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Overview

Leonard B. Seeff is affiliated with the Einstein Healthcare Network in the United States. Their research primarily focuses on medicine and the interdisciplinary fields of pharmacology, toxicology, and pharmaceutics. Within these domains, the scientist has contributed extensively to subfields such as pharmacology, pathology and forensic medicine, hepatology, epidemiology, and radiology, nuclear medicine and imaging.

Key topics in Leonard B. Seeff's work include:

  • Drug-Induced Hepatotoxicity and Protection
  • Tea Polyphenols and Effects
  • Hepatitis C virus research
  • Nephrotoxicity and Medicinal Plants
  • Tryptophan and brain disorders
  • Natural Compound Pharmacology Studies
  • Chemotherapy-induced organ toxicity mitigation

The scientist's publication record includes contributions to a range of journals and venues, with a noted frequency in the following:

  • UNC Libraries
  • Hepatology
  • Toxicology Reports
  • Clinical Gastroenterology and Hepatology
  • Clinical Liver Disease

Recent notable papers by Leonard B. Seeff cover topics related to hepatotoxicity and liver injury, reflecting a sustained interest in liver-related drug toxicity and rare adverse effects. These publications include:

  • United States Pharmacopeia (USP) comprehensive review of the hepatotoxicity of green tea extracts, 2020, Toxicology Reports
  • HLA-B*35:01 and Green Tea-Induced Liver Injury, 2020, Hepatology
  • Garcinia cambogia, Either Alone or in Combination With Green Tea, Causes Moderate to Severe Liver Injury, 2021, Clinical Gastroenterology and Hepatology
  • The 2020 Nobel Prize for Medicine or Physiology for the Discovery of Hepatitis C Virus: A Triumph of Curiosity and Persistence, 2021, Hepatology
  • The Origins of the Modern-Day Study of Drug Hepatotoxicity: Focus on Hyman J. Zimmerman, 2020, Clinical Liver Disease

Leonard B. Seeff has collaborated frequently with several other researchers in the field. Regular coauthors include:

  • Robert J. Fontana
  • Herbert L. Bonkovsky
  • Victor J. Navarro
  • Raj Vuppalanchi
  • Andrew Stolz

Best Publications

  • Diagnosis, management, and treatment of hepatitis C: An update

    Marc G. Ghany;Doris B. Strader;David L. Thomas;Leonard B. Seeff

  • Diagnosis, Management, and Treatment of Hepatitis C

    Doris B. Strader;Teresa Wright;Teresa Wright;David L. Thomas;Leonard B. Seeff;Leonard B. Seeff

  • An Update on Treatment of Genotype 1 Chronic Hepatitis C Virus Infection: 2011 Practice Guideline by the American Association for the Study of Liver Diseases

    Marc G. Ghany;David R. Nelson;Doris B. Strader;David L. Thomas

  • Pathogenesis, natural history, treatment, and prevention of hepatitis C.

    Liang Tj;Rehermann B;Seeff Lb;Hoofnagle Jh

  • Recovery, Persistence, and Sequelae in Hepatitis C Virus Infection: A Perspective on Long-Term Outcome

    Harvey J. Alter;Leonard B. Seeff

  • Seroconversion from hepatitis B e antigen to antibody in chronic type B hepatitis.

    J H Hoofnagle;G M Dusheiko;L B Seeff;E A Jones

  • Incidence of Hepatocellular Carcinoma and Associated Risk Factors in Hepatitis C-Related Advanced Liver Disease

    Anna S. Lok;Leonard B. Seeff;Timothy R. Morgan;Adrian M. di Bisceglie

  • Diagnosis and Monitoring of Hepatic Injury. I. Performance Characteristics of Laboratory Tests

    D. Robert Dufour;John A. Lott;Frederick S. Nolte;David R. Gretch

  • Peginterferon and Ribavirin for Chronic Hepatitis C

    Jay H. Hoofnagle;Leonard B. Seeff

  • Type B Hepatitis after Transfusion with Blood Containing Antibody to Hepatitis B Core Antigen

    Jay H. Hoofnagle;Leonard B. Seeff;Zelma Buskell Bales;Hyman J. Zimmerman

  • Diagnosis and Monitoring of Hepatic Injury. II. Recommendations for Use of Laboratory Tests in Screening, Diagnosis, and Monitoring

    D. Robert Dufour;John A. Lott;Frederick S. Nolte;David R. Gretch

  • Natural History of Hepatitis C

    David L. Thomas;Leonard B. Seeff

  • Type B hepatitis: the infectivity of blood positive for e antigen and DNA polymerase after accidental needlestick exposure

    Harvey J. Alter;Leonard B. Seeff;Paul M. Kaplan;Vincent J. McAuliffe

  • Hepatitis C and renal disease: an update

    Catherine M Meyers;Leonard B Seeff;Catherine O Stehman-Breen;Jay H Hoofnagle

  • 45-year follow-up of hepatitis C virus infection in healthy young adults.

    Leonard B. Seeff;Richard N. Miller;Charles S. Rabkin;Zelma Buskell-Bales

  • Complication Rate of Percutaneous Liver Biopsies Among Persons With Advanced Chronic Liver Disease in the HALT-C Trial

    Leonard B. Seeff;Gregory T. Everson;Timothy R. Morgan;Teresa M. Curto

  • Long-term mortality and morbidity of transfusion-associated non-A, non-B, and type C hepatitis: A National Heart, Lung, and Blood Institute collaborative study

    Leonard B. Seeff;Leonard B. Seeff;F. Blaine Hollinger;Harvey J. Alter;Elizabeth C. Wright

  • Causality assessment in drug‐induced liver injury using a structured expert opinion process: Comparison to the Roussel‐Uclaf causality assessment method

    Don C. Rockey;Leonard B. Seeff;James Rochon;James Freston

  • National Institutes of Health Consensus Development Conference panel statement: Management of hepatitis C

    D. W. Powell;B. Z. Abramson;J. A. Balint;S. Belle

  • Type B Hepatitis after Needle-Stick Exposure: Prevention with Hepatitis B Immune Globulin: Final Report of the Veterans Administration Cooperative Study

    L B Seeff;E C Wright;H J Zimmerman;H J Alter

Frequent Co-Authors

Jay H. Hoofnagle
Jay H. Hoofnagle National Institutes of Health
Anna Mae Diehl
Anna Mae Diehl Duke University
Robert H. Purcell
Robert H. Purcell National Institute of Allergy and Infectious Diseases
John L. Gerin
John L. Gerin Georgetown University Medical Center
Neil Kaplowitz
Neil Kaplowitz University of Southern California
Kamal G. Ishak
Kamal G. Ishak Armed Forces Institute of Pathology
Harvey J. Alter
Harvey J. Alter National Institutes of Health
Marc G. Ghany
Marc G. Ghany National Institutes of Health
Samuel W. French
Samuel W. French UCLA Medical Center
Anna S.F. Lok
Anna S.F. Lok University of Michigan–Ann Arbor

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