D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 56 Citations 8,973 206 World Ranking 8244 National Ranking 2454
Biology and Biochemistry D-index 56 Citations 8,741 200 World Ranking 10126 National Ranking 4431

Research.com Recognitions

Awards & Achievements

1984 - Fellow of Alfred P. Sloan Foundation

Overview

What is she best known for?

The fields of study Debra Dunaway-Mariano is best known for:

  • Enzyme
  • Amino acid
  • Gene

As part of her research on Biosynthesis, studies on Thioesterase and Adenylylation are part of the effort. By researching both Adenylylation and Biosynthesis, she produces research that crosses academic boundaries. Her research on Biochemistry often connects related topics like Dehalogenase. Her multidisciplinary approach integrates Enzyme and DNA ligase in her work. Debra Dunaway-Mariano conducted interdisciplinary study in her works that combined DNA ligase and Enzyme. Her Stereochemistry study frequently links to related topics such as Carboxylate. Her Carboxylate study frequently involves adjacent topics like Stereochemistry. Her Gene study frequently intersects with other fields, such as Dehalogenase. Debra Dunaway-Mariano undertakes interdisciplinary study in the fields of Active site and Hydrolase through her research.

Her most cited work include:

  • Evolutionary Genomics of the HAD Superfamily: Understanding the Structural Adaptations and Catalytic Diversity in a Superfamily of Phosphoesterases and Allied Enzymes (362 citations)
  • The Pentacovalent Phosphorus Intermediate of a Phosphoryl Transfer Reaction (294 citations)
  • Phosphoryl group transfer: evolution of a catalytic scaffold (245 citations)

What are the main themes of her work throughout her whole career to date

Her World Wide Web research includes a combination of various areas of study, such as Citation and Information retrieval. In her study, Debra Dunaway-Mariano carries out multidisciplinary Information retrieval and World Wide Web research. With her scientific publications, her incorporates both Biochemistry and Genetics. Genetics and Biochemistry are two areas of study in which Debra Dunaway-Mariano engages in interdisciplinary work. Her multidisciplinary approach integrates Enzyme and Enzyme kinetics in her work. Her study deals with a combination of Stereochemistry and Organic chemistry. She conducts interdisciplinary study in the fields of Organic chemistry and Stereochemistry through her works. Debra Dunaway-Mariano merges Active site with Catalysis in her research. She performs integrative study on Catalysis and Active site in her works.

Debra Dunaway-Mariano most often published in these fields:

  • Biochemistry (79.23%)
  • Enzyme (75.41%)
  • Stereochemistry (66.67%)

What were the highlights of her more recent work (between 2013-2018)?

  • Enzyme (90.00%)
  • Biochemistry (90.00%)
  • Stereochemistry (70.00%)

In recent works Debra Dunaway-Mariano was focusing on the following fields of study:

Her Ecology study frequently links to other fields, such as Substrate (aquarium) and Promiscuity. Substrate (aquarium) is frequently linked to Ecology in her study. Her work often combines Enzyme and Allosteric regulation studies. In her study, she carries out multidisciplinary Allosteric regulation and Phosphoglycerate mutase research. As part of her studies on Biochemistry, Debra Dunaway-Mariano frequently links adjacent subjects like Mutase. In her research, she performs multidisciplinary study on Mutase and Phosphoglycerate mutase. She connects Stereochemistry with Enzyme in her research. Her study deals with a combination of Active site and Enzyme catalysis. In her work, Debra Dunaway-Mariano performs multidisciplinary research in Phosphatase and Phosphate.

