct Recruitment and Activation of Dendritic Cells during Microbial Infection

    Soumaya Bennouna;Susan K. Bliss;Tyler J. Curiel;Eric Y. Denkers

  • Tumor-intrinsic PD-L1 signals regulate cell growth, pathogenesis and autophagy in ovarian cancer and melanoma

    Curtis A Clark;Harshita Gupta;Gangadhara R. Sareddy;Srilakshmi Pandeswara

  • Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion.

    Xiujie Sun;Bogang Wu;Huai-Chin Chiang;Hui Deng

  • Combined autophagy and HDAC inhibition: a phase I safety, tolerability, pharmacokinetic, and pharmacodynamic analysis of hydroxychloroquine in combination with the HDAC inhibitor vorinostat in patients with advanced solid tumors.

    Devalingam Mahalingam;Monica Mita;John Sarantopoulos;Leslie Wood

  • Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer

    Tyler J. Curiel;Pui Cheng;Peter Mottram;Xavier Alvarez

  • Regulatory T cells and treatment of cancer

    Tyler J Curiel

  • Regulatory T Cells in Ovarian Cancer: Biology and Therapeutic Potential

    Brian Barnett;Ilona Kryczek;Pui Cheng;Weiping Zou

  • Toxoplasma gondii-Infected Cells Are Resistant to Multiple Inducers of Apoptosis

    Paul B. Nash;Matthew B. Purner;Ronald P. Leon;Penelope Clarke

Frequent Co-Authors

Weiping Zou
Weiping Zou University of Michigan–Ann Arbor
Yang Liu
Yang Liu University of Michigan–Ann Arbor
Ratna K. Vadlamudi
Ratna K. Vadlamudi The University of Texas at Austin
David T. Curiel
David T. Curiel Washington University in St. Louis
Ilona Kryczek
Ilona Kryczek University of Michigan–Ann Arbor
George Coukos
George Coukos Cornell University
Paul Hasty
Paul Hasty The University of Texas Health Science Center at San Antonio
Jose R. Conejo-Garcia
Jose R. Conejo-Garcia Duke University
Robert T. Schooley
Robert T. Schooley University of California, San Diego
Martin A. Javors
Martin A. Javors The University of Texas Health Science Center at San Antonio

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