Qidong You

Overview

Best Publications

• The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update.

  Meng-Chen Lu;Jian-Ai Ji;Zheng-Yu Jiang;Qi-Dong You

  783
  Citations

• HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway

  Qiang L;Wu T;Zhang Hw;Lu N

  336
  Citations

• Endostar, a novel recombinant human endostatin, exerts antiangiogenic effect via blocking VEGF-induced tyrosine phosphorylation of KDR/Flk-1 of endothelial cells.

  Yun Ling;Yong Yang;Na Lu;Qi-dong You

  301
  Citations

• Chiral Drugs: Chemistry and Biological Action

  Guo-Qiang Lin;Qi-Dong You;Jie-Fei Cheng

  270
  Citations

• Discovery of a Keap1-dependent peptide PROTAC to knockdown Tau by ubiquitination-proteasome degradation pathway.

  Mengchen Lu;Tian Liu;Qiong Jiao;Jianai Ji

  265
  Citations

• ISOLATION AND CHARACTERIZATION OF CANCER STEM LIKE CELLS IN HUMAN GLIOBLASTOMA CELL LINES

  Lei Qiang;Yong Yang;Yan-Jun Ma;Fei-Hong Chen

  253
  Citations

• Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cells.

  Jun Yu;Qing-Long Guo;Qi-Dong You;Li Zhao

  239
  Citations

• Discovery of potent Keap1-Nrf2 protein-protein interaction inhibitor based on molecular binding determinants analysis.

  Zheng-Yu Jiang;Meng-Chen Lu;Li Li Xu;Ting-Ting Yang

  235
  Citations

• Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cells.

  Zhao-Qiu Wu;Qing-Long Guo;Qi-Dong You;Li Zhao

  232
  Citations

• Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6.

  Arduino A. Mangoni;Catherine Guillou;Jean Jacques Vanden Eynde;Christopher Hulme

  230
  Citations

• Anti-hepatitis B virus activity of wogonin in vitro and in vivo.

  Qinglong Guo;Li Zhao;Qidong You;Yong Yang

  228
  Citations

• Flavonoid baicalein suppresses adhesion, migration and invasion of MDA-MB-231 human breast cancer cells

  Ling Wang;Yun Ling;Yan Chen;Cheng-Ling Li

  228
  Citations

• Differential apoptotic induction of gambogic acid, a novel anticancer natural product, on hepatoma cells and normal hepatocytes.

  Yong Yang;Lan Yang;Qi-Dong You;Fei-Fei Nie

  191
  Citations

• Heat Shock Protein 90 Inhibitors: An Update on Achievements, Challenges, and Future Directions.

  Li Li;Lei Wang;Qi-Dong You;Xiao-Li Xu

  170
  Citations

• Inhibition of human telomerase reverse transcriptase gene expression by gambogic acid in human hepatoma SMMC-7721 cells

  Qing-Long Guo;Sen-Sen Lin;Qi-Dong You;Hong-Yan Gu

  159
  Citations

• Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2.

  Xiaoyun Lu;Xiaobo Liu;Baojie Wan;Scott G. Franzblau

  135
  Citations

• Discovery and Development of Kelch-like ECH-Associated Protein 1. Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein–Protein Interaction Inhibitors: Achievements, Challenges, and Future Directions

  Zheng-Yu Jiang;Meng-Chen Lu;Qi-Dong You

  134
  Citations

• Gambogic acid inhibits angiogenesis through suppressing vascular endothelial growth factor-induced tyrosine phosphorylation of KDR/Flk-1.

  Na Lu;Yong Yang;Qi-Dong You;Yun Ling

  131
  Citations

• An inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic cells and alleviates experimental colitis.

  Meng-Chen Lu;Jian-Ai Ji;Yong-Lin Jiang;Zhi-Yun Chen

  131
  Citations

• Drug resistance associates with activation of Nrf2 in MCF-7/DOX cells, and wogonin reverses it by down-regulating Nrf2-mediated cellular defense response.

  Yan Zhong;Fengyi Zhang;Zhongying Sun;Wei Zhou

  130
  Citations