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D-Index & Metrics

Chemistry

D-Index
45
Citations
9250
World Ranking
16296
National Ranking
4062

Overview

Osnat Herzberg is affiliated with the University of Maryland, College Park in the United States. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with particular emphasis on Molecular Biology and Parasitology as key subfields. The scope of their work also touches upon Ecology, Materials Chemistry, and Genetics.

Herzberg's research contributions encompass a variety of topics, including:

  • Protein Structure and Dynamics
  • Bacteriophages and microbial interactions
  • RNA and protein synthesis mechanisms
  • Enzyme Structure and Function
  • Parasitic Infections and Diagnostics
  • Bacterial Genetics and Biotechnology
  • Vector-borne infectious diseases

The scientist has published work in several scientific venues, often contributing to:

  • Scientific Reports
  • mBio
  • Proteins Structure Function and Bioinformatics
  • Nucleic Acids Research
  • Proceedings of the National Academy of Sciences

Selected recent papers authored or co-authored by Herzberg include:

  • "Computational models in the service of X-ray and cryo-electron microscopy structure determination," 2021, Proteins Structure Function and Bioinformatics
  • "Structure and function of bacteriophage CBA120 ORF211 (TSP2), the determinant of phage specificity towards E. coli O157:H7," 2020, Scientific Reports
  • "Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia," 2022, Nucleic Acids Research
  • "Structure of Escherichia coli O157:H7 bacteriophage CBA120 tailspike protein 4 baseplate anchor and tailspike assembly domains (TSP4-N)," 2022, Scientific Reports
  • "More than just pattern recognition: Prediction of uncommon protein structure features by AI methods," 2023, Proceedings of the National Academy of Sciences

Frequent collaborators in their research include Sara B. Linden, Daniel Nelson, Julia Greenfield, Xiaoran Shang, and Kinlin Chao.

Best Publications

  • Structure of the calcium regulatory muscle protein troponin-C at 2.8 Å resolution

    Osnat Herzberg;Michael N. G. James

  • Crystal structure of the wide-spectrum binuclear zinc β-lactamase from Bacteroides fragilis

    N.O. Concha;B.A. Rasmussen;K. Bush;O. Herzberg

  • Crystal structure of the wide-spectrum binuclear zinc β-lactamase from Bacteroides fragilis

    Nestor O Concha;Beth A Rasmussen;Karen Bush;Osnat Herzberg

  • Bacterial resistance to beta-lactam antibiotics: crystal structure of beta-lactamase from Staphylococcus aureus PC1 at 2.5 A resolution.

    Osnat Herzberg;John Moult

  • Refined crystal structure of troponin C from turkey skeletal muscle at 2·0 Å resolution

    Osnat Herzberg;Michael N.G. James

  • Structure of S-lectin, a developmentally regulated vertebrate beta-galactoside-binding protein.

    Der-Ing Liao;Geeta Kapadia;Hafiz Ahmed;Gerardo R. Vasta

  • A model for the Ca2+-induced conformational transition of troponin C. A trigger for muscle contraction.

    O Herzberg;J Moult;M N James

  • Analysis of the steric strain in the polypeptide backbone of protein molecules.

    Osnat Herzberg;John Moult

  • Crosslinking of mammalian lectin (galectin-1) by complex biantennary saccharides.

    Yves Bourne;Barbara Bolgiano;Der-Ing Liao;Gérard Strecker

  • Refined crystal structure of beta-lactamase from Staphylococcus aureus PC1 at 2.0 A resolution.

    Osnat Herzberg

  • Structure of Human Hyaluronidase-1, a Hyaluronan Hydrolyzing Enzyme Involved in Tumor Growth and Angiogenesis

    Kinlin L. Chao;Lavanya Muthukumar;Osnat Herzberg

  • Swiveling-domain mechanism for enzymatic phosphotransfer between remote reaction sites.

    Osnat Herzberg;Celia C. H. Chen;Geeta Kapadia;Marielena McGuire

  • Biological function made crystal clear - annotation of hypothetical proteins via structural genomics.

    Edward Eisenstein;Gary L Gilliland;Osnat Herzberg;John Moult

  • Structure of the histidine-containing phosphocarrier protein HPr from Bacillus subtilis at 2.0-A resolution.

    Osnat Herzberg;Prasad Reddy;Sarah Sutrina;Milton H. Saier

  • Inhibition of beta-lactamase by clavulanate. Trapped intermediates in cryocrystallographic studies.

    Celia C.H. Chen;Osnat Herzberg

  • Common structural framework of the two Ca2+/Mg2+ binding loops of troponin C and other Ca2+ binding proteins.

    Osnat Herzberg;Michael N. G. James

  • Structural features of halophilicity derived from the crystal structure of dihydrofolate reductase from the Dead Sea halophilic archaeon, Haloferax volcanii.

    Ursula Pieper;Geeta Kapadia;Moshe Mevarech;Osnat Herzberg

  • Role of the omega-loop in the activity, substrate specificity, and structure of class A beta-lactamase.

    Soojay Banerjee;Ursula Pieper;Geeta Kapadia;Lewis K. Pannell

  • Structure of the IIA domain of the glucose permease of Bacillus subtilis at 2.2-A resolution.

    Der Ing Liao;Geeta Kapadia;Prasad Reddy;Milton H. Saier

  • Structure of a phosphonate-inhibited beta-lactamase. An analog of the tetrahedral transition state/intermediate of beta-lactam hydrolysis.

    Celia C.H. Chen;Jubrail Rahil;R.F. Pratt;Osnat Herzberg

  • Probing the calcium-induced conformational transition of troponin C with site-directed mutants.

    K. Fujimori;M. Sorenson;O. Herzberg;J. Moult

Frequent Co-Authors

Debra Dunaway-Mariano
Debra Dunaway-Mariano University of New Mexico
John Moult
John Moult University of Maryland, College Park
Michael N. G. James
Michael N. G. James University of Alberta
Gary L. Gilliland
Gary L. Gilliland National Institute of Standards and Technology
Andriy Kryshtafovych
Andriy Kryshtafovych University of California, Davis
Jonathan Reizer
Jonathan Reizer University of California, San Diego
Milton H. Saier
Milton H. Saier University of California, San Diego
Wei Zheng
Wei Zheng National Institutes of Health
Alan Peterkofsky
Alan Peterkofsky National Institutes of Health
Karen Bush
Karen Bush Indiana University

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