World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
19790
World Ranking
5323
National Ranking
2525

Overview

J. Edwin Blalock is a researcher affiliated with the University of Alabama at Birmingham in the United States. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on Pulmonary and Respiratory Medicine and Molecular Biology as leading subfields.

The scientist's recent research has addressed topics such as Neonatal Respiratory Health Research, Extracellular Vesicles in Disease, and Chronic Obstructive Pulmonary Disease (COPD) Research. Additional research areas include Pulmonary Hypertension Research and Treatments, Respiratory Support and Mechanisms, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, and Connective Tissue Disorders Research.

J. Edwin Blalock's publication record demonstrates contributions across several notable venues in respiratory and molecular medicine. Frequent publication venues include:

  • JCI Insight
  • American Journal of Respiratory and Critical Care Medicine
  • Journal of Clinical Investigation
  • Annual Review of Physiology
  • Nature Communications

The following recent papers illustrate the range of their research contributions:

  • "Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD" (2020, Journal of Clinical Investigation)
  • "Extracellular Vesicles as Central Mediators of COPD Pathophysiology" (2021, Annual Review of Physiology)
  • "An in vivo model for extracellular vesicle-induced emphysema" (2022, JCI Insight)
  • "A lactobacilli-based inhaled live biotherapeutic product attenuates pulmonary neutrophilic inflammation" (2024, Nature Communications)
  • "A mechanism for matrikine regulation in acute inflammatory lung injury" (2021, JCI Insight)

Their collaborative work includes frequent coauthors such as:

  • Amit Gaggar
  • Kristopher R. Genschmer
  • Derek W. Russell
  • Camilla Margaroli
  • Matthew C. Madison

Overall, the body of work reflects a focus on understanding mechanisms underlying respiratory diseases, with a particular emphasis on inflammatory pathways and extracellular vesicles. The research spans both fundamental molecular insights and applied investigations relevant to pulmonary health and disease.

Best Publications

  • A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation.

    Nathaniel M Weathington;Anneke H van Houwelingen;Brett D Noerager;Patricia L Jackson

  • Interactions between the neuroendocrine and immune systems: common hormones and receptors.

    Douglas A. Weigent;J. Edwin Blalock

  • A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation.

    Amit Gaggar;Patricia L. Jackson;Brett D. Noerager;Philip J. O’Reilly

  • Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung.

    Kristopher R. Genschmer;Derek W. Russell;Charitharth Lal;Tomasz Szul

  • A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation

    Robert J. Snelgrove;Robert J. Snelgrove;Patricia L. Jackson;Matthew T. Hardison;Brett D. Noerager

  • Similarity between the corticotropin (ACTH) receptor and a peptide encoded by an RNA that is complementary to ACTH mRNA

    K L Bost;E M Smith;J E Blalock

  • Production of immunoreactive growth hormone by mononuclear leukocytes

    D A Weigent;J B Baxter;W E Wear;L R Smith

  • MMP generated matrikines.

    J. Michael Wells;J. Michael Wells;Amit Gaggar;J. Edwin Blalock

  • Estrogen modulates inflammatory mediator expression and neutrophil chemotaxis in injured arteries.

    Andrew P. Miller;Wenguang Feng;Dongqi Xing;Nathaniel M. Weathington

  • CFTR chloride channel regulation by an interdomain interaction.

    Anjaparavanda P. Naren;Estelle Cormet-Boyaka;Jian Fu;Matteo Villain

  • Conceptual development of the immune system as a sixth sense

    J. Edwin Blalock;Eric M. Smith

  • Cigarette Smoke Induces Systemic Defects in Cystic Fibrosis Transmembrane Conductance Regulator Function

    S. Vamsee Raju;Patricia L. Jackson;Clifford A. Courville;Carmel M. McNicholas

  • Matrix metalloproteinase-8 facilitates neutrophil migration through the corneal stromal matrix by collagen degradation and production of the chemotactic peptide Pro-Gly-Pro.

    Michelle Lin;Patricia Jackson;Angus M. Tester;Eugenia Diaconu

  • Collagen degradation and neutrophilic infiltration: a vicious circle in inflammatory bowel disease

    Pim J Koelink;Saskia A Overbeek;Saskia Braber;Mary E Morgan

  • Neuroendocrine peptide hormones and their receptors in the immune system. Production, processing and action.

    J.Edwin Blalock;Kenneth L. Bost;Eric M. Smith

  • Calcium influx factor is synthesized by yeast and mammalian cells depleted of organellar calcium stores.

    Peter Csutora;Zhengchang Su;Hak Yong Kim;Andrej Bugrim

  • Estrogen modulates TNF-α-induced inflammatory responses in rat aortic smooth muscle cells through estrogen receptor-β activation

    Dongqi Xing;Wenguang Feng;Andrew P. Miller;Nathaniel M. Weathington

  • Matrix metalloprotease-9 dysregulation in lower airway secretions of cystic fibrosis patients

    Amit Gaggar;Yao Li;Nathaniel Weathington;Margaret Winkler

  • Inhibition of self-binding antibodies (autobodies) by a VH-derived peptide.

    Chang-Yuil Kang;T. K. Brunck;T. Kieber-Emmons;J. E. Blalock

  • Potential Role of High-Mobility Group Box 1 in Cystic Fibrosis Airway Disease

    Steven M. Rowe;Patricia L. Jackson;Gang Liu;Mathew Hardison

Frequent Co-Authors

Amit Gaggar
Amit Gaggar University of Alabama at Birmingham
Kenneth L. Bost
Kenneth L. Bost University of North Carolina at Charlotte
Gert Folkerts
Gert Folkerts Utrecht University
Daniel J. J. Carr
Daniel J. J. Carr University of Oklahoma Health Sciences Center
Steven M. Rowe
Steven M. Rowe University of Alabama at Birmingham
Frans P. Nijkamp
Frans P. Nijkamp Utrecht University
Mark T. Dransfield
Mark T. Dransfield University of Alabama at Birmingham
John P. Clancy
John P. Clancy Cystic Fibrosis Foundation
John N. Whitaker
John N. Whitaker King's College London
Suzanne Oparil
Suzanne Oparil University of Alabama at Birmingham

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry can open doors to a variety of rewarding careers. As digital education evolves, students now have greater flexibility through online biology degree programs. These accelerated options offer a convenient pathway for those seeking a comprehensive foundation in the life sciences.

For individuals interested in healthcare, many choose to pursue online nursing programs to begin or advance their clinical careers. The nursing field remains in high demand, making flexible education options especially attractive.

Nutrition and wellness are also growing sectors. An online nutritionist degree provides a solid background for roles in healthcare, food science, and counseling.

Leadership and management roles are accessible for those who aspire to shape healthcare systems. Choosing cahme accreditation mha programs ensures your master’s in healthcare administration meets rigorous industry standards.

Whether you’re seeking a science-focused career or planning to lead in healthcare, online degrees offer the flexibility and specialization you need to succeed.

Best Scientists Citing J. Edwin Blalock

Trending Scientists

Recently Published Articles