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Hequan Yao

D-Index & Metrics

Chemistry

D-Index
50
Citations
8154
World Ranking
14477
National Ranking
2249

Hequan Yao publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Hequan Yao sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 262 publications — 53rd percentile

53% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Hequan Yao D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hequan Yao sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 50 D-Index — 21st percentile

21% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Hequan Yao is affiliated with China Pharmaceutical University in China and primarily works in the field of Chemistry. Their research focuses heavily on Organic Chemistry, with additional contributions in Molecular Biology, Materials Chemistry, Pharmacology, and Inorganic Chemistry.

The main topics of Hequan Yao's work include catalytic C-H functionalization methods, asymmetric synthesis and catalysis, asymmetric hydrogenation and catalysis, computational drug discovery methods, crystallization and solubility studies, X-ray diffraction in crystallography, and catalytic alkyne reactions.

Frequent venues for their research publications are:

  • Organic Letters
  • The Cambridge Structural Database
  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • Nature Communications

Key recent papers authored under Hequan Yao's name include:

  • Ligand-Controlled, Palladium-Catalyzed Asymmetric [4+4] and [2+4] Cycloadditions, 2021, Organic Letters
  • Constructing chiral bicyclo[3.2.1]octanes via palladium-catalyzed asymmetric tandem Heck/carbonylation desymmetrization of cyclopentenes, 2020, Nature Communications
  • Palladium-Catalyzed Asymmetric Sequential Hydroamination of 1,3-Enynes: Enantioselective Syntheses of Chiral Imidazolidinones, 2022, Journal of the American Chemical Society
  • Chemical space exploration based on recurrent neural networks: applications in discovering kinase inhibitors, 2020, Journal of Cheminformatics
  • Identification of a Potent Oridonin Analogue for Treatment of Triple-Negative Breast Cancer, 2020, Journal of Medicinal Chemistry

Hequan Yao collaborates regularly with several researchers, including:

  • Aijun Lin
  • Qiuyu Li
  • Xuanyi Li
  • Kejiang Lin
  • Shang Gao

Their research outputs demonstrate a focus on several specialized areas within organic and medicinal chemistry and employ advanced catalytic processes. The integration of computational drug discovery approaches also marks a multidisciplinary aspect of their work.

Best Publications

  • Fluorescence imaging in vivo: recent advances.

    Jianghong Rao;Anca Dragulescu-Andrasi;Hequan Yao

  • Quantum Dot/Bioluminescence Resonance Energy Transfer Based Highly Sensitive Detection of Proteases†

    Hequan Yao;Yan Zhang;Yan Zhang;Fei Xiao;Zuyong Xia

  • HaloTag protein-mediated site-specific conjugation of bioluminescent proteins to quantum dots.

    Yan Zhang;Min-kyung So;Andreas M. Loening;Hequan Yao

  • Imaging tuberculosis with endogenous β-lactamase reporter enzyme fluorescence in live mice

    Ying Kong;Hequan Yao;Hongjun Ren;Selvakumar Subbian;Selvakumar Subbian

  • Organocatalyzed Asymmetric 1,6-Conjugate Addition of para-Quinone Methides with Dicyanoolefins.

    Xuanyi Li;Xiuyan Xu;Weiwei Wei;Aijun Lin

  • Bifunctional Organo/Metal Cooperatively Catalyzed [3 + 2] Annulation of para-Quinone Methides with Vinylcyclopropanes: Approach to Spiro[4.5]deca-6,9-diene-8-ones.

    Zhenbo Yuan;Weiwei Wei;Aijun Lin;Hequan Yao

  • 1,6-Conjugated Addition-Mediated [2+1] Annulation: Approach to Spiro[2.5]octa-4,7-dien-6-one.

    Zhenbo Yuan;Xinxin Fang;Xuanyi Li;Jie Wu

  • Insights into drug discovery from natural products through structural modification.

    Jichao Chen;Wenlong Li;Hequan Yao;Jinyi Xu

  • Efficient Construction of Fused Indolines with a 2-Quaternary Center via an Intramolecular Heck Reaction with a Low Catalyst Loading

    Lei Zhao;Ziyuan Li;Lin Chang;Jinyi Xu

  • Synthesis of spiro[2.5]octa-4,7-dien-6-one with consecutive quaternary centers via 1,6-conjugate addition induced dearomatization of para-quinone methides

    Kuo Gai;Xinxin Fang;Xuanyi Li;Jinyi Xu

  • Controllable Rh(III)-Catalyzed Annulation between Salicylaldehydes and Diazo Compounds: Divergent Synthesis of Chromones and Benzofurans.

