World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
10405
World Ranking
17095
National Ranking
1182

Overview

Burghardt Wittig is affiliated with Freie Universität Berlin in Germany, where their research focuses on areas within biochemistry, genetics, molecular biology, immunology, microbiology, and medicine. Their scholarly output covers a range of interconnected subjects within these fields.

Their recent publication includes the paper "Cell and gene therapy in Germany: three decades of advanced technologies", published in 2025 in the journal Immunotherapy. This work adds to the corpus of knowledge related to advanced therapeutic techniques in cell and gene therapy.

Wittig has collaborated with several frequent co-authors, including:

  • Manuel Schmidt
  • Matthias Schroff
  • Julie Allickson
  • Rafael G. Amado
  • Usman Azam

Their research has been published mainly in the venue:

  • Immunotherapy

Wittig's main fields of study are:

  • Biochemistry, Genetics and Molecular Biology
  • Immunology and Microbiology
  • Medicine

The subfields of study related to their work include:

  • Molecular Biology
  • Immunology
  • Oncology
  • Genetics

The primary research topics Wittig has explored involve:

  • Immunotherapy and Immune Responses
  • RNA Interference and Gene Delivery
  • Vaccines and Immunoinformatics Approaches
  • CAR-T Cell Therapy Research
  • Virus-based Gene Therapy Research
  • Viral Infectious Diseases and Gene Expression in Insects

Best Publications

  • Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents

    C. Kleuss;J. Hescheler;C. Ewel;W. Rosenthal

  • Different β-subunits determine G-protein interaction with transmembrane receptors

    C. Kleuss;H. Scherübl;J. Hescheler;G. Schultz

  • Selectivity in signal transduction determined by gamma subunits of heterotrimeric G proteins

    Christiane Kleuss;Hans Scherübl;Jürgen Hescheler;Günter Schultz

  • Angiotensin II Activates Nuclear Transcription Factor κB Through AT1 and AT2 in Vascular Smooth Muscle Cells Molecular Mechanisms

    Marta Ruiz-Ortega;Oscar Lorenzo;Mónica Rupérez;Sven König

  • One- and Two-Photon Excited Optical pH Probing for Cells Using Surface-Enhanced Raman and Hyper-Raman Nanosensors

    Janina Kneipp;Harald Kneipp;Burghardt Wittig;Katrin Kneipp

  • Novel optical nanosensors for probing and imaging live cells.

    Janina Kneipp;Janina Kneipp;Harald Kneipp;Harald Kneipp;Burghardt Wittig;Katrin Kneipp;Katrin Kneipp

  • Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene.

    G Buschhausen;B Wittig;M Graessmann;A Graessmann

  • Therapeutic vaccination against metastatic carcinoma by expression-modulated and immunomodified autologous tumor cells: a first clinical phase I/II trial.

    Burghardt Wittig;Angela Märten;Tomislav Dorbic;Silvia Weineck

  • Phase I clinical study applying autologous immunological effector cells transfected with the interleukin-2 gene in patients with metastatic renal cancer, colorectal cancer and lymphoma.

    I. G. H. Schmidt-Wolf;S. Finke;B. Trojaneck;A. Denkena

  • Lack of Interferon Consensus Sequence Binding Protein (ICSBP) Transcripts in Human Myeloid Leukemias

    Manuel Schmidt;Stefan Nagel;Jutta Proba;Christian Thiede

  • Vaccination with IL-12 gene-modified autologous melanoma cells: preclinical results and a first clinical phase I study.

    Y Sun;K Jurgovsky;K Jurgovsky;P Möller;S Alijagic

  • Following the Dynamics of pH in Endosomes of Live Cells with SERS Nanosensors

    Janina Kneipp;Harald Kneipp;Burghardt Wittig;Katrin Kneipp

  • Transcription of human c-myc in permeabilized nuclei is associated with formation of Z-DNA in three discrete regions of the gene.

    B. Wittig;S. Wölfl;T. Dorbic;W. Vahrson

  • SIMPLE AND SENSITIVE DETECTION OF MUTATIONS IN THE RAS PROTO-ONCOGENES USING PNA-MEDIATED PCR CLAMPING

    Christian Thiede;Ekkehard Bayerdörffer;Rainer Blasczyk;Burghardt Wittig

  • Transcription is associated with Z-DNA formation in metabolically active permeabilized mammalian cell nuclei.

    Burghardt Wittig;Tomislav Dorbic;Alexander Rich

  • SuperPred: drug classification and target prediction.

    Mathias Dunkel;Stefan Günther;Jessica Ahmed;Burghardt Wittig

  • Interferon-α, but not the ABL-kinase inhibitor imatinib (STI571), induces expression of myeloblastin and a specific T-cell response in chronic myeloid leukemia

    Andreas Burchert;Stefan Wölfl;Manuel Schmidt;Cornelia Brendel

  • Short-Course Toll-Like Receptor 9 Agonist Treatment Impacts Innate Immunity and Plasma Viremia in Individuals With Human Immunodeficiency Virus Infection

    Line Vibholm;Line Vibholm;Mariane H. Schleimann;Mariane H. Schleimann;Jesper F. Højen;Jesper F. Højen;Thomas Benfield

  • TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23.

    Ehsan Aliahmadi;Robert Gramlich;Andreas Grützkau;Manuel Hitzler

  • Vaccination with IL-7 gene-modified autologous melanoma cells can enhance the anti-melanoma lytic activity in peripheral blood of patients with a good clinical performance status: a clinical phase I study

    P Möller;Y Sun;T Dorbic;S Alijagic

Frequent Co-Authors

Ingo G.H. Schmidt-Wolf
Ingo G.H. Schmidt-Wolf University Hospital Bonn
Werner Scheithauer
Werner Scheithauer Medical University of Vienna
Hans-Joachim Schmoll
Hans-Joachim Schmoll Martin Luther University Halle-Wittenberg
Günter Schultz
Günter Schultz Freie Universität Berlin
Lars Østergaard
Lars Østergaard Aarhus University Hospital
Günter Henze
Günter Henze Charité - University Medicine Berlin
Christoph Stein
Christoph Stein Charité - University Medicine Berlin
Janina Kneipp
Janina Kneipp Humboldt-Universität zu Berlin
Michael Schaefer
Michael Schaefer Leipzig University

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