World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
79
Citations
19674
World Ranking
17702
National Ranking
8837

Overview

Toni S. Shippenberg was affiliated with the National Institute on Drug Abuse in the United States. Their research contributions primarily focused on the study of opioid receptors and related neurochemical pathways. Throughout their career, they contributed to an evolving understanding of receptor mechanisms and signaling, particularly in the context of pain mechanisms and treatments.

The scientist published multiple papers within prominent pharmacology and neuroscience venues, notably the IUPHAR/BPS Guide to Pharmacology CITE. Key publications include:

  • Opioid receptors in GtoPdb v.2023.1, 2023, IUPHAR/BPS Guide to Pharmacology CITE
  • Opioid receptors in GtoPdb v.2021.3, 2021, IUPHAR/BPS Guide to Pharmacology CITE
  • Opioid receptors in GtoPdb v.2025.1, 2025, IUPHAR/BPS Guide to Pharmacology CITE

Their frequent co-authors were:

  • Anna Borsodi
  • Michael R. Bruchas
  • Girolamo Calò
  • Charles Chavkin
  • MacDonald J. Christie

The main fields of study involved were Biochemistry, Genetics and Molecular Biology and Neuroscience. Subfields included Molecular Biology, Cellular and Molecular Neuroscience, and Physiology.

The broader topics of their research encompassed:

  • Neuropeptides and Animal Physiology
  • Pharmacological Receptor Mechanisms and Effects
  • Pain Mechanisms and Treatments
  • Receptor Mechanisms and Signaling

Best Publications

  • Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway

    Rainer Spanagel;Albert Herz;Toni S. Shippenberg

  • Peripheral opioid receptors mediating antinociception in inflammation. Evidence for involvement of mu, delta and kappa receptors.

    C Stein;M J Millan;T S Shippenberg;K Peter

  • The effects of opioid peptides on dopamine release in the nucleus accumbens : an in vivo microdialysis study

    Rainer Spanagel;Albert Herz;Toni S. Shippenberg

  • Neuroanatomical sites mediating the motivational effects of opioids as mapped by the conditioned place preference paradigm in rats.

    Regine Bals-Kubik;Annemarie Ableitner;Albert Herz;Toni S. Shippenberg

  • Dynorphin and the pathophysiology of drug addiction.

    T.S. Shippenberg;A. Zapata;V.I. Chefer

  • κ opioids selectively control dopaminergic neurons projecting to the prefrontal cortex

    Elyssa B. Margolis;Hagar Lock;Vladimir I. Chefer;Toni S. Shippenberg

  • Examination of the neurochemical substrates mediating the motivational effects of opioids: role of the mesolimbic dopamine system and D-1 vs. D-2 dopamine receptors.

    Toni S. Shippenberg;Regine Bals-Kubik;Albert Herz

  • Sensitization to the conditioned rewarding effects of cocaine: pharmacological and temporal characteristics.

    T S Shippenberg;C Heidbreder

  • Neural systems underlying opiate addiction.

    Taco J. De Vries;Toni S. Shippenberg

  • Overview of brain microdialysis.

    Vladimir I. Chefer;Alexis C. Thompson;Agustin Zapata;Toni S. Shippenberg

  • Mitogen-Activated Protein Kinase Regulates Dopamine Transporter Surface Expression and Dopamine Transport Capacity

    José A. Morón;Irina Zakharova;Jasmine V. Ferrer;Gerald A. Merrill

  • Shift from goal-directed to habitual cocaine seeking after prolonged experience in rats

    Agustin Zapata;Vicki L. Minney;Toni S. Shippenberg

  • Sensitization to the conditioned rewarding effects of morphine: pharmacology and temporal characteristics

    Toni S. Shippenberg;Ch. Heidbreder;Anthony Lefevour

  • Evidence that the aversive effects of opioid antagonists and kappa-agonists are centrally mediated.

    R Bals-Kubik;A Herz;T S Shippenberg

  • Place preference conditioning reveals the involvement of D1-dopamine receptors in the motivational properties of μ- and κ-opioid agonists

    T.S. Shippenberg;A. Herz

  • Deletion of the M5 muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia.

    Anthony S. Basile;Irina Fedorova;Agustin Zapata;Xiaoguang Liu

  • PI 3-kinase regulation of dopamine uptake.

    Lucia Carvelli;José A. Morón;Kristopher M. Kahlig;Jasmine V. Ferrer

  • D2 receptors regulate dopamine transporter function via an extracellular signal-regulated kinases 1 and 2-dependent and phosphoinositide 3 kinase-independent mechanism.

    Elizabeth A. Bolan;Bronwyn Kivell;Vanaja Jaligam;Murat Oz

  • Motivational properties of opioids: evidence that an activation of σ-receptors mediates reinforcement processes

    T.S. Shippenberg;R. Bals-Kubik;A. Herz

  • Motivational effects of opioids: influence of D-1 versus D-2 receptor antagonists.

    Toni S. Shippenberg;Albert Herz

Frequent Co-Authors

Albert Herz
Albert Herz Max Planck Society
Rainer Spanagel
Rainer Spanagel Heidelberg University
Georgy Bakalkin
Georgy Bakalkin Uppsala University
Osborne F. X. Almeida
Osborne F. X. Almeida Max Planck Institute of Psychiatry
Jonathan A. Javitch
Jonathan A. Javitch Columbia University
Susan Schenk
Susan Schenk Victoria University of Wellington
Lakshmi A. Devi
Lakshmi A. Devi Icahn School of Medicine at Mount Sinai
Miklós Tóth
Miklós Tóth Cornell University
Christoph Stein
Christoph Stein Charité - University Medicine Berlin
Amina S. Woods
Amina S. Woods National Institute on Drug Abuse

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring alternative online degrees can open up diverse career opportunities in the medical field. For registered nurses seeking advanced roles, asn to fnp programs allow you to bridge from an associate degree to becoming a family nurse practitioner, increasing your skill set and clinical responsibilities.

If you are interested in the growing field of wellness, accredited nutrition degrees online can lead to roles in health education, dietetics, and public health, offering the flexibility of remote study.

For those drawn to healthcare management and leadership, pursuing a master’s degree from cahme-accredited programs is an excellent way to ensure a high-quality, recognized education in healthcare administration.

Additionally, online rn-bsn programs without clinicals are designed for practicing nurses who wish to advance their qualifications without on-site clinical requirements, making higher education more accessible for busy professionals.

Best Scientists Citing Toni S. Shippenberg