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Biology and Biochemistry

D-Index
55
Citations
13615
World Ranking
14879
National Ranking
6228

Overview

Miklós Tóth is affiliated with Cornell University in the United States and conducts research primarily in the intersecting fields of medicine, biochemistry, genetics, molecular biology, and neuroscience. Their work focuses on neuroendocrine regulation and behavior, epigenetics and DNA methylation, stress responses including cortisol regulation, and disorders related to the pituitary gland.

The scientist's recent publications demonstrate a strong engagement with epigenetic mechanisms in brain function and development. For example, in 2020, Tóth authored Epigenetic Neuropharmacology: Drugs Affecting the Epigenome in the Brain, published in The Annual Review of Pharmacology and Toxicology. This work is part of a broader research interest encompassing topics such as single-cell and spatial transcriptomics, genetics related to neurodevelopmental disorders, and the biochemical pathways involving tryptophan linked to brain disorders.

Tóth's frequent coauthors reflect interdisciplinary collaborations, including Judit Gal Toth, Anika Nabila, Faten Taki, Katherine Lopez, and Paul Bergin, with multiple publications shared among these colleagues. Their research appears in various journals, with repeated contributions to iScience, bioRxiv (Cold Spring Harbor Laboratory), Cell Reports, and the Journal of the Endocrine Society, among others.

  • Epigenetic Neuropharmacology: Drugs Affecting the Epigenome in the Brain (2020, The Annual Review of Pharmacology and Toxicology)
  • Epigenomically Bistable Regions across Neuron-Specific Genes Govern Neuron Eligibility to a Coding Ensemble in the Hippocampus (2020, Cell Reports)
  • Maternal Programming of Social Dominance via Milk Cytokines (2020, iScience)
  • Regulation of embryonic and adult neurogenesis by Ars2 (2020, Development)
  • A transposase-derived gene required for human brain development (2023, bioRxiv (Cold Spring Harbor Laboratory))

The scientist's main areas of study are medicine (13 publications), biochemistry, genetics and molecular biology (12 publications), and neuroscience (8 publications). Within these, the most prominent subfields include molecular biology, social psychology, endocrinology, diabetes and metabolism, behavioral neuroscience, and pediatrics, perinatology, and child health.

  • Neuroendocrine regulation and behavior
  • Epigenetics and DNA Methylation
  • Stress Responses and Cortisol
  • Pituitary Gland Disorders and Treatments
  • Genetics and Neurodevelopmental Disorders
  • Single-cell and spatial transcriptomics
  • Tryptophan and brain disorders

Publication venues where Tóth frequently appears include:

  • iScience
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Journal of the Endocrine Society
  • The Annual Review of Pharmacology and Toxicology

Best Publications

  • Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior

    Zhe-Yu Chen;Deqiang Jing;Kevin G. Bath;Alessandro Ieraci

  • Increased anxiety of mice lacking the serotonin1A receptor

    Christopher L. Parks;Patricia S. Robinson;Etienne Sibille;Thomas Eugene Shenk

  • Cortical 5-HT2A Receptor Signaling Modulates Anxiety-Like Behaviors in Mice

    Noelia V. Weisstaub;Mingming Zhou;Alena Lira;Evelyn Lambe;Evelyn Lambe

  • Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin(1A) receptors.

    Zoltán Sarnyai;Etienne L. Sibille;Constantine Pavlides;Robert J. Fenster

  • Fragile X mice develop sensory hyperreactivity to auditory stimuli.

    L Chen;M Toth

  • Co-expression and In Vivo Interaction of Serotonin1A and Serotonin2A Receptors in Pyramidal Neurons of Prefrontal Cortex

    Mercè Amargós-Bosch;Analía Bortolozzi;M. Victoria Puig;Jordi Serrats

  • Involvement of 5-HT1A Receptors in Prefrontal Cortex in the Modulation of Dopaminergic Activity: Role in Atypical Antipsychotic Action

    Llorenç Díaz-Mataix;María Cecilia Scorza;Analía Bortolozzi;Miklos Toth

  • Increased stress response and β–phenylethylamine in MAOB –deficient mice

    Joseph Grimsby;Miklos Toth;Kevin Chen;Takeshi Kumazawa

  • Genetic inactivation of the Serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety.

    Etienne Sibille;Constantine Pavlides;Dietmar Benke;Miklos Toth

  • 5-HT1A receptor knockout mouse as a genetic model of anxiety

    Miklos Toth

  • The fragile x mental retardation protein binds and regulates a novel class of mRNAs containing u rich target sequences

    Chen L;Yun Sw;Seto J;Liu W

  • 5-Hydroxytryptamine Induces Mast Cell Adhesion and Migration

    Nataliya M. Kushnir-Sukhov;Alasdair M. Gilfillan;John W. Coleman;Jared M. Brown

  • Establishment of de novo DNA methylation patterns. Transcription factor binding and deoxycytidine methylation at CpG and non-CpG sequences in an integrated adenovirus promoter.

    Miklos Toth;Ulrich Müller;Walter Doerfler

  • Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects.

    A Bortolozzi;A Castañé;J Semakova;N Santana

  • Genomic sequencing reveals a 5-methylcytosine-free domain in active promoters and the spreading of preimposed methylation patterns

    Miklos Toth;Ursula Lichtenberg;Walter Doerfler

  • The 5-HT(1A) receptor knockout mouse and anxiety.

    Berend Olivier;T. Pattij;S. J. Wood;R. Oosting

  • In vivo actions of aripiprazole on serotonergic and dopaminergic systems in rodent brain

    Analía Bortolozzi;Llorenç Díaz-Mataix;Miklos Toth;Pau Celada

  • Cell-Mediated Immune Response to the Recombinant 57-kDa Heat-Shock Protein of Chlamydia trachomatis in Women with Salpingitis

    Steven S. Witkin;Jan Jeremias;Miklos Toth;William J. Ledger

  • Pheromone variation among eastern European and a western Asian population of the turnip moth Agrotis segetum.

    Bill S. Hansson;Miklós Tóth;Christer Löfstedt;Gábor Szöcs

  • Paradoxical anxiogenic response of juvenile mice to fluoxetine.

    Ji-eun Oh;Bojana Zupan;Steven Gross;Miklos Toth

Frequent Co-Authors

Wittko Francke
Wittko Francke Universität Hamburg
William J. Ledger
William J. Ledger University of New South Wales
Steven S. Witkin
Steven S. Witkin Cornell University
Michael A. Birkett
Michael A. Birkett Rothamsted Research
Christer Löfstedt
Christer Löfstedt Lund University
John A. Pickett
John A. Pickett Cardiff University
Bill S. Hansson
Bill S. Hansson Max Planck Society
Francesc Artigas
Francesc Artigas Spanish National Research Council
Etienne Sibille
Etienne Sibille University of Toronto
Thomas Shenk
Thomas Shenk Princeton University

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