World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
95
Citations
27962
World Ranking
10182
National Ranking
561

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Opioid

Christoph Stein focuses on Opioid, Endocrinology, Internal medicine, Inflammation and Opioid peptide. The study incorporates disciplines such as Morphine, Pharmacology and Nociception in addition to Opioid. Clinical trial and Pain ladder is closely connected to Anesthesia in his research, which is encompassed under the umbrella topic of Nociception.

His work deals with themes such as Sciatic nerve, Anatomy, Opioid receptor and Enkephalin, which intersect with Endocrinology. His Inflammation research focuses on subjects like Immune system, which are linked to Sensory nerve and Stimulation. His studies deal with areas such as Endorphins, beta-Endorphin and Endogenous opioid as well as Opioid peptide.

His most cited work include:

  • Advances in Neuropathic Pain: Diagnosis, Mechanisms, and Treatment Recommendations (1053 citations)
  • The Control of Pain in Peripheral Tissue by Opioids (604 citations)
  • Increased content and transport of substance P and calcitonin gene-related peptide in sensory nerves innervating inflamed tissue: evidence for a regulatory function of nerve growth factor in vivo. (558 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Opioid, Pharmacology, Opioid peptide, Receptor and Inflammation. Christoph Stein interconnects Morphine, Anesthesia, Analgesic and Endocrinology in the investigation of issues within Opioid. His biological study spans a wide range of topics, including Agonist and Nociception.

Internal medicine covers Christoph Stein research in Opioid peptide. As part of one scientific family, Christoph Stein deals mainly with the area of Receptor, narrowing it down to issues related to the Peripheral, and often Neuroscience. His work focuses on many connections between Inflammation and other disciplines, such as Cell adhesion molecule, that overlap with his field of interest in Extravasation.

He most often published in these fields:

  • Opioid (61.26%)
  • Pharmacology (33.77%)
  • Opioid peptide (35.43%)

What were the highlights of his more recent work (between 2014-2021)?

  • Opioid (61.26%)
  • Pharmacology (33.77%)
  • Receptor (33.77%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Opioid, Pharmacology, Receptor, Analgesic and Opioid receptor. His research in Opioid intersects with topics in Hyperalgesia, Sedation and Addiction. His Pharmacology research is multidisciplinary, incorporating perspectives in Agonist, Opioid analgesics and Nociception.

His Receptor study integrates concerns from other disciplines, such as Inflammation, Adverse effect, Phosphorylation and Cell-free system. His Opioid receptor research incorporates elements of -Naloxone and Ligand. His research investigates the connection between Endogenous opioid and topics such as Rheumatoid arthritis that intersect with issues in Cytotoxic T cell and Opioid peptide.

Between 2014 and 2021, his most popular works were:

  • A nontoxic pain killer designed by modeling of pathological receptor conformations (105 citations)
  • Analgesic efficacy of opioids in chronic pain: recent meta-analyses. (51 citations)
  • New concepts in opioid analgesia. (44 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Surgery

His primary scientific interests are in Opioid, Receptor, Pharmacology, Analgesic and Opioid receptor. Christoph Stein is involved in the study of Opioid that focuses on Opioid peptide in particular. His Receptor research is multidisciplinary, relying on both Inflammation, Phosphorylation and Cell-free system.

He has included themes like Endocrinology, Immune system and Proopiomelanocortin in his Inflammation study. His work is dedicated to discovering how Pharmacology, Agonist are connected with Heterotrimeric G protein and other disciplines. His research integrates issues of Chronic pain, Sedation, Cancer pain and Bioinformatics in his study of Analgesic.

Best Publications

  • Advances in Neuropathic Pain: Diagnosis, Mechanisms, and Treatment Recommendations

    Robert H. Dworkin;Miroslav Backonja;Michael C. Rowbotham;Robert R. Allen

  • The Control of Pain in Peripheral Tissue by Opioids

    Christoph Stein

  • Increased content and transport of substance P and calcitonin gene-related peptide in sensory nerves innervating inflamed tissue: evidence for a regulatory function of nerve growth factor in vivo.

    J. Donnerer;R. Schuligoi;C. Stein

  • Analgesic Effect of Intraarticular Morphine After Arthroscopic Knee Surgery

    C. Stein;K. Comisel;E. Haimerl;A. Yassouridis

  • Peripheral opioid receptors mediating antinociception in inflammation. Evidence for involvement of mu, delta and kappa receptors.

    C Stein;M J Millan;T S Shippenberg;K Peter

  • Attacking pain at its source: new perspectives on opioids.

    Christoph Stein;Michael Schäfer;Halina Machelska

  • Peripheral mechanisms of opioid analgesia.

    Christoph Stein

  • Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation.

    Christoph Stein;Ahmed H. S. Hassan;Ryszard Przewlocki;Christian Gramsch

  • Unilateral inflammation of the hindpaw in rats as a model of prolonged noxious stimulation: Alterations in behavior and nociceptive thresholds

    C. Stein;M.J. Millan;A. Herz

  • Inflammation of the rat paw enhances axonal transport of opioid receptors in the sciatic nerve and increases their density in the inflamed tissue

    A.H.S. Hassan;A. Ableitner;C. Stein;A. Herz

  • Interleukin 1 beta and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue

    Michael Schafer;Laurenda Carter;Christoph Stein

  • Perineurial defect and peripheral opioid analgesia in inflammation

    I Antonijevic;SA Mousa;M Schafer;C Stein

  • Immune cell-derived beta-endorphin. Production, release, and control of inflammatory pain in rats.

    P J Cabot;L Carter;C Gaiddon;Q Zhang

  • Gene expression and localization of opioid peptides in immune cells of inflamed tissue: functional role in antinociception.

    R. Przewlocki;A.H.S. Hassan;W. Lason;C. Epplen

  • Peripheral mechanisms of opioid analgesia

    Christoph Stein;Leonie Julia Lang

  • Local Analgesic Effect of Endogenous Opioid Peptides

    C. Stein;A. H. S. Hassan;K. Lehrberger;J. Giefing

  • Peripheral mechanisms of pain and analgesia

    Christoph Stein;J. David Clark;Uhtaek Oh;Michael R. Vasko

  • Intraarticular morphine, bupivacaine, and morphine/ bupivacaine for pain control after knee videoarthroscopy

    George F. Khoury;Andrew C. N. Chen;Douglas E. Garland;Christoph Stein

  • Intrinsic mechanisms of antinociception in inflammation: local opioid receptors and beta-endorphin.

    C Stein;C Gramsch;A Herz

  • Advances in neuropathic pain: Diagnosis, mechanisms, and treatment recommendations. Editorial

    Robert H. Dworkin;Miroslav Backonja;Michael C. Rowbotham;Robert R. Allen

Frequent Co-Authors

Albert Herz
Albert Herz Max Planck Society
Michael Schaefer
Michael Schaefer Leipzig University
Alexander Yassouridis
Alexander Yassouridis Max Planck Society
Rainer Haag
Rainer Haag Freie Universität Berlin
Burghardt Wittig
Burghardt Wittig Freie Universität Berlin
Michael M. Morgan
Michael M. Morgan Washington State University
Ryszard Przewlocki
Ryszard Przewlocki Polish Academy of Sciences
Toni S. Shippenberg
Toni S. Shippenberg National Institute on Drug Abuse
M. Catherine Bushnell
M. Catherine Bushnell National Institutes of Health
Linda R. Watkins
Linda R. Watkins University of Colorado Boulder

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