    Peng Sun;Shang Gao;Chi Yang;Songjin Guo

  • Rh(III)-Catalyzed Redox-Neutral Annulation of Primary Benzamides with Diazo Compounds: Approach to Isoquinolinones

    Youzhi Wu;Peng Sun;Kaifan Zhang;Tie Yang

  • 1,6‐Addition Arylation of para‐Quinone Methides: An Approach to Unsymmetrical Triarylmethanes

    Shang Gao;Xiuyan Xu;Zhenbo Yuan;Haipin Zhou

  • A Bioluminogenic Substrate for In Vivo Imaging of β‐Lactamase Activity

    Hequan Yao;Min-kyung So;Jianghong Rao

  • Discovery of Novel Quinoline–Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity

    Wenlong Li;Feijie Xu;Wen Shuai;Honghao Sun

  • Solvent-Controlled Switchable C–H Alkenylation of 4-Aryl-1H-pyrrole-3-carboxylates: Application to the Total Synthesis of (±)-Rhazinilam

    Youla Su;Haipin Zhou;Jiaxuan Chen;Jinyi Xu

  • 1,6-Conjugated addition-mediated [4 + 1] annulation: an approach to 2,3-dihydrobenzofurans

    Lina Liu;Zhenbo Yuan;Rui Pan;Yuye Zeng

  • [3 + 3] Cycloaddition of in Situ Formed Azaoxyallyl Cations with 2-Alkenylindoles: An Approach to Tetrahydro-β-carbolinones

    Kaifan Zhang;Xiaoying Xu;Jiuan Zheng;Hequan Yao

  • Discovery of novel hybrids of diaryl-1,2,4-triazoles and caffeic acid as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase for cancer therapy.

    Hao Cai;Xiaojing Huang;Shengtao Xu;Hao Shen

  • Synthesis and biological evaluation of ticagrelor derivatives as novel antiplatelet agents

    Hao Zhang;Jun Liu;Luyong Zhang;Lingyi Kong

  • A Novel Potent Anticancer Compound Optimized from a Natural Oridonin Scaffold Induces Apoptosis and Cell Cycle Arrest through the Mitochondrial Pathway

    Shengtao Xu;Hong Yao;Shanshan Luo;Yun-Kai Zhang

  • Multiple Roles of the Pyrimidyl Group in the Rhodium-Catalyzed Regioselective Synthesis and Functionalization of Indole-3-carboxylic Acid Esters

    Hui Jiang;Shang Gao;Jinyi Xu;Xiaoming Wu

  • Multifunctional tacrine-flavonoid hybrids with cholinergic, β-amyloid-reducing, and metal chelating properties for the treatment of Alzheimer's disease.

    Su-Yi Li;Xiao-Bing Wang;Sai-Sai Xie;Neng Jiang

  • Cascade Radical 1,6-Addition/Cyclization of para-Quinone Methides: Leading to Spiro[4.5]deca-6,9-dien-8-ones.

    Rui Pan;Lingyin Hu;Chunhua Han;Aijun Lin

  • [3 + 2] Cycloaddition Reaction of in Situ Formed Azaoxyallyl Cations with Aldehydes: An Approach to Oxazolidin-4-ones

    Kaifan Zhang;Chi Yang;Hequan Yao;Aijun Lin

Frequent Co-Authors

Jinyi Xu
Jinyi Xu China Pharmaceutical University
Ling-Yi Kong
Ling-Yi Kong China Pharmaceutical University
Jianghong Rao
Jianghong Rao Stanford University
Zhe-Sheng Chen
Zhe-Sheng Chen St. John's University
Wen-Cai Ye
Wen-Cai Ye Jinan University
Osamu Muraoka
Osamu Muraoka Kindai University
Qinglong Guo
Qinglong Guo China Pharmaceutical University
Jun O. Liu
Jun O. Liu Johns Hopkins University School of Medicine
James C. Sacchettini
James C. Sacchettini Texas A&M University
Sanjiv S. Gambhir
Sanjiv S. Gambhir Stanford University

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