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D-Index & Metrics

Biology and Biochemistry

D-Index
40
Citations
6451
World Ranking
19590
National Ranking
7980

Overview

Amit Gaggar is affiliated with the University of Alabama at Birmingham in the United States. Their research primarily falls within the field of Medicine, with a strong focus on Pulmonary and Respiratory Medicine, Molecular Biology, Immunology, Epidemiology, and Infectious Diseases. This interdisciplinary approach supports investigations into complex respiratory conditions and related biological mechanisms.

The scientist's main research topics cover a range of respiratory health issues and disease processes, including:

  • Neonatal Respiratory Health Research
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Cystic Fibrosis Research Advances
  • Extracellular vesicles in disease
  • Respiratory Support and Mechanisms
  • COVID-19 Clinical Research Studies
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Key recent publications demonstrate continued involvement in investigating respiratory diseases, infection mechanisms, and immune cell function. Some notable papers include:

  • COVID-19 bacteremic co-infection is a major risk factor for mortality, ICU admission, and mechanical ventilation, 2023, Critical Care
  • Transcriptional firing represses bactericidal activity in cystic fibrosis airway neutrophils, 2021, Cell Reports Medicine
  • Spatial Transcriptomics Resolve an Emphysema-Specific Lymphoid Follicle B Cell Signature in Chronic Obstructive Pulmonary Disease, 2023, American Journal of Respiratory and Critical Care Medicine
  • Circulating SARS-CoV-2+ megakaryocytes are associated with severe viral infection in COVID-19, 2023, Blood Advances
  • An in vivo model for extracellular vesicle-induced emphysema, 2022, JCI Insight

The scientist frequently publishes in several specialized journals, with multiple contributions to:

  • American Journal of Respiratory and Critical Care Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Cystic Fibrosis
  • JCI Insight
  • The Journal of Heart and Lung Transplantation

Amit Gaggar collaborates regularly with a core group of coauthors, including:

  • Camilla Margaroli
  • J. Edwin Blalock
  • Kristopher R. Genschmer
  • Rakesh P. Patel
  • Matthew C. Madison

Best Publications

  • A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation.

    Amit Gaggar;Patricia L. Jackson;Brett D. Noerager;Philip J. O’Reilly

  • The ups and downs of peer review.

    Dale J. Benos;Edlira Bashari;Jose M. Chaves;Amit Gaggar

  • Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung.

    Kristopher R. Genschmer;Derek W. Russell;Charitharth Lal;Tomasz Szul

  • Innate immunity in cystic fibrosis lung disease

    D. Hartl;A. Gaggar;E. Bruscia;A. Hector

  • A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation

    Robert J. Snelgrove;Robert J. Snelgrove;Patricia L. Jackson;Matthew T. Hardison;Brett D. Noerager

  • Fibrosis: ultimate and proximate causes

    Victor J. Thannickal;Yong Zhou;Amit Gaggar;Steven R. Duncan

  • MMP generated matrikines.

    J. Michael Wells;J. Michael Wells;Amit Gaggar;J. Edwin Blalock

  • A Self-Propagating Matrix Metalloprotease-9 (MMP-9) Dependent Cycle of Chronic Neutrophilic Inflammation

    Xin Xin Xu;Patricia L. Jackson;Scott Tanner;Matthew T. Hardison

  • Matrix metalloprotease-9 dysregulation in lower airway secretions of cystic fibrosis patients

    Amit Gaggar;Yao Li;Nathaniel Weathington;Margaret Winkler

  • Protective effect of suppressing STAT3 activity in LPS-induced acute lung injury

    Jiping Zhao;Hao Yu;Yudong Liu;Sara A. Gibson

  • Potential Role of High-Mobility Group Box 1 in Cystic Fibrosis Airway Disease

    Steven M. Rowe;Patricia L. Jackson;Gang Liu;Mathew Hardison

  • The role of matrix metalloproteinases in cystic fibrosis lung disease.

    Amit Gaggar;Andreas Hector;Preston E. Bratcher;Marcus A. Mall

  • Inhibition of airway proteases in cystic fibrosis lung disease

    M. Griese;M. Kappler;A. Gaggar;D. Hartl

  • N-α-PGP and PGP, potential biomarkers and therapeutic targets for COPD

    Philip O'Reilly;Patricia L Jackson;Brett Noerager;Suzanne Parker

  • Matrix Metalloproteinase 9 Activity Enhances Host Susceptibility to Pulmonary Infection with Type A and B Strains of Francisella tularensis

    Meenakshi Malik;Chandra Shekhar Bakshi;Kathleen McCabe;Sally V. Catlett

  • Matrix Remodeling in Pulmonary Fibrosis and Emphysema

    Tejaswini Kulkarni;Philip O’Reilly;Veena B. Antony;Amit Gaggar;Amit Gaggar

  • TLR expression on neutrophils at the pulmonary site of infection: TLR1/TLR2-mediated up-regulation of TLR5 expression in cystic fibrosis lung disease

    Barbara Koller;Matthias Kappler;Phillip Latzin;Amit Gaggar

  • Human neutrophil elastase-mediated cleavage sites of MMP-9 and TIMP-1: implications to cystic fibrosis proteolytic dysfunction.

    Patricia L. Jackson;Xin Xu;Landon Wilson;Nathaniel M. Weathington

  • Extensive surgical and comprehensive postoperative medical management for cystic fibrosis chronic rhinosinusitis.

    Frank W. Virgin;Steven M. Rowe;Mary B. Wade;Amit Gaggar

  • A Self-Propagating Matrix Metalloprotease-9 (MMP-9) Dependent Cycle Of Chronic Neutrophilic Inflammation

    Amit Gaggar;Xin Xu;Patricia L. Jackson;Scott Tanner

Frequent Co-Authors

J. Edwin Blalock
J. Edwin Blalock University of Alabama at Birmingham
Mark T. Dransfield
Mark T. Dransfield University of Alabama at Birmingham
John P. Clancy
John P. Clancy Cystic Fibrosis Foundation
Steven M. Rowe
Steven M. Rowe University of Alabama at Birmingham
Namasivayam Ambalavanan
Namasivayam Ambalavanan University of Alabama at Birmingham
Gert Folkerts
Gert Folkerts Utrecht University
David D. Chaplin
David D. Chaplin University of Alabama at Birmingham
Frank A. Redegeld
Frank A. Redegeld Utrecht University
Jaroslaw W. Zmijewski
Jaroslaw W. Zmijewski University of Alabama at Birmingham
Dominik Hartl
Dominik Hartl Novartis (Switzerland)

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