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Seisuke Hattori

Seisuke Hattori

D-Index & Metrics

Biology and Biochemistry

D-Index
45
Citations
9928
World Ranking
19066
National Ranking
1376

Overview

Seisuke Hattori is affiliated with Kitasato University in Japan and works primarily in the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine. Their research spans multiple subfields including Molecular Biology, Cell Biology, Pulmonary and Respiratory Medicine, Virology, and Public Health, Environmental and Occupational Health. The scientist's work addresses several key topics such as PI3K/AKT/mTOR signaling in cancer, Polyamine Metabolism and Applications, Occupational and environmental lung diseases, HIV Research and Treatment, Lipid Membrane Structure and Behavior, RNA Interference and Gene Delivery, and Acute Lymphoblastic Leukemia research.

Seisuke Hattori has contributed scholarly articles to a variety of publication venues including:

  • Molecular Cancer Research
  • Viruses
  • Journal of Chromatography B
  • International Journal of Pharmaceutical Sciences Research
  • FEBS Letters

Recent papers authored or co-authored by Hattori include:

  • Silencing of SmgGDS, a Novel mTORC1 Inducer That Binds to RHEBs, Inhibits Malignant Mesothelioma Cell Proliferation (2021, Molecular Cancer Research)
  • A Proteomic Analysis of Detergent-Resistant Membranes in HIV Virological Synapse: The Involvement of Vimentin in CD4 Polarization (2023, Viruses)
  • Measurement of the intracellular active metabolites of thiopurine drugs to evaluate the enzymatic activity of nudix hydrolase 15 in human blood samples (2024, Journal of Chromatography B)
  • Discovery of Oosporein as a New Inhibitor of Influenza Virus Cap-snatching Activity (2020, International Journal of Pharmaceutical Sciences Research)
  • Septin2 regulates ARHGAP25-mediated suppression of lamellipodia formation and cell spreading (2025, FEBS Letters)

Frequent collaborators in Hattori's research include:

  • Yoshio Shibagaki
  • Emi Mishiro-Sato
  • Mitsuru Okuwaki
  • Tatsuhiro Sato
  • Satomi Mukai

Hattori's contributions cover a spectrum of molecular and cellular biology topics focused on cancer signaling pathways and viral mechanisms, among others. This research is often situated at the intersection of basic biochemical processes and applied medical science, particularly within pulmonary and infectious disease contexts.

Best Publications

  • Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA.

    Motoharu Seiki;Seisuke Hattori;Yoko Hirayama;Mitsuaki Yoshida

  • JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins

    Fuminori Tsuruta;Jun Sunayama;Yasunori Mori;Seisuke Hattori

  • Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G.

    Takaya Gotoh;Seisuke Hattori;Shun Nakamura;Hitoshi Kitayama

  • C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.

    Shinya Tanaka;Takashi Morishita;Yuko Hashimoto;Seisuke Hattori

  • Human adult T-cell leukemia virus: molecular cloning of the provirus DNA and the unique terminal structure

    Motoharu Seiki;Seisuke Hattori;Mistuaki Yoshida

  • The G protein Gα12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain

    Yun Jiang;Wei Ma;Yong Wan;Tohru Kozasa

  • CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells.

    Michiyuki Matsuda;Yuko Hashimoto;Kenkoh Muroya;Hideki Hasegawa

  • Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport

    Hidetaka Kosako;Hidetaka Kosako;Nozomi Yamaguchi;Chizuru Aranami;Masato Ushiyama;Masato Ushiyama

  • Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3.

    Yusuke Ohba;Naoki Mochizuki;Shigeko Yamashita;Andrew M. Chan

  • Induction of neurite outgrowth by MAP kinase in PC12 cells.

    M Fukuda;Y Gotoh;T Tachibana;K Dell

  • Epidermal growth factor-receptor mutant lacking the autophosphorylation sites induces phosphorylation of Shc protein and Shc-Grb2/ASH association and retains mitogenic activity.

    N Gotoh;A Tojo;K Muroya;Y Hashimoto

  • Identification of gag and env gene products of human T-cell leukemia virus (HTLV)

    Seisuke Hattori;Tetsuyuki Kiyokawa;Ken-Ichi Imagawa;Fumio Shimizu

  • A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions.

    M. Maekawa;Shaowei Li;A. Iwamatsu;T. Morishita

  • Activation of R-Ras by Ras-Guanine Nucleotide-releasing Factor

    Takaya Gotoh;Yuko Niino;Masaaki Tokuda;Osamu Hatase

  • Both the SH2 and SH3 domains of human CRK protein are required for neuronal differentiation of PC12 cells.

    Shinya Tanaka;Seisuke Hattori;Takeshi Kurata;Kazuo Nagashima

  • Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras.

    Shunji Yunoue;Shunji Yunoue;Hiroshi Tokuo;Kohji Fukunaga;Liping Feng

  • Enhancement of guanine-nucleotide exchange activity of C3G for Rap1 by the expression of Crk, CrkL, and Grb2

    Tamotsu Ichiba;Yasunobu Kuraishi;Osamu Sakai;Satoshi Nagata

  • Neph1, a component of the kidney slit diaphragm, is tyrosine-phosphorylated by the Src family tyrosine kinase and modulates intracellular signaling by binding to Grb2.

    Yutaka Harita;Hidetake Kurihara;Hidetaka Kosako;Tohru Tezuka

  • Mutations of the ras gene product p21 that abolish guanine nucleotide binding.

    David J. Clanton;Seisuke Hattori;Thomas Y. Shih

  • Involvement of Prolonged Ras Activation in Thrombopoietin-Induced Megakaryocytic Differentiation of a Human Factor-Dependent Hematopoietic Cell Line

    Itaru Matsumura;Koichi Nakajima;Hiroshi Wakao;Seisuke Hattori

Frequent Co-Authors

Hidetaka Kosako
Hidetaka Kosako University of Tokushima
Michiyuki Matsuda
Michiyuki Matsuda Kyoto University
Motoharu Seiki
Motoharu Seiki University of Tokyo
Mitsuaki Yoshida
Mitsuaki Yoshida University of Tokyo
Yukiko Gotoh
Yukiko Gotoh University of Tokyo
Takeshi Kurata
Takeshi Kurata Juntendo University
Akihiro Iwamatsu
Akihiro Iwamatsu Osaka University
Yoshinori Murakami
Yoshinori Murakami University of Tokyo

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