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Genetics

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Medicine

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Overview

Patrick Concannon is a researcher affiliated with the University of Florida in the United States. Their research primarily focuses on genetics, immunology, molecular biology, and endocrinology, with a significant emphasis on diabetes and associated disorders.

Their work spans the fields of biochemistry, genetics, molecular biology, and medicine, with substantial contributions in several subfields including genetics, immunology, molecular biology, surgery, and endocrinology, diabetes, and metabolism.

Concannon's main research topics include:

  • Diabetes and associated disorders
  • Pancreatic function and diabetes
  • BRCA gene mutations in cancer
  • Immune cell function and interaction
  • Diabetes management and research
  • T-cell and B-cell immunology
  • DNA repair mechanisms

Their recent publications reflect the focus on type 1 diabetes, immune response, and genetic factors related to cancer risk. Notable papers include:

  • "Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes," 2021, Nature Genetics
  • "Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "Radiation Treatment, ATM, BRCA1/2, and CHEK2*1100delC Pathogenic Variants and Risk of Contralateral Breast Cancer," 2020, JNCI Journal of the National Cancer Institute
  • "Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes," 2021, Genome Biology
  • "Human immune phenotyping reveals accelerated aging in type 1 diabetes," 2023, JCI Insight

Patrick Concannon has collaborated frequently with several researchers including Suna Önengüt-Gümüşcü, Jeremy R. B. Newman, Mark A. Atkinson, Stephen S. Rich, and Jonine L. Bernstein. These collaborations appear across multiple studies related to their fields of interest.

Their work has been published in a range of scholarly venues with repeated contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Diabetes
  • Zenodo (CERN European Organization for Nuclear Research)
  • JNCI Journal of the National Cancer Institute
  • Genes and Immunity

Best Publications

  • Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

    Jeffrey C Barrett;David G Clayton;Patrick Concannon;Beena Akolkar

  • Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

    Y Horikawa;N Oda;N J Cox;X Li;X Li

  • Gut microbiomes of Malawian twin pairs discordant for kwashiorkor

    Michelle I. Smith;Tanya Yatsunenko;Mark J. Manary;Mark J. Manary;Mark J. Manary;Indi Trehan;Indi Trehan

  • Nibrin, a Novel DNA Double-Strand Break Repair Protein, Is Mutated in Nijmegen Breakage Syndrome

    Raymonda Varon;Christine Vissinga;Matthias Platzer;Karen M Cerosaletti

  • Breast-Cancer Risk in Families with Mutations in PALB2

    A. C. Antoniou;S. Casadei;T. Heikkinen;D. Barrowdale

  • HLA DR-DQ Haplotypes and Genotypes and Type 1 Diabetes Risk: Analysis of the Type 1 Diabetes Genetics Consortium Families

    Henry Erlich;Ana Maria Valdes;Janelle Noble;Joyce A. Carlson

  • Localization of an ataxia-telangiectasia gene to chromosome 11q22–23

    Richard A. Gatti;Izzet Berkel;Elena Boder;Gary Braedt

  • A genome–wide search for human non–insulin–dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2

    Craig L Hanis;Eric Boerwinkle;R. Chakraborty;D. L. Ellsworth

  • High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

    Steve Eyre;John Bowes;John Bowes;Dorothée Diogo;Dorothée Diogo;Annette Lee

  • Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.

    Suna Onengut-Gumuscu;Wei-Min Chen;Oliver Burren;Nick J Cooper

  • Imputing Amino Acid Polymorphisms in Human Leukocyte Antigens

    Xiaoming Jia;Buhm Han;Buhm Han;Suna Onengut-Gumuscu;Wei Min Chen

  • Genetics of Type 1A Diabetes

    Patrick Concannon;Stephen S. Rich;Gerald T. Nepom

  • ATM-dependent phosphorylation of nibrin in response to radiation exposure

    Magtouf Gatei;David Young;Karen M. Cerosaletti;Ami Desai-Mehta

  • DNA Ligase IV Mutations Identified in Patients Exhibiting Developmental Delay and Immunodeficiency

    Mark O'Driscoll;Karen M. Cerosaletti;Pierre M. Girard;Yan Dai

  • Structure, organization and polymorphism of murine and human T-cell receptor alpha and beta chain gene families.

    Richard K. Wilson;Eric Lai;Patrick Concannon;Richard K. Barth

  • Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans.

    Nancy J. Cox;Mike Frigge;Dan L. Nicolae;Dan L. Nicolae;Patrick Concannon

  • Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis

    Anne Hinks;Anne Hinks;Joanna E. Cobb;Joanna E. Cobb;Miranda C. Marion;Sampath Prahalad

  • ATR‐dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling

    Thomas Stiff;Sarah A Walker;Karen Cerosaletti;Aaron A Goodarzi

  • Genetic Variation in PTPN22 Corresponds to Altered Function of T and B Lymphocytes

    Mary Rieck;Adrian Arechiga;Suna Onengut-Gumuscu;Carla Greenbaum

  • Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

    Suna Onengut-Gumuscu;Wei-Min Chen;Oliver Burren;Emily Farber

Frequent Co-Authors

Richard A. Gatti
Richard A. Gatti University of California, Los Angeles
Stephen S. Rich
Stephen S. Rich University of Virginia
Charles F. Lynch
Charles F. Lynch University of Iowa
John A. Todd
John A. Todd University of Oxford
Robert W. Haile
Robert W. Haile Stanford University
Flemming Pociot
Flemming Pociot Steno Diabetes Center
Henry A. Erlich
Henry A. Erlich UCSF Benioff Children's Hospital
Grant Morahan
Grant Morahan Harry Perkins Institute of Medical Research
Julia A. Knight
Julia A. Knight Lunenfeld-Tanenbaum Research Institute
Esther M. John
Esther M. John Stanford University

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