Apoptosis, Gambogic acid, Cancer research, Wogonin and Cell biology are his primary areas of study. His Apoptosis study is concerned with the larger field of Biochemistry. The concepts of his Gambogic acid study are interwoven with issues in Garcinia, Cyclin-dependent kinase 1, Molecular biology, Growth inhibition and Phosphorylation.
His Molecular biology study integrates concerns from other disciplines, such as Angiogenesis, Telomerase, Telomerase reverse transcriptase, MTT assay and DNA fragmentation. His Cancer research research is multidisciplinary, incorporating elements of Cell growth, Immunology, Matrix metalloproteinase, Metastasis and MAPK/ERK pathway. His Cell biology study combines topics in areas such as Cell cycle checkpoint, Integrin, Ubiquitin and Immunoprecipitation.
Qidong You mainly investigates Biochemistry, Stereochemistry, Pharmacology, Combinatorial chemistry and Cancer research. His work in In vitro, Apoptosis, Gambogic acid, Enzyme and Protein–protein interaction is related to Biochemistry. His Apoptosis research incorporates elements of Molecular biology and Cell biology.
Qidong You undertakes multidisciplinary investigations into Pharmacology and Wogonin in his work. His research in Combinatorial chemistry intersects with topics in Pharmacophore, Virtual screening and Organic chemistry. His Cancer research research is multidisciplinary, incorporating perspectives in Cancer cell and Signal transduction, Kinase, MAPK/ERK pathway.
His scientific interests lie mostly in Pharmacology, Cell biology, Protein–protein interaction, Cancer research and Small molecule. His Pharmacology research incorporates themes from Oxidative stress, IC50, Rheumatoid arthritis and Drug discovery. His Cell biology research includes themes of Heat shock protein, CDC37 and Hsp90.
His Protein–protein interaction study is concerned with the field of Biochemistry as a whole. The study of Biochemistry is intertwined with the study of Reagent in a number of ways. His Cancer research research is multidisciplinary, incorporating perspectives in Cancer, Cancer therapy, Apoptosis, Tamoxifen and Signal transduction.
His main research concerns Cancer research, Protein–protein interaction, Pharmacology, Cancer and Hsp90. He combines subjects such as Docking, Leukemia, HL60, Tamoxifen and PI3K/AKT/mTOR pathway with his study of Cancer research. Qidong You is investigating Biochemistry and Cell biology as part of his examination of Protein–protein interaction.
His Biochemistry research incorporates elements of Metal and Metal binding. He has included themes like Oxidative stress, Structure–activity relationship, Antioxidant and MPTP in his Pharmacology study. Qidong You interconnects Cell cycle checkpoint, Computational biology, Chaperone and Cell growth in the investigation of issues within Hsp90.
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The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update.
Meng-Chen Lu;Jian-Ai Ji;Zheng-Yu Jiang;Qi-Dong You.
Medicinal Research Reviews (2016)
Endostar, a novel recombinant human endostatin, exerts antiangiogenic effect via blocking VEGF-induced tyrosine phosphorylation of KDR/Flk-1 of endothelial cells.
Yun Ling;Yong Yang;Na Lu;Qi-dong You.
Biochemical and Biophysical Research Communications (2007)
Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cells.
Jun Yu;Qing-Long Guo;Qi-Dong You;Li Zhao.
ISOLATION AND CHARACTERIZATION OF CANCER STEM LIKE CELLS IN HUMAN GLIOBLASTOMA CELL LINES
Lei Qiang;Yong Yang;Yan-Jun Ma;Fei-Hong Chen.
Cancer Letters (2009)
Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cells.
Zhao-Qiu Wu;Qing-Long Guo;Qi-Dong You;Li Zhao.
Biological & Pharmaceutical Bulletin (2004)
Anti-hepatitis B virus activity of wogonin in vitro and in vivo.
Qinglong Guo;Li Zhao;Qidong You;Yong Yang.
Antiviral Research (2007)
Flavonoid baicalein suppresses adhesion, migration and invasion of MDA-MB-231 human breast cancer cells
Ling Wang;Yun Ling;Yan Chen;Cheng-Ling Li.
Cancer Letters (2010)
Chiral Drugs: Chemistry and Biological Action
Guo-Qiang Lin;Qi-Dong You;Jie-Fei Cheng.
Discovery of potent Keap1-Nrf2 protein-protein interaction inhibitor based on molecular binding determinants analysis.
Zheng-Yu Jiang;Meng-Chen Lu;Li Li Xu;Ting-Ting Yang.
Journal of Medicinal Chemistry (2014)
Differential apoptotic induction of gambogic acid, a novel anticancer natural product, on hepatoma cells and normal hepatocytes.
Yong Yang;Lan Yang;Qi-Dong You;Fei-Fei Nie.
Cancer Letters (2007)
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