Between 2013 and 2018, her most popular works were:

  • Enzyme Promiscuity: Engine of Evolutionary Innovation (119 citations)
  • Structure of the Trehalose-6-phosphate Phosphatase from Brugia malayi Reveals Key Design Principles for Anthelmintic Drugs (30 citations)
  • Divergence of Substrate Specificity and Function in the Escherichia coli Hotdog-fold Thioesterase Paralogs YdiI and YbdB (15 citations)

In her most recent research, the most cited works focused on:

  • Enzyme
  • Lymphatic filariasis
  • Gene

Her study on Ecology is interrelated to topics such as Substrate (aquarium) and Promiscuity. Many of her studies on Substrate (aquarium) involve topics that are commonly interrelated, such as Ecology. Her Biochemistry study frequently links to adjacent areas such as Trehalose. Debra Dunaway-Mariano carries out multidisciplinary research, doing studies in Enzyme and Stereochemistry. In her research, Debra Dunaway-Mariano undertakes multidisciplinary study on Stereochemistry and Enzyme. Debra Dunaway-Mariano performs multidisciplinary studies into Gene and Computational biology in her work. Her study deals with a combination of Computational biology and Gene. Genetics connects with themes related to SUPERFAMILY in her study. Many of her studies involve connections with topics such as Escherichia coli and Enterobactin.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Evolutionary Genomics of the HAD Superfamily: Understanding the Structural Adaptations and Catalytic Diversity in a Superfamily of Phosphoesterases and Allied Enzymes

A. Maxwell Burroughs;Karen N. Allen;Debra Dunaway-Mariano;L. Aravind.
Journal of Molecular Biology (2006)

427 Citations

The Pentacovalent Phosphorus Intermediate of a Phosphoryl Transfer Reaction

Sushmita D. Lahiri;Guofeng Zhang;Debra Dunaway-Mariano;Karen N. Allen.
Science (2003)

378 Citations

Phosphoryl group transfer: evolution of a catalytic scaffold

Karen N. Allen;Debra Dunaway-Mariano.
Trends in Biochemical Sciences (2004)

319 Citations

Ancestry of the 4-chlorobenzoate dehalogenase: analysis of amino acid sequence identities among families of acyl:adenyl ligases, enoyl-CoA hydratases/isomerases, and acyl-CoA thioesterases.

Patricia C. Babbitt;George L. Kenyon;Brian M. Martin;Hugues Charest.
Biochemistry (1992)

267 Citations

Structure of 4-Chlorobenzoyl Coenzyme A Dehalogenase Determined to 1.8 Å Resolution: An Enzyme Catalyst Generated via Adaptive Mutation†,‡

Matthew M. Benning;Kimberly L. Taylor;Rui-Qin Liu;Guang Yang.
Biochemistry (1996)

224 Citations

Novel enzymic hydrolytic dehalogenation of a chlorinated aromatic.

Jeffrey D. Scholten;Kai-Hsuan Chang;Patricia C. Babbitt;Hugues Charest.
Science (1991)

191 Citations

The crystal structure of Bacillus cereus phosphonoacetaldehyde hydrolase: Insight into catalysis of phosphorus bond cleavage and catalytic diversification within the had enzyme superfamily

Marc C. Morais;Wenhai Zhang;Angela S. Baker;Guofeng Zhang.
Biochemistry (2000)

189 Citations

Acyl-adenylate motif of the acyl-adenylate/thioester-forming enzyme superfamily: a site-directed mutagenesis study with the Pseudomonas sp. strain CBS3 4-chlorobenzoate:coenzyme A ligase

Kai-Hsuan Chang;Hong Xiang;Debra Dunaway-Mariano.
Biochemistry (1997)

174 Citations

Investigations of substrate specificity and reaction mechanism of several kinases using chromium(III) adenosine 5'-triphosphate and chromium(III) adenosine 5'-diphosphate.

Debra Dunaway-Mariano;W. W. Cleland.
Biochemistry (1980)

165 Citations

Swiveling-domain mechanism for enzymatic phosphotransfer between remote reaction sites.

Osnat Herzberg;Celia C. H. Chen;Geeta Kapadia;Marielena McGuire.
Proceedings of the National Academy of Sciences of the United States of America (1996)

162 Citations